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Julia E. Maxson, PhD
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Journal Articles

FLT3 and LSD1 Inhibitor Combinations Synergistically Repress Growth of FLT3-Mutant Acute Myeloid Leukemia Via Blockage of MYC Function

Daniel J. Coleman, PhD, Brittany M. Smith, Cody Coblentz, Rowan L. Callahan, Jake VanCampen, Garth L. Kong, Brian J. Druker, MD, Julia E. Maxson, PhD, Theodore P. Braun, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-143029
Published: 2020
Journal Articles

Oncogenic SETBP1 Mutations Combine with Activating Mutations in CSF3R to Produce a Highly Proliferative, Lethal Leukemia through Aberrant Myc Signaling

Sarah A Carratt, PhD BS, Theodore P. Braun, MDPhD, Zachary Schonrock, BS, Brittany M. Smith, Daniel J Coleman, PhD, Garth Kong, MS, Joseph Estabrook, MS, Adrian Baris, Lauren Maloney, Julia E. Maxson, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 51–52.
https://doi.org/10.1182/blood-2020-143072
Published: 2020
Journal Articles

Myeloid-Lineage Enhancers Drive Oncogene Synergy and Represent a Novel Therapeutic Target in CSF3R-CEBPA Mutant AML

Theodore Braun, MD PhD, Cody Coblentz, Sarah A Carratt, PhD BS, Mariam Okhovat, PhD, Amy Foley, MEng., Zachary Schonrock, BS, Kimberly Nevonen, Rhonda E. Ries, MA, Shannon K. McWeeney, PhD, Claus Nerlov, PhD, Soheil Meshinchi, MD PhD, Lucia Carbone, PhD, Brian J. Druker, Julia E. Maxson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 543.
https://doi.org/10.1182/blood-2019-124773
Published: 2019
Journal Articles

Single Cell RNA Sequencing Identifies a Crucial Role for ASXL1 in Neutrophil Development

Theodore Braun, MD PhD, Theresa Lusardi, PhD, Trevor Enright, MS, Zachary Schonrock, BS, Cody Coblentz, Hisham Mohamed, PhD, Brian J. Druker, Julia E. Maxson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 212.
https://doi.org/10.1182/blood-2019-125022
Published: 2019
Journal Articles

SETBP1 Mutations Accelerate NRAS-Mutant Leukemia

Sarah A Carratt, PhD BS, Zachary Schonrock, BS, Theodore Braun, MD PhD, Cody Coblentz, Amy Foley, MEng., Julia E. Maxson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1254.
https://doi.org/10.1182/blood-2019-125125
Published: 2019
Journal Articles

CSF3R Mutations Synergize with CEBPA and SETBP1 Mutations in Acute Myeloid Leukemia and Chronic Neutrophilic Leukemia

Amy Foley, MEng., Seamus B Hughes, Soheil Meshinchi, MD PhD, Julia E. Maxson, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3963.
https://doi.org/10.1182/blood.V130.Suppl_1.3963.3963
Published: 2017
Journal Articles

Therapeutically Targetable Activating c-ABL1 Mutations in Philadelphia Chromosome-Negative Leukemias

Samantha L Savage, Julia E. Maxson, PhD, Christopher A. Eide, Chelsea Jenkins, B.S., Melissa L Abel, Anna M. Reister Schultz, Daniel Bottomly, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Cristina E. Tognon, PhD, Jeffrey W. Tyner, PhD, Brian J. Druker, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3930.
https://doi.org/10.1182/blood.V130.Suppl_1.3930.3930
Published: 2017
Journal Articles

Distinct Mechanisms of Receptor Activation Are Associated with CSF3R Gain-of-Function Mutations

Haijiao Zhang, Julia E. Maxson, PhD, Kevin M Watanabe-Smith, PhD, Cody Coblentz, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4985.
https://doi.org/10.1182/blood.V130.Suppl_1.4985.4985
Published: 2017
Journal Articles

Recurrent Pathogenic Cyclin D2 Mutations in Myeloid Malignancies

Vishesh Khanna, BS, Christopher A. Eide, Cristina E. Tognon, Julia E. Maxson, PhD, Beth Wilmot, Daniel Bottomly, Shannon K. McWeeney, Brian J. Druker, MD, Jeffrey W. Tyner
Journal: Blood
Blood (2016) 128 (22): 2734.
https://doi.org/10.1182/blood.V128.22.2734.2734
Published: 2016
Journal Articles

A Novel CSF3R Mutation Uncovers the Importance of Membrane-Proximal N-Glycosylation for Receptor Regulation

Seamus B Hughes, David Spiciarich, Richard D. Press, Sarah L Thompson, Jerald P. Radich, Carolyn Bertozzi, Stephen T. Oh, MD PhD, Julia E. Maxson, PhD
Journal: Blood
Blood (2016) 128 (22): 3141.
https://doi.org/10.1182/blood.V128.22.3141.3141
Published: 2016
Journal Articles

PTPN11 Mutations in JMML Confer Dasatinib Sensitivity in a TNK2-Dependent Manner

Chelsea Jenkins, B.S., Samuel B Luty, BS, Julia E. Maxson, PhD, Christopher A. Eide, Bill H. Chang, MD PhD, Jeffrey W. Tyner
Journal: Blood
Blood (2016) 128 (22): 3154.
https://doi.org/10.1182/blood.V128.22.3154.3154
Published: 2016
Journal Articles

The CSF3R T618I Mutation Found In Chronic Neutrophilic Leukemia Removes An O-Linked Glycosylation Site and Increases Receptor Dimerization

Julia E. Maxson, PhD, Jason Gotlib, MD, MS, Daniel A. Pollyea, MD, MS, Angela G. Fleischman, MD, PhD, Anupriya Agarwal, Samuel B. Luty, BS, Melissa Abel, Christopher A. Eide, Daniel Bottomly, Beth Wilmot, Shannon K. McWeeney, Cristina E. Tognon, Robert H. Collins, Jr., MD, J. Blake Pond, M.S, Basem Goueli, M.D., Stephen T. Oh, MD, PhD, Michael W. Deininger, MD, PhD, Bill H. Chang, MD, PhD, Marc M. Loriaux, Brian J. Druker, Jeffrey W. Tyner
Journal: Blood
Blood (2013) 122 (21): 270.
https://doi.org/10.1182/blood.V122.21.270.270
Published: 2013
Journal Articles

CSF3R T618I Mouse Bone Marrow Transplant Model Of Neutrophilic Leukemia

Julia E Maxson, PhD, Angela G. Fleischman, MD, PhD, Samuel B Luty, BS, Lacey R Royer, Anupriya Agarwal, Marc M. Loriaux, Brian J. Druker, Jeffrey W. Tyner
Journal: Blood
Blood (2013) 122 (21): 223.
https://doi.org/10.1182/blood.V122.21.223.223
Published: 2013
Journal Articles

A Truncation Mutant of CSF3R, Identified As a Novel Driver in De Novo Myeloid Leukemia, Signals Through TNK2, and Is Responsive to Dasatinib.

Julia E Maxson, PhD, Jason Gotlib, Angela G. Fleischman, MD, PhD, Christopher A. Eide, Daniel Bottomly, MS, Beth Wilmot, PhD, MS, Shannon McWeeney, PhD, Cristina Tognon, PhD, Marc M Loriaux, MD, PhD, Brian J. Druker, Jeffrey W Tyner, PhD
Journal: Blood
Blood (2012) 120 (21): 2412.
https://doi.org/10.1182/blood.V120.21.2412.2412
Published: 2012