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Journal Articles

The Internal Ribosome Entry Site-Medaited Expression of VEGF Rescues HS Sultan Tumor Cells From Mammalian Target of Rapamycin (mTOR)-Inhibitors Induced Apoptosis in Vivo

Patrick Frost, Joseph Gera, Alan K. Lichtenstein, M.D.
Journal: Blood
Blood (2012) 120 (21): 1659.
https://doi.org/10.1182/blood.V120.21.1659.1659
Published: 2012
Journal Articles

Targeting Deptor in Multiple Myeloma

Yonghui Yang, Joseph Gera, Alan Lichtenstein, MD
Journal: Blood
Blood (2012) 120 (21): 575.
https://doi.org/10.1182/blood.V120.21.575.575
Published: 2012
Journal Articles

Identification and Characterization of Inhibitors That Specifically Target TORC2 in Multiple Myeloma

Bao Hoang, Joseph Gera, Alan Lichtenstein, MD
Journal: Blood
Blood (2012) 120 (21): 5026.
https://doi.org/10.1182/blood.V120.21.5026.5026
Published: 2012
Journal Articles

Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor

Bao Hoang, Patrick Frost, Yijiang Shi, Eileen Belanger, Angelica Benavides, Gholam Pezeshkpour, Susanna Cappia, Tommasina Guglielmelli, Joseph Gera, Alan Lichtenstein
Journal: Blood
Blood (2010) 116 (22): 4560–4568.
https://doi.org/10.1182/blood-2010-05-285726
Published: 2010
Includes: Supplemental data
Journal Articles

Interleukin-6 (IL-6) Enhances C-MYC Translation IN MULTIPLE MYELOMA (MM) CELLS: ROLE of IL-6-INDUCED EFFECTS On the C-MYC RNA-Binding PROTEIN, HNRNPA1.

Yijiang Shi, Joseph Gera, Alan Lichtenstein, MD
Journal: Blood
Blood (2009) 114 (22): 3839.
https://doi.org/10.1182/blood.V114.22.3839.3839
Published: 2009
Journal Articles

IL-6 Enhances C-myc Translation in Myeloma Cells Via Activation of the Myc Internal Ribosomal Entry Site (IRES) and an IRES-Binding Trans Factor, hnRNP A1.

Yijiang Shi, Joseph Gera, Alan Lichtenstein
Journal: Blood
Blood (2007) 110 (11): 3514.
https://doi.org/10.1182/blood.V110.11.3514.3514
Published: 2007
Journal Articles

Mechanism by Which mTOR Inhibitors Sesitize Multiple Myeloma Cells to Dexamethasone-Induced Apoptosis.

Huajun Yan, PhD, Patrick Frost, PhD, Yijiang Shi, MD & PhD, Bao Hoang, PhD, Sanjai Sharma, MD, Myrna Fisher, Joseph Gera, PhD, Alan Lichtenstein, MD
Journal: Blood
Blood (2005) 106 (11): 1582.
https://doi.org/10.1182/blood.V106.11.1582.1582
Published: 2005
Journal Articles

In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model

Patrick Frost, Farhad Moatamed, Bao Hoang, Yijiang Shi, Joseph Gera, Huajun Yan, Philip Frost, Jay Gibbons, Alan Lichtenstein
Journal: Blood
Blood (2004) 104 (13): 4181–4187.
https://doi.org/10.1182/blood-2004-03-1153
Published: 2004
Journal Articles

AKT Activity Regulates Sensitivity of Multiple Myeloma Cells to mTor Inhibitors.

Patrick Frost, Ph.D., Bao Hoang, Ph.D., Joseph Gera, Ph.D., Anushree Sharma, Yijiang Shi, Ph.D., Huajun Yan, Ph.D., Alan Lichtenstein, MD.
Journal: Blood
Blood (2004) 104 (11): 646.
https://doi.org/10.1182/blood.V104.11.646.646
Published: 2004
Journal Articles

MTOR Inhibitors Activate the AKT Kinase in Multiple Myeloma Cells by Upregulating the IGF-1/IRS-1/PI-3 Kinase Cascade.

Yijiang Shi, Ph D, HuaJun Yan, Ph D, Patrick Frost, Ph D, Bao Hoang, Ph D, Joseph Gera, Ph D, Alan Lichtenstein, MD
Journal: Blood
Blood (2004) 104 (11): 3350.
https://doi.org/10.1182/blood.V104.11.3350.3350
Published: 2004
Journal Articles

Downstream effectors of oncogenic ras in multiple myeloma cells

Liping Hu, Yijiang Shi, Jung-hsin Hsu, Joseph Gera, Brian Van Ness, Alan Lichtenstein
Journal: Blood
Blood (2003) 101 (8): 3126–3135.
https://doi.org/10.1182/blood-2002-08-2640
Published: 2003