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Karl Egan
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Journal Articles

Comprehensive Multi-Parameter Characterisation of Circulating Extracellular Vesicles from Rivaroxaban-Treated VTE Patients Reveals Reduced Inflammation and Ameliorated Endothelial Dysfunction

Free
Luisa Weiss, Paulina Szklanna, Tadhg Prendiville, Karl Egan, Sarah Kelliher, Aine Lennon, Eugene Dillon, Alfonso Blanco, Barry Kevane, Sean Murphy, Fionnuala Ni Ainle, Patricia Maguire
Journal: Blood
Blood (2021) 138 (Supplement 1): 3210.
https://doi.org/10.1182/blood-2021-146131
Published: 2021
Journal Articles

Rivaroxaban Reduces the Levels of Extracellular Vesicles in Patients with Venous Thromboembolism and Non-Valvular Atrial Fibrillation

Free
Sarah Kelliher, MBBS, Luisa Weiss, MSc, Paulina Szklanna, PhD, Karl Egan, PhD, Tadhg Prendiville, MB BCh BAO, Eric Moran, MB BCh BAO, Georgi Petrov, MB BCh BAO, Alfonso Blanco, PhD, Aine Lennon, MSc, Sean Murphy, MD, John Keaney, MD, Fionnuala Ni Ainle, PhD, Patricia Maguire, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2437.
https://doi.org/10.1182/blood-2019-126166
Published: 2019
Journal Articles

The Hundred-Person Platelet Releasate Project (100PREPs): A Barcode for Human Health and Disease

Free
Patricia Maguire, PhD, Paulina Szklanna, PhD, Martin Parsons, PhD, Kieran Wynne, MSc, Hugh O'Connor, MD, Karen O'Connell, MD, Karl Egan, PhD, Christopher McGuigan, MD PhD, Scott Rickard, PhD, Fionnuala Ni Ainle, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3735.
https://doi.org/10.1182/blood-2018-99-115421
Published: 2018
Journal Articles

Characterization of Platelet Activation in Patients with Eisenmenger Syndrome

Free
Gordon Haire, MB, Karl Egan, PhD, Barry Kevane, MB, Michael Fay, MB, FRCPath, Anne Fortune, MB, FRCPath, Rhona Savage, BSc, Esther Doran, BSc, Ciara O'Neill, BSc, Kevin Walsh, MD, Damien Kenny, MD, Aine Lennon, MSc, Patricia Maguire, PhD, Fionnuala Ni Ainle, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4973.
https://doi.org/10.1182/blood-2018-99-116914
Published: 2018
Journal Articles

The Population of Circulating Extracellular Vesicles Dramatically Alters after Very Premature Delivery- a Previously Unrecognised Postnatal Adaptation Process?

Free
Daniel O'Reilly, MBBS, BSc, Karl Egan, PhD, Oscar Burke, BSc, Angharad Griffiths, Elaine Neary, MD, Alfonso Blanco, PhD, Paulina Szklanna, PhD, Patricia Maguire, PhD, Naomi McCallion, Fionnuala Ni Ainle, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1129.
https://doi.org/10.1182/blood-2018-99-113180
Published: 2018
Journal Articles

Tissue Factor Pathway Inhibitor Mediates Attenuation of Tissue Factor-Stimulated Thrombin Generation in Early Onset Preeclampsia

Free
Karl Egan, Hugh O'Connor, Barry Kevane, MB, Fergal Malone, Amani Al Zadjali, Sharon Cooley, Cathy Monteith, Patricia Maguire, PhD, Paulina Szklanna, BSc, Seamus Allen, PhD, Naomi McCallion, Fionnuala Ní Áinle, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1431.
https://doi.org/10.1182/blood.V128.22.1431.1431
Published: 2016
Journal Articles

A Novel Beneficial Role for Macitentan in Patients at High Thrombosis Risk: Attenuation of Platelet-Mediated Derangements of Blood Coagulation in Eisenmenger Syndrome

Free
Barry Kevane, MB, Seamus Allen, PhD, Kevin Walsh, MD, Karl Egan, PhD, Patricia Maguire, PhD, Damien Kenny, MD, Susan Crawford, BSc, Áine Lennon, BSc, Rhona Savage, BSc, Esther Doran, BSc, Elaine Neary, MD, Fionnuala Ní Áinle, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2602.
https://doi.org/10.1182/blood.V128.22.2602.2602
Published: 2016
Journal Articles

Endothelial Protective Properties of Low Molecular Weight Heparin (LMWH) Tinzaparin in Combination with Statin: A Novel Potential Therapeutic Tool in Preventing Cancer Metastasis?

Free
Barry Kevane, MB, Karl Egan, PhD, Seamus Allen, PhD, Patricia Maguire, PhD, Elaine Neary, MD, Áine Lennon, BSc, Fionnuala Ní Áinle, MD PhD
Journal: Blood
Blood (2016) 128 (22): 881.
https://doi.org/10.1182/blood.V128.22.881.881
Published: 2016
Journal Articles

Increased Soluble GPVI Levels in Cirrhosis: Evidence for Collagen Induced Platelet Activation In Vivo

Free
Karl Egan, PhD, Eimear Dunne, Audrey Dillon, Barry Kevane, MB, Zita Galvin, Dermot Kenny, MD, Stephen Stewart, Fionnuala Ní Áinle, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1114.
https://doi.org/10.1182/blood.V126.23.1114.1114
Published: 2015
Journal Articles

Platelet-Derived Beta Thromboglobulin: A Potential Novel Activator of Coagulation Factor X

Free
Karl Egan, PhD, Hui Ma, PhD, Barry Kevane, MB, Áine Lennon, BSc, Elaine Neary, MD, Kieran Wynne, Seamus Allen, PhD, Susan O'Shea, MB, BCH, MHS, Richard O Kennedy, Fionnuala Ní Áinle, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2276.
https://doi.org/10.1182/blood.V126.23.2276.2276
Published: 2015
Journal Articles

To Characterize Standard Laboratory Coagulation Parameters and Plasma Thrombin Generation in Very Preterm Infants and to Investigate Their Relationship to Clinical Outcomes

Free
Elaine Neary, MB, BCh, BAO, MRCPI, MSC, PGDIP, Naomi McCallion, MB, BCh, BAO, MRCPI, MD, Barry Kevane, MB, BCh, BAO, Melanie Cotter, MB, BCh, BAO, DCH, MSc, FRCPI, FRCPath, MD, Karl Egan, BSc, PhD, Regan Irene, FRCPath, FAMLS, MSc, MBA, HDip Train Educ, Fionnuala Ní Áinle, PhD MB, MRCPI, FRCPath
Journal: Blood
Blood (2014) 124 (21): 2827.
https://doi.org/10.1182/blood.V124.21.2827.2827
Published: 2014