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Journal Articles

Carfilzomib, Elotuzumab and Dexamethasone for Relapsed or Refractory Myeloma Patients

Raija Helena Silvennoinen, MDPhD, Hareth Nahi, MD PhD, Pekka Anttila, MD, Perttu Koskenvesa, MD, Juha Lievonen, MD, Anu Marttila, MD, Ville Varmavuo, MD PhD, Anu Sikiö, MD, Marita Nurmi, MD, Marjaana Säily, MD PhD, Anu Partanen, MD PhD, Marja Sankelo, MDPhD, Sini Luoma, MD, Pentti Mäntymaa, MD PhD, Sorella Ilveskero, MD PhD, Henrik Rode Eshoj, PhD, Lene Kongsgaard Nielsen, MD PhD, Esa Jantunen, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-138447
Published: 2020
Journal Articles

Associations between Microrna Expression, Disease Progression and Ex Vivo Drug Response in Multiple Myeloma

Romika Kumari, PhD, Ashwini Kumar, MRes, Alun Parsons, Minna Suvela, MSC, Juha Lievonen, MD, Raija Helena Silvennoinen, MD PhD, Pekka Anttila, MD, Caroline A Heckman, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3069.
https://doi.org/10.1182/blood-2019-128181
Published: 2019
Journal Articles

A Phase 2 Study of Carfilzomib Plus Elotuzumab Plus Dexamethasone for Myeloma Patients Relapsed after 1-3 Prior Treatment Lines

Raija Helena Silvennoinen, MDPhD, Dimitrios Tsallos, BSc(Hons),MSc, Hareth Nahi, MD PhD, Pekka Anttila, MD, Perttu Koskenvesa, MD, Juha Lievonen, MD, Anu Räsänen, MD, Ville Varmavuo, MD PhD, Anu Sikiö, MD, Marita Nurmi, MD, Marjaana Säily, MD PhD, Anu Partanen, MD, Marja Sankelo, MDPhD, Sini Luoma, MD, Sorella Ilveskero, MD PhD, Tarja-Terttu Pelliniemi, MD PhD, Esa Jantunen, MD PhD, Muntasir M Majumder, MSc, BPharm, Samuli Eldfors, PhD, Maija Leppä, MSc(Tech), Caroline A Heckman, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1975.
https://doi.org/10.1182/blood-2018-99-114593
Published: 2018
Journal Articles

Midostaurin Shows Efficacy in Refractory Multiple Myeloma with TP53 Mutation and Elevated Expression of NTRK1, NTRK3 and AURKA

Muntasir M Majumder, MSc, BPharm, David Tamborero, PhD, Pekka Anttila, Raija Helena Silvennoinen, MD, Samuli Eldfors, MSc, Juha Lievonen, Ashwini Kumar, MRes, Alun Parsons, Minna Suvela, MSC, Esa Jantunen, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4412.
https://doi.org/10.1182/blood.V130.Suppl_1.4412.4412
Published: 2017
Journal Articles

DNA Damage Repair Pathway Alterations in Multiple Myeloma Predict Poor Prognosis, but Correlate with Sensitivity to IGF1R-PI3K-mTOR and HDAC Inhibitors

Muntasir M Majumder, MSc, MPharm, David Tamborero, PhD, Pekka Anttila, MD, Raija Silvennoinen, MD, Samuli Eldfors, MSc, Ashwini Kumar, MSc, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, Esa Jantunen, MD PhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2016) 128 (22): 198.
https://doi.org/10.1182/blood.V128.22.198.198
Published: 2016
Journal Articles

RVD + ASCT + Lenalidomide Maintenance Benefits Patients without High-Risk Cytogenetics and Results in Recovery of the Normal Plasma Cell Composition in Bone Marrow

Raija Silvennoinen, MD, Pekka Anttila, MD, Marjaana Säily, MD PhD, Tuija Lundan, PhD, Jouni Heiskanen, MD, Timo Siitonen, MD PhD, Sakari Kakko, MD PhD, Mervi Putkonen, MDPhD, Hanna Ollikainen, MD, Venla Terävä, MD, Anu Partanen, MD, Kirsi Launonen, MD, Anu Räsänen, MD, Anu Sikiö, MD, Merja Suominen, MD, Piotr Bazia, MD, Kristiina Kananen, MD PhD, Juha Lievonen, MD, Tuomas Selander, MSc, Imre Västrik, Dr, PhD, Tarja-Terttu Pelliniemi, MD PhD, Kimmo Porkka, MD PhD, Kari Remes, MD PhD, Esa Jantunen, MD PhD
Journal: Blood
Blood (2016) 128 (22): 676.
https://doi.org/10.1182/blood.V128.22.676.676
Published: 2016
Journal Articles

Stratification of Multiple Myeloma Patients Based on Ex Vivo Drug Sensitivity and Identification of New Treatments for Patients with High-Risk Relapsed/Refractory Disease

Muntasir Mamun Majumder, MSc,MPharm, Raija Silvennoinen, MD, Pekka Anttila, MD, David Tamborero, PhD, Samuli Eldfors, MSc, Juha Lievonen, MD, Riikka J Karjalainen, Heikki Kuusanmäki, MSc, Alun Parsons, Minna Suvela, Kimmo Porkka, MD PhD, Caroline Heckman
Journal: Blood
Blood (2015) 126 (23): 3006.
https://doi.org/10.1182/blood.V126.23.3006.3006
Published: 2015
Journal Articles

Identification of Dual PI3K/mTOR and BCL2 Inhibitors for the Treatment of High Risk Multiple Myeloma

Raija Silvennoinen, MD, Muntasir Mamun Majumder, MSc,BPharm, David Tamborero, PhD, Pekka Anttila, MD, Samuli Eldfors, MSc, Riikka Karjalainen, MSc, Heikki Kuusanmäki, MSc, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, Marjaana Säily, MDPhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 646.
https://doi.org/10.1182/blood.V124.21.646.646
Published: 2014
Journal Articles

Integration of Ex Vivo Drug Testing and in-Depth Molecular Profiling Reveals Oncogenic Signaling Pathways and Novel Therapeutic Strategies for Multiple Myeloma

Muntasir Mamun Majumder, MSc,BPharm, Raija Silvennoinen, MD, Pekka Antilla, David Tamborero, Samuli Eldfors, MSc, Riikka Karjalainen, MSc, Heikki Kuusanmäki, MSc, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, Marjanna Säily, Bhagwan Yadav, MSc, Krister Wennerberg, PhD, Olli Kallioniemi, MD PhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 2046.
https://doi.org/10.1182/blood.V124.21.2046.2046
Published: 2014
Journal Articles

Landscape of Driver Lesions in Multiple Myeloma and Consequences for Targeted Drug Response

David Tamborero, PhD, Muntasir Mamun Majumder, MSc,BPharm, Raija Silvennoinen, MD, Samuli Eldfors, MSc, Pekka Anttila, MD, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, BSc, Marjanna Säily, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 3351.
https://doi.org/10.1182/blood.V124.21.3351.3351
Published: 2014