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Karim Kentouche
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Journal Articles

Recombinant ADAMTS13 Prophylaxis in Pediatric Patients with Congenital Thrombotic Thrombocytopenic Purpura: Results from the Phase 3 Randomized, Crossover Study and the Phase 3b Continuation Study

Marie Scully, Claire Berger, Nathalie Biebuyck, Santiago Bonanad Boix, Claire Dossier, Wolf-Achim Hassenpflug, Karim Kentouche, Beverly Schaefer, Silvia Maria Trisolini, Runhui Wu, Juan Xiao, Feng Xue, Björn Mellgård, Munjal Patel, Parth Patwari, Linda T. Wang, Shan Xiao, Pinghai Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 141.
https://doi.org/10.1182/blood-2024-199087
Published: 2024
Journal Articles

Recombinant ADAMTS-13: first-in-human pharmacokinetics and safety in congenital thrombotic thrombocytopenic purpura

Clinical Trials & Observations
Marie Scully, Paul Knöbl, Karim Kentouche, Lawrence Rice, Jerzy Windyga, Reinhard Schneppenheim, Johanna A. Kremer Hovinga, Michiko Kajiwara, Yoshihiro Fujimura, Caterina Maggiore, Jennifer Doralt, Christopher Hibbard, Leah Martell, Bruce Ewenstein
Journal: Blood
Blood (2017) 130 (19): 2055–2063.
https://doi.org/10.1182/blood-2017-06-788026
Published: 2017
Includes: Supplemental data
Journal Articles

Pharmacodynamic Profile of a Recombinant ADAMTS13 (BAX930) in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome (USS))

Marie Scully, Paul Knoebl, MD, Karim Kentouche, Lawrence Rice, MD, Jerzy Windyga, MD, Reinhard Schneppenheim, Johanna A Kremer Hovinga, MD PhD, Michiko Kajiwara, Caterina Maggiore, Jennifer Doralt, Leah Martell, Bruce M. Ewenstein
Journal: Blood
Blood (2016) 128 (22): 135.
https://doi.org/10.1182/blood.V128.22.135.135
Published: 2016
Journal Articles

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice

Simon Stritt, Markus Bender, Paquita Nurden, MD PhD, Judith van Eeuwijk, Barbara Zieger, Prof, Karim Kentouche, MD, Harald Schulze, Prof, Henner Morbach, MD, David Stegner, PhD, Katrin G Heinze, PhD, Sebastian Dütting, PhD, Shuchi Gupta, PhD, Walter Witke, Prof, Hervé Falet, PhD, Alain Fischer, Prof, John H. Hartwig, Prof, Bernhard Nieswandt, Prof
Journal: Blood
Blood (2014) 124 (21): 4200.
https://doi.org/10.1182/blood.V124.21.4200.4200
Published: 2014
Journal Articles

The splenic autoimmune response to ADAMTS13 in thrombotic thrombocytopenic purpura contains recurrent antigen-binding CDR3 motifs

Monica Schaller, Monique Vogel, Karim Kentouche, Bernhard Lämmle, Johanna A. Kremer Hovinga
Journal: Blood
Blood (2014) 124 (23): 3469–3479.
https://doi.org/10.1182/blood-2014-04-561142
Published: 2014
Includes: Supplemental data
Journal Articles

Abnormally differentiated CD4 + or CD8 + T cells with phenotypic and genetic features of double negative T cells in human Fas deficiency

Anne Rensing-Ehl, Simon Völkl, Carsten Speckmann, Myriam Ricarda Lorenz, Julia Ritter, Ales Janda, Mario Abinun, Hanspeter Pircher, Bertram Bengsch, Robert Thimme, Ilka Fuchs, Sandra Ammann, Andrea Allgäuer, Karim Kentouche, Andrew Cant, Sophie Hambleton, Claudia Bettoni da Cunha, Sebastian Huetker, Ingrid Kühnle, Arnulf Pekrun, Markus G. Seidel, Michael Hummel, Andreas Mackensen, Klaus Schwarz, Stephan Ehl
Journal: Blood
Blood (2014) 124 (6): 851–860.
https://doi.org/10.1182/blood-2014-03-564286
Published: 2014
Includes: Supplemental data
Journal Articles

High-Throughput Screening of a Large Combinatorial Library of Small Proteins Against Human Spleen-Derived Monoclonal Anti-ADAMTS13 Antibodies Yields Specific Anti-Idiotypic Molecules – Potential Tools for New Treatment Strategy in Acquired TTP

Monica Schaller, PhD, Sabine Hiltbrunner, Irmela Sulzer, Monique Vogel, PhD, Karim Kentouche, MD, Bernhard Laemmle, MD, Johanna A. Kremer Hovinga
Journal: Blood
Blood (2012) 120 (21): 487.
https://doi.org/10.1182/blood.V120.21.487.487
Published: 2012
Journal Articles

Inhibitory Spleen-Derived Anti-ADAMTS13 Antibodies Are Characterized by a Limited Number of Variable Heavy Chain CDR3 Signatures in Patients with Relapsing Acquired Thrombotic Thromobocytopenic Purpura

Monica Schaller, PhD, Gianna Tanno, Irmela Sulzer, Monique Vogel, PhD, Karim Kentouche, MD, Bernhard Laemmle, MD, Johanna A. Kremer Hovinga Strebel, MD
Journal: Blood
Blood (2011) 118 (21): 194.
https://doi.org/10.1182/blood.V118.21.194.194
Published: 2011
Journal Articles

Restricted Immunglobulin Gene Usage of Spleen-Derived Specific Anti-ADAMTS13 B-Cells In Relapsing TTP Treated with or without Rituximab.

Monica M. Schaller Tschan, PhD, Karin Sprecher, Master, Irmela Sulzer, technician, Monique Vogel, PhD, Beda Stadler, Prof, Karim Kentouche, MD, Bernhard Lämmle, Prof, Johanna A. Kremer Hovinga Strebel, MD
Journal: Blood
Blood (2010) 116 (21): 1431.
https://doi.org/10.1182/blood.V116.21.1431.1431
Published: 2010
Journal Articles

Laboratory Response to Desmopressin in Children with Von Willebrand Disease: Results of a Multicenter Survey

Bianca Huhn, Volker Aumann, Andre Hofmann, Karim Kentouche, Axel Sauerbrey, Harry Sirb, Thomas Winkelmann, Ralf Knoefler
Journal: Blood
Blood (2008) 112 (11): 4517.
https://doi.org/10.1182/blood.V112.11.4517.4517
Published: 2008
Journal Articles

von Willebrand factor cleaving protease and ADAMTS13 mutations in childhood TTP

Clinical Trials & Observations
Reinhard Schneppenheim, Ulrich Budde, Florian Oyen, Dorothea Angerhaus, Volker Aumann, Elke Drewke, Wolf Hassenpflug, Johannes Häberle, Karim Kentouche, Elisabeth Kohne, Karin Kurnik, Dirk Mueller-Wiefel, Tobias Obser, René Santer, Karl-Walter Sykora
Journal: Blood
Blood (2003) 101 (5): 1845–1850.
https://doi.org/10.1182/blood-2002-08-2399
Published: 2003