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Joshua Gustine, MPH
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Journal Articles

Clinical and Genomic Factors Are Predictive of Response and Prognostic of Progression-Free Survival in Patients with Waldenström Macroglobulinemia Treated with Ibrutinib

Jorge J. Castillo, MD, Joshua Gustine, MPH, Maria Demos, Andrew Keezer, BS, Kirsten Meid, MPH, Gloria G Chan, MS, Jiaji G Chen, Maria Luisa Guerrera, MD, Amanda Kofides, Manit Munshi, MS, Nicholas Tsakmaklis, Xia Liu, MD, Lian Xu, MS, Guang Yang, PhD, Zachary R Hunter, PhD, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 2823.
https://doi.org/10.1182/blood-2019-125069
Published: 2019
Journal Articles

CXCR4 Mutational Status Does Not Impact Outcomes in Patients with Waldenstrom Macroglobulinemia Treated with Proteasome Inhibitors

Jorge J. Castillo, MD, Joshua Gustine, MPH, Maria Demos, Andrew Keezer, BS, Kirsten Meid, MPH, Toni Dubeau, NP, Gloria G Chan, MS, Jiaji Chen, BS, Maria Luisa Guerrera, MD, Amanda Kofides, Manit Munshi, MS, Nicholas Tsakmaklis, Xia Liu, MD, Lian Xu, MS, Guang Yang, PhD, Zachary R Hunter, PhD, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 2830.
https://doi.org/10.1182/blood-2019-122349
Published: 2019
Journal Articles

MYD88 Triggered SYK Activation Promotes BCR Cross-Talk, and Identifies SYK As a Novel Therapeutic Target of Mutated MYD88 Signaling

Manit Munshi, MS, Jiaji Chen, BS, Xia Liu, MD, Lian Xu, MS, Nickolas Tsakmaklis, BA, Maria Demos, Amanda Kofides, Maria Luisa Guerrera, MD, Gloria G Chan, MS, Christopher Patterson, MAcc, Kirsten Meid, MPH, Joshua Gustine, MPH, Jorge J. Castillo, MD, Zachary R Hunter, PhD, Jinhua Wang, PhD, Sara J Buhrlage, PhD, Nathanael S. Gray, PhD, Steven P Treon, MD PhD FRCP, Guang Yang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4116.
https://doi.org/10.1182/blood-2018-99-117372
Published: 2018
Journal Articles

Genomic Analysis of Ibrutinib Resistance in Waldenstrom Macroglobulinemia

Cristina Jimenez, PhD, Gloria G Chan, MS, Lian Xu, MS, Nickolas Tsakmaklis, Jiaji G Chen, Maria Demos, Amanda Kofides, Maria Luisa Guerrera, MD, Xia Liu, MD, Manit Munshi, MS, Joshua Gustine, MPH, Guang Yang, PhD, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Zachary R Hunter, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1372.
https://doi.org/10.1182/blood-2018-99-118819
Published: 2018
Journal Articles

Deepening of Response after Completing Rituximab-Containing Primary Therapy in Patients with Waldenstrom Macroglobulinemia

Jorge J. Castillo, MD, Joshua Gustine, MPH, Toni Dubeau, NP, Kirsten Meid, MPH, Andrew Keezer, BS, Lian Xu, MS, Guang Yang, PhD, Zachary R Hunter, PhD, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 2887.
https://doi.org/10.1182/blood-2018-99-110675
Published: 2018
Journal Articles

Multicenter Prospective Phase II Study of Venetoclax in Patients with Previously Treated Waldenstrom Macroglobulinemia

Jorge J. Castillo, MD, Joshua Gustine, MPH, Kirsten Meid, MPH, Toni Dubeau, NP, Andrew Keezer, BS, John N. Allan, MD, Richard R. Furman, MD, Tanya Siddiqi, MD, Ranjana Advani, MD, Jessica Lam, Zachary R Hunter, PhD, Guang Yang, PhD, Lian Xu, MS, Matthew S Davids, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 2888.
https://doi.org/10.1182/blood-2018-99-112325
Published: 2018
Journal Articles

Ibrutinib Dose Reduction Does Not Affect Progression-Free Survival in Patients with Waldenstrom Macroglobulinemia

Jorge J. Castillo, MD, Joshua Gustine, MPH, Andrew Keezer, BS, Kirsten Meid, MPH, Toni Dubeau, NP, Lian Xu, MS, Guang Yang, PhD, Zachary R Hunter, PhD, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 1598.
https://doi.org/10.1182/blood-2018-99-111626
Published: 2018
Journal Articles

Alternative Mutations and Isoform Dysregulation in MYD88 in Waldenstrom's Macroglobulinemia

Amanda Kofides, Maria Demos, Nickolas Tsakmaklis, Lian Xu, MS, Xia Liu, MD, Christopher Patterson, Maria Luisa Guerrera, MD, Manit Munshi, MS, Guang Yang, PhD, Jiaji G Chen, Cristina Jimenez, PhD, Gloria G Chan, MS, Joshua Gustine, MPH, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Zachary R Hunter, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1566.
https://doi.org/10.1182/blood-2018-99-119419
Published: 2018
Journal Articles

Molecular Basis of Ibrutinib Resistance in Waldenstrom's Macroglobulinemia

Lian Xu, Nicholas Tsakmaklis, Guang Yang, PhD, Jiaji G Chen, Xia Liu, MD, Jie Chen, PhD, Maria Demos, Christopher J Patterson, MFA, Toni Dubeau, NP, Kirsten Meid, MPH, Joshua Gustine, MPH, Jorge J. Castillo, MD, Ranjana H Advani, MD, Maria Lia Palomba, MD, Richard R. Furman, MD, Zachary Hunter, PhD, Steven P Treon, MD PhD
Journal: Blood
Blood (2016) 128 (22): 756.
https://doi.org/10.1182/blood.V128.22.756.756
Published: 2016
Journal Articles

IgM Myeloma: A Multicenter Retrospective Study of 159 Patients

Jorge J. Castillo, MD, Artur J. Jurczyszyn, MD PhD, Edvan Crusoe, MD MsC, Jacek Czepiel, MD, Julio Davila, MD, Angela Dispenzieri, MD, Marion Eveillard, PharmD, PhD, Mark A Fiala, BS, CCRP, Irene M. Ghobrial, MD, Alessandro Gozzetti, MD, Joshua Gustine, MPH, Roman Hájek, Vânia Hungria, MD PhD, Jiri Jarkovsky, MSc, PhD, David Jayabalan, BSMS, MSc, Jacob P. Laubach, MD, Barbara Lewicka, MD, Vladimir Maisnar, MD PhD, Elisabeth E. Manasanch, MD, Philippe Moreau, MD, Hareth Nahi, Ruben Niesvizky, MD, Claudia E. Paba-Prada, MD, Tomas Pika, MD PhD, Ludek Pour, MD PhD, John L Reagan, MD, Paul G Richardson, MD, Jatin J. Shah, MD, Ivan Spicka, MDPhD, Ravi Vij, MD, Anna Waszczuk, MD PhD, Morie A. Gertz, MD MACP
Journal: Blood
Blood (2016) 128 (22): 3276.
https://doi.org/10.1182/blood.V128.22.3276.3276
Published: 2016
Journal Articles

Ixazomib, Dexamethasone and Rituximab in Previously Untreated Patients with Waldenström Macroglobulinemia

Jorge J. Castillo, MD, Joshua Gustine, MPH, Kirsten Meid, MPH, Toni Dubeau, NP, Guang Yang, PhD, Lian Xu, Zachary Hunter, PhD, Steven P Treon, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2956.
https://doi.org/10.1182/blood.V128.22.2956.2956
Published: 2016
Journal Articles

Prospective, Multicenter Clinical Trial of Everolimus As Primary Therapy in Waldenstrom Macroglobulinemia (WMCTG 09-214)

Steven P Treon, MD PhD, Kirsten Meid, MPH, Christina K. Tripsas, MA, Leonard T. Heffner, MD, Herbert Eradat, Ashraf Z Badros, MD, Lian Xu, Zachary Hunter, PhD, Guang Yang, PhD, Christopher J Patterson, MFA, Joshua Gustine, MPH, Jorge J. Castillo, MD, Jeffrey V. Matous, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2016) 128 (22): 4487.
https://doi.org/10.1182/blood.V128.22.4487.4487
Published: 2016
Journal Articles

Lower Doses of Bendamustine Are Not Associated with Lower Response Rates in Previously Untreated Patients with Waldenström Macroglobulinemia

Jorge J. Castillo, MD, Joshua Gustine, MPH, Kirsten Meid, MPH, Toni Dubeau, NP, Irene M. Ghobrial, MD, Steven P Treon, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2969.
https://doi.org/10.1182/blood.V128.22.2969.2969
Published: 2016
Journal Articles

The High Risk for Symptomatic Hyperviscosity in Patients with High Serum IgM Levels Can be Used to Support Initiation of Treatment in Waldenström Macroglobulinemia

Joshua Gustine, MPH, Kirsten Meid, MPH, Robert R Manning, Toni Dubeau, NP, Irene M. Ghobrial, MD, Steven P Treon, MD PhD, Jorge J. Castillo, MD
Journal: Blood
Blood (2016) 128 (22): 2983.
https://doi.org/10.1182/blood.V128.22.2983.2983
Published: 2016
Journal Articles

Mutated MYD88 Zygosity and CXCR4 Mutation Status Are Important Determinants of Ibrutinib Response and Progression Free Survival in Waldenstrom's Macroglobulinemia

Steven P Treon, MD PhD, Nicholas Tsakmaklis, Kirsten Meid, MPH, Guang Yang, PhD, Jiaji G Chen, Xia Liu, MD, Jie Chen, PhD, Maria Demos, Christopher J Patterson, MFA, Toni Dubeau, NP, Joshua Gustine, MPH, Jorge J. Castillo, MD, Ranjana H Advani, MD, Maria Lia Palomba, MD, Lian Xu, Zachary Hunter, PhD
Journal: Blood
Blood (2016) 128 (22): 2984.
https://doi.org/10.1182/blood.V128.22.2984.2984
Published: 2016
Journal Articles

Long-Term Outcome of a Prospective Study of Bortezomib, Dexamethasone and Rituximab (BDR) in Previously Untreated, Symptomatic Patients with Waldenstrom's Macroglobulinemia

Steven P Treon, MD PhD, Kirsten Meid, MPH, Joshua Gustine, MPH, Christopher J Patterson, MFA, Jeffrey V. Matous, MD, Irene M. Ghobrial, MD, Jorge J Castillo, MD
Journal: Blood
Blood (2015) 126 (23): 1833.
https://doi.org/10.1182/blood.V126.23.1833.1833
Published: 2015
Journal Articles

Defining the Incidence, Pathology and Clinical Outcomes of Kidney Disease Related to Waldenstrom's Macroglobulinemia and IgM MGUS

Josephine M. Vos, MD, Robert R Manning, Kirsten Meid, MPH, Joshua Gustine, MPH, Christopher J Patterson, MFA, Philip Brodsky, Sandra Kanan, NP, RN, MSN, Marie José Kersten, MD PhD, Steven P Treon, MD PhD, Jorge J Castillo, MD
Journal: Blood
Blood (2015) 126 (23): 3926.
https://doi.org/10.1182/blood.V126.23.3926.3926
Published: 2015