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Journal Articles

AKT Kinase Addiction in Multiple Myeloma.

Carolyne Bardeleben, PhD, Huajun Yan, PhD, Patrick Frost, PhD, Bao Hoang, PhD, Yijiang Shi, MD, PhD, Sanjai Sharma, MD, Alan Lichtenstein, MD
Journal: Blood
Blood (2006) 108 (11): 3431.
https://doi.org/10.1182/blood.V108.11.3431.3431
Published: 2006
Journal Articles

Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance

Bao Hoang, Li Zhu, Yijiang Shi, Patrick Frost, Huajun Yan, Sanjai Sharma, Sherven Sharma, Lee Goodglick, Steven Dubinett, Alan Lichtenstein
Journal: Blood
Blood (2006) 107 (11): 4484–4490.
https://doi.org/10.1182/blood-2005-09-3926
Published: 2006
Journal Articles

Anti-Angiongenic Effects of mTOR-Inhibitors Is Regulated by AKT Activity in Multiple Myeloma Cells.

Patrick Frost, PhD, Bao Hoang, PhD, Yijiang Shi, MD, Huajun Yan, PhD, Alan Lichtenstein, MD
Journal: Blood
Blood (2005) 106 (11): 3406.
https://doi.org/10.1182/blood.V106.11.3406.3406
Published: 2005
Journal Articles

Mechanism by Which mTOR Inhibitors Sesitize Multiple Myeloma Cells to Dexamethasone-Induced Apoptosis.

Huajun Yan, PhD, Patrick Frost, PhD, Yijiang Shi, MD & PhD, Bao Hoang, PhD, Sanjai Sharma, MD, Myrna Fisher, Joseph Gera, PhD, Alan Lichtenstein, MD
Journal: Blood
Blood (2005) 106 (11): 1582.
https://doi.org/10.1182/blood.V106.11.1582.1582
Published: 2005
Journal Articles

In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model

Patrick Frost, Farhad Moatamed, Bao Hoang, Yijiang Shi, Joseph Gera, Huajun Yan, Philip Frost, Jay Gibbons, Alan Lichtenstein
Journal: Blood
Blood (2004) 104 (13): 4181–4187.
https://doi.org/10.1182/blood-2004-03-1153
Published: 2004
Journal Articles

MTOR Inhibitors Activate the AKT Kinase in Multiple Myeloma Cells by Upregulating the IGF-1/IRS-1/PI-3 Kinase Cascade.

Yijiang Shi, Ph D, HuaJun Yan, Ph D, Patrick Frost, Ph D, Bao Hoang, Ph D, Joseph Gera, Ph D, Alan Lichtenstein, MD
Journal: Blood
Blood (2004) 104 (11): 3350.
https://doi.org/10.1182/blood.V104.11.3350.3350
Published: 2004
Journal Articles

AKT Activity Regulates Sensitivity of Multiple Myeloma Cells to mTor Inhibitors.

Patrick Frost, Ph.D., Bao Hoang, Ph.D., Joseph Gera, Ph.D., Anushree Sharma, Yijiang Shi, Ph.D., Huajun Yan, Ph.D., Alan Lichtenstein, MD.
Journal: Blood
Blood (2004) 104 (11): 646.
https://doi.org/10.1182/blood.V104.11.646.646
Published: 2004