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K. Gary Vanasse
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Journal Articles

Phase 1 Study Update of the Novel Pan-Pim Kinase Inhibitor LGH447 in Patients with Relapsed/ Refractory Multiple Myeloma

Marc S Raab, MD PhD, Enrique M Ocio, Sheeba K. Thomas, MD, Andreas Günther, MD, Yeow-Tee Goh, MBBS,MMed, Daniel Lebovic, MD, Andrzej Jakubowiak, MD PhD, Dongweon Song, F Xiang, Apurva Patel, K. Gary Vanasse, MD, Shaji Kumar, MD
Journal: Blood
Blood (2014) 124 (21): 301.
https://doi.org/10.1182/blood.V124.21.301.301
Published: 2014
Journal Articles

ABL001, a Potent Allosteric Inhibitor of BCR-ABL, Prevents Emergence of Resistant Disease When Administered in Combination with Nilotinib in an in Vivo Murine Model of Chronic Myeloid Leukemia

Andrew Wylie, PhD, Joseph Schoepfer, Giuliano Berellini, Hongbo Cai, Giorgio Caravatti, Simona Cotesta, Stephanie Dodd, Jerry Donovan, Bernhard Erb, Pascal Furet, Geeti Gangal, Robert Grotzfeld, Quamrul Hassan, Tami Hood, Varsha Iyer, Sandra Jacob, Wolfgang Jahnke, Franco Lombardo, Alice Loo, Paul W. Manley, Ph. D., Andreas Marzinzik, Michael Palmer, Xavier Pelle, Bahaa Salem, Sreenath Sharma, Sanjeev Thohan, Suzanne Zhu, Nicholas Keen, Lilli Petruzzelli, MDPhD, K. Gary Vanasse, MD, William R Sellers, MD
Journal: Blood
Blood (2014) 124 (21): 398.
https://doi.org/10.1182/blood.V124.21.398.398
Published: 2014
Journal Articles

Phase 1 Study Of The Novel Pan-Pim Kinase Inhibitor LGH447 In Patients With Relapsed/ Refractory Multiple Myeloma

Marc S Raab, MD, Enrique M. Ocio, Sheeba K. Thomas, M.D., Andreas Günther, Daniel Lebovic, MD, Shaji K Kumar, MD, Andrzej J. Jakubowiak, MD, PhD, Dongweon Song, Fang Xiang, David Hynds, K. Gary Vanasse, M.D., Yeow Tee Goh, MD
Journal: Blood
Blood (2013) 122 (21): 3186.
https://doi.org/10.1182/blood.V122.21.3186.3186
Published: 2013
Journal Articles

The Combination Of JAK Inhibitor, Ruxolitinib, and PIM Inhibitor, LGH447, In Preclinical Models Of Myeloproliferative Neoplasia

Abdel Saci, Ph.D., Maria Pinzon-Ortiz, Dannie Wang, Xianhui Rong, Joseph Growney, Ph.D., Margaret Squier, MD, PhD, Thomas Radimerski, PhD, K. Gary Vanasse, Giordano Caponigro, Pablo D Garcia, PhD, Z. Alexander Cao
Journal: Blood
Blood (2013) 122 (21): 4100.
https://doi.org/10.1182/blood.V122.21.4100.4100
Published: 2013
Journal Articles

The Pan-PIM Kinase Inhibitor LGH447 Shows Activity In PIM2-Dependent Multiple Myeloma and In AML Models

Pablo D Garcia, PhD, John L Langowski, Ph.D., Jocelyn Holash, Ph.D., Matthew Burger, Ph.D., Richard Zang, Ph.D., Tatiana Zavorotinskaya, PhD, Christie Fanton, PhD, Abdel Saci, Ph.D., Joseph Growney, Ph.D., K. Gary Vanasse, M.D.
Journal: Blood
Blood (2013) 122 (21): 1666.
https://doi.org/10.1182/blood.V122.21.1666.1666
Published: 2013