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Journal Articles

A 9-Gene Expression Signature Identifies Patients with Core-Binding Factor Acute Myeloid Leukemia at High Risk of Relapse after Achieving Complete Remission

Guillaume Richard-Carpentier, MD, Miriam Marquis, PhD, Francois Beliveau, PhD, Guy Sauvageau, MD PhD, Josee Hebert, MD

Blood (2019) 134 (Supplement_1): 1432.

https://doi.org/10.1182/blood-2019-129990

Published: 2019

Journal Articles

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 910.

https://doi.org/10.1182/blood-2018-99-114525

Published: 2018

Journal Articles

Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression

Céline Moison, PhD, Vincent-Philippe Lavallee, MD, Clarisse Thiollier, PhD, Jean-Francois Spinella, PhD, Isabel Boivin, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 3925.

https://doi.org/10.1182/blood-2018-99-111304

Published: 2018

Journal Articles

Apoptotic Blocks in Primary Non-Hodgkin B-Cell Lymphomas Identified By BH3 Profiling

Nathalie A Johnson, MD PhD, Claudia M Wever, PhD, Dominique Geoffrion, BSc, Ghassemian Artin, MD, Brailovski Eugene, Pierre Sesques, MD, Jeremy A. Ryan, SM, Liliana Stoica, Josee Hebert, MD, Tina Petrogiannis-Haliotis, MD PhD, Svetlana Dmitrienko, MD PhD, Frenkiel Saul, MD, German Ott, MD, Annette Staiger, Christian Steidl, MD, David W. Scott, PhD MD, FRACP, FRCPA, Koren Kathleen Mann, PhD, Anthony Letai, MD PhD

Blood (2018) 132 (Supplement 1): 4126.

https://doi.org/10.1182/blood-2018-99-118225

Published: 2018

Journal Articles

High Expression of SPAG1 Is Associated with a Worse Clinical Outcome in Intermediate Risk Acute Myeloid Leukemia That Can be Partially Overcome By Hematopoietic Stem Cell Transplantation

Guillaume Richard-Carpentier, MD, Miriam Marquis, PhD, Guy Sauvageau, MD, PhD, Josee Hebert, MD

Blood (2018) 132 (Supplement 1): 2804.

https://doi.org/10.1182/blood-2018-99-113918

Published: 2018

Journal Articles

Genetic Characterization of ABT-199 Sensitivity in Human AML

Marie-Eve Bordeleau, PhD, Richard Bisaillon, PhD, Clarisse Thiollier, PhD, Jana Krosl, PhD, Bernhard Lehnertz, PhD, Vincent-Philippe Lavallee, MD, Tara MacRae, Labelle Caroline, Geneviève Boucher, Isabel Boivin, Giovanni D'Angelo, Sylvie Lavallée, Anne Marinier, PhD, Sébastien Lemieux, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 283.

https://doi.org/10.1182/blood-2018-99-113062

Published: 2018

Journal Articles

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Laura Simon, BSc, MSc, Vincent-Philippe Lavallee, MD, Marie-Eve Bordeleau, PhD, Bernhard Lehnertz, PhD, Tara MacRae, Jalila Chagraoui, PhD, Jean-Francois Spinella, PhD, Geneviève Boucher, Thierry Bertomeu, PhD, Jasmin Coulombe-Huntington, PhD, Mike Tyers, PhD, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD PhD

Blood (2018) 132 (Supplement 1): 4675.

https://doi.org/10.1182/blood-2018-99-111030

Published: 2018

Journal Articles

Reduced Intensity Conditioned Sibling Transplantation Versus No Transplant in Intermediate or High Risk Acute Myeloid Leukemia: A Prospective Multi-Center Study in Patients 50-70 Years in First Complete Remission and with at Least One Potential Sibling Donor ( ClinTrialGov 00342316 )

Mats Brune, MD PhD, Thomas L. Kiss, MD, Elisabeth Wallhult, RN, Harald Anderson, PhD, Robert Delage, MD, Jürgen Finke, MD, Josee Hebert, MD, Martin Höglund, MD PhD, Ain Kaare, MD, Vladimir Lazarevic, MD PhD, Malin Nicklasson, MSc, Kari Remes, MD PhD, David Ritchie, MBChB, PhD FRACP, FRCPA, Mitchell Sabloff, MD, Ruth Spearing, MD, Alexandros Spyridonidis, MD PhD, Jeffrey Szer, MBBS, Per Ljungman, MD PhD

Blood (2018) 132 (Supplement 1): 205.

https://doi.org/10.1182/blood-2018-99-110260

Published: 2018

Journal Articles

Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias

Vincent-Philippe Lavallee, MD, Jalila Chagraoui, PhD, MacRae Tara, M.Sc., Miriam Marquis, PhD, Bonnefoy Arnaud, PhD, Jana Krosl, PhD, Sébastien Lemieux, PhD, Georges-Étienne Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 105.

https://doi.org/10.1182/blood.V130.Suppl_1.105.105

Published: 2017

Journal Articles

HMGA2 Gene Expression Profile Improves Risk Stratification in Acute Myeloid Leukemia

Miriam Marquis, PhD, Cyrielle Beaubois, Vincent-Philippe Lavallee, MD, Michal Abrahamowicz, PhD, Coraline Danieli, PhD, Sébastien Lemieux, PhD, Imran Ahmad, MD, Andrew Wei, MBBS, FRACP, FRCPA, PhD, Stephen B Ting, MD PhD, Shaun Fleming, MBBS(Hons) FRACP FRCPA, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, William Grey, PhD, David Grimwade, MD PhD, Robert K. Hills, DPhil, Paresh Vyas, MD PhD, Nigel H. Russell, MD, Guy Sauvageau, MD, PhD, Josee Hebert, MD

Blood (2017) 130 (Supplement 1): 1402.

https://doi.org/10.1182/blood.V130.Suppl_1.1402.1402

Published: 2017

Journal Articles

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Bernhard Lehnertz, PhD, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Tomellini Elisa, PhD, Jalila Chagraoui, PhD, Vincent-Philippe Lavallée, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 302.

https://doi.org/10.1182/blood.V130.Suppl_1.302.302

Published: 2017

Journal Articles

Understanding Apoptotic Blocks in "Double Hit" and Other Non-Hodgkin Lymphomas By BH3 Profiling

Claudia M Wever, PhD, Dominique Geoffrion, BSc, Pierre Sesques, MD, Liliana Stoica, Josee Hebert, MD, Jeremy Ryan, Anthony Letai, MD PhD, Nathalie A Johnson, MDPhD

Blood (2017) 130 (Supplement 1): 1471.

https://doi.org/10.1182/blood.V130.Suppl_1.1471.1471

Published: 2017

Journal Articles

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Vincent-Philippe Lavallée, MD, Miriam Marquis, PhD, Marie-Ève Bordeleau, PhD, Jalila Chagraoui, PhD, Tara MacRae, M.Sc., Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Arnaud Bonnefoy, PhD, Georges E. Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 1075.

https://doi.org/10.1182/blood.V128.22.1075.1075

Published: 2016

Journal Articles

Targeting Pre-Leukemic Stem Cells in T-Acute Lymphoblastic Leukemia

Blood (2016) 128 (22): 527.

https://doi.org/10.1182/blood.V128.22.527.527

Published: 2016

Journal Articles

Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1

Vincent-Philippe Lavallée, MD, Clarisse Thiollier, PhD, Céline Moison, PhD, Marie-Ève Bordeleau, PhD, Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 769.

https://doi.org/10.1182/blood.V128.22.769.769

Published: 2016

Journal Articles

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

Sophie Cardin, PhD, Louise Laramee, Tara MacRae, M.Sc., Jalila Chagraoui, PhD, Guy Sauvageau, MD PhD, R. Keith Humphries, MD PhD, Josée Hébert, MD, Brian T. Wilhelm, PhD, Sonia Cellot, MD PhD

Blood (2016) 128 (22): 1535.

https://doi.org/10.1182/blood.V128.22.1535.1535

Published: 2016

Journal Articles

The Novel Leukemia Stem Cell Marker GPR56 Discriminates Leukemic Subclones with Divergent Stem Cell Properties in Human Acute Myeloid Leukemia

Caroline Pabst, MD, Anne Bergeron, PhD, Vincent-Philippe Lavallée, MD, Jonathan Yeh, PhD, Patrick Gendron, M.Sc, Jana Krosl, PhD, Geneviève Boucher, M.Sc, Sébastien Lemieux, PhD, Josee Hébert, MD, Guy Sauvageau, MD, PhD, Frédéric Barabé, MD

Blood (2015) 126 (23): 1859.

https://doi.org/10.1182/blood.V126.23.1859.1859

Published: 2015

Journal Articles

Transcriptome Analysis Reveals That G Protein-Coupled Receptors Are Potential Diagnostic Markers or Therapeutic Targets in Acute Myeloid Leukemia

Arhamatoulaye Maiga, PhD, Sébastien Lemieux, PhD, Caroline Pabst, MD, Vincent-Philippe Lavallée, MD, Michel Bouvier, PhD, Guy Sauvageau, MD, PhD, Josée Hébert, MD

Blood (2015) 126 (23): 3855.

https://doi.org/10.1182/blood.V126.23.3855.3855

Published: 2015

Journal Articles

Mutational and Transcriptomic Landscape of AML with Core-Binding Factor Rearrangements

Vincent-Philippe Lavallée, MD, Patrick Gendron, M.Sc, Geneviève Boucher, M.Sc, Sébastien Lemieux, PhD, Richard Neil Armstrong, PhD, Isabel Boivin, M.Sc, Guy Sauvageau, MD, PhD, Josée Hébert, MD

Blood (2015) 126 (23): 802.

https://doi.org/10.1182/blood.V126.23.802.802

Published: 2015

Journal Articles

Novel Targeting Strategies for Leukemia-Initiating Cells in Myeloid Neoplasms

Guy Sauvageau, MD, PhD, Caroline Pabst, MD, Sebastien Lemieux, PhD, Josée Hébert, MD, Jana Krosl, phD

Blood (2013) 122 (21): SCI-27.

https://doi.org/10.1182/blood.V122.21.SCI-27.SCI-27

Published: 2013

NARROW

A 9-Gene Expression Signature Identifies Patients with Core-Binding Factor Acute Myeloid Leukemia at High Risk of Relapse after Achieving Complete Remission

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression

Apoptotic Blocks in Primary Non-Hodgkin B-Cell Lymphomas Identified By BH3 Profiling

High Expression of SPAG1 Is Associated with a Worse Clinical Outcome in Intermediate Risk Acute Myeloid Leukemia That Can be Partially Overcome By Hematopoietic Stem Cell Transplantation

Genetic Characterization of ABT-199 Sensitivity in Human AML

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Reduced Intensity Conditioned Sibling Transplantation Versus No Transplant in Intermediate or High Risk Acute Myeloid Leukemia: A Prospective Multi-Center Study in Patients 50-70 Years in First Complete Remission and with at Least One Potential Sibling Donor ( ClinTrialGov 00342316 )

Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias

HMGA2 Gene Expression Profile Improves Risk Stratification in Acute Myeloid Leukemia

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Understanding Apoptotic Blocks in "Double Hit" and Other Non-Hodgkin Lymphomas By BH3 Profiling

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Targeting Pre-Leukemic Stem Cells in T-Acute Lymphoblastic Leukemia

Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

The Novel Leukemia Stem Cell Marker GPR56 Discriminates Leukemic Subclones with Divergent Stem Cell Properties in Human Acute Myeloid Leukemia

Transcriptome Analysis Reveals That G Protein-Coupled Receptors Are Potential Diagnostic Markers or Therapeutic Targets in Acute Myeloid Leukemia

Mutational and Transcriptomic Landscape of AML with Core-Binding Factor Rearrangements

Novel Targeting Strategies for Leukemia-Initiating Cells in Myeloid Neoplasms

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American Society of Hematology

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