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Johannes Zuber, MD
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Journal Articles

Uncovering Key Downstream Effectors of PU.1 Tumor Suppression in Acute Myeloid Leukemia

Margherita Ghisi, PhD, Mark D McKenzie, PhD, Ethan P Oxley, Emilia Simankowicz, Cynthia Liu, Aleksandar Dakic, PhD, Stephen L Nutt, PhD, Matthew E Ritchie, PhD, Johannes Zuber, MD PhD, Ross A Dickins, PhD
Journal: Blood
Blood (2016) 128 (22): 2698.
https://doi.org/10.1182/blood.V128.22.2698.2698
Published: 2016
Journal Articles

The Transcription Factor PU.1 Controls a Reversible Differentiation Program in Acute Myeloid Leukemia

Mark D McKenzie, PhD, Margherita Ghisi, PhD, Luisa Cimmino, PhD, Michael Erlichster, Ethan P Oxley, Cynthia Liu, Matthew T Witkowski, PhD, Grace Liu, PhD, Aleksandar Dakic, PhD, Emilia Simankowicz, Ladina DiRago, Donald Metcalf, MD, Stephen L Nutt, PhD, Meaghan Wall, MBBS, PhD FRACP, FRCPA, Matthew E Ritchie, PhD, Johannes Zuber, MD PhD, Ross A Dickins, PhD
Journal: Blood
Blood (2016) 128 (22): 3930.
https://doi.org/10.1182/blood.V128.22.3930.3930
Published: 2016
Journal Articles

Effects of CCL2/CCR2 Blockade in Acute Myeloid Leukemia

Rodrigo Omar Jacamo, PhD, Hong Mu, MD PhD, Qi Zhang, Dhruv Chachad, MS, Wang Zhiqiang, Wencai Ma, PhD, Min Zhang, MD PhD, Po Yee Mak, MPhil, Duncan Mak, BSc, MPhil, Peter Ruvolo, PhD, Teresa McQueen, Scott Lowe, Johannes Zuber, MD PhD, Dirk Eulberg, MBA, Anna Kruschinski, Marina Konopleva, MD PhD, R Eric Davis, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1348.
https://doi.org/10.1182/blood.V126.23.1348.1348
Published: 2015
Journal Articles

Identification of the Epigenetic Reader BRD4 As a Novel Potential Target in Ph+ CML

Barbara Peter, DVM, Gregor Eisenwort, Gabriele Stefanzl, Daniela Berger, Wolfgang R Sperr, MD, Johannes Zuber, MD PhD, Peter Valent, MD
Journal: Blood
Blood (2015) 126 (23): 1571.
https://doi.org/10.1182/blood.V126.23.1571.1571
Published: 2015
Journal Articles

Identification of the Epigenetic Reader BRD4 As a Novel Therapeutic Target in JAK2 V617F+ MPN Cells

Alexandra Keller, MSc, Barbara Peter, DVM, Johannes Zuber, MD PhD, Philipp Bernhard Staber, MD PhD, Peter Bettelheim, MD, Peter Valent, MD, Emir Hadzijusufovic, DVM
Journal: Blood
Blood (2015) 126 (23): 2829.
https://doi.org/10.1182/blood.V126.23.2829.2829
Published: 2015
Journal Articles

Preclinical Efficacy of MEK Inhibition in Nras Mutant Acute Myeloid Leukemia

Michael R. Burgess, MD PhD, Eugene Hwang, BA, Ari J Firestone, PhD, Tannie Huang, MD, Jin Xu, PhD, Johannes Zuber, MD, Natacha Bohin, BS, Tiffany Wen, BS, Scott C. Kogan, MD, Kevin M. Haigis, PhD, Scott W. Lowe, PhD, Kevin Shannon, MD, Qing Li, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3753.
https://doi.org/10.1182/blood.V124.21.3753.3753
Published: 2014
Journal Articles

RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development

Xiaomei Yan, MD PhD, Yoshihiro Hayashi, MD PhD, Xinghui Zhao, PhD, Aili Chen, PhD, Yue Zhang, MD, Fuhong He, Yunzhu Dong, Yalan Rao, PhD, Bo Li, Rajeana Conway, Alba Maiques-Díaz, Nuomin Huang, Shannon E Elf, Johannes Zuber, MD, Zhijian Xiao, MD, William Tse, Daniel G. Tenen, MD, Qianfei Wang, Wei Chen, James C. Mulloy, PhD, Stephen D Nimer, MD, Gang Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 2187.
https://doi.org/10.1182/blood.V124.21.2187.2187
Published: 2014
Journal Articles

AML Genotype-Specific and Non-Specific Regulation of Mesenchymal Stromal Cell Transcriptome in the Bone Marrow Microenvironment

Rodrigo Jacamo, PhD, Xiaoyang Ling, PhD, Zhiqiang Wang, Wencai Ma, PhD, Min Zhang, PhD, Peter P. Ruvolo, PhD, Vivian R Ruvolo, MA, Scott W. Lowe, PhD, Johannes Zuber, MD, Marina Konopleva, MD PhD, R Eric Davis, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1586.
https://doi.org/10.1182/blood.V124.21.1586.1586
Published: 2014
Journal Articles

Investigating Synthetic Lethality Between mTOR Hyperactivation and Cap-Dependent mRNA Translation In a Receptor Tyrosine Kinase Driven Model Of Acute T-Cell Leukemia

Adrian Schwarzer, MD PhD, Helmut Holtmann, PhD, Celina Schauerte, M.Sc., Nomme Benn, Jan Völkel, Sabine Knöß, Johannes Zuber, MD, Zhixiong Li, MD, Axel Schambach, MD PhD, Christopher Baum, MD
Journal: Blood
Blood (2013) 122 (21): 3913.
https://doi.org/10.1182/blood.V122.21.3913.3913
Published: 2013
Journal Articles

Inhibition Of RNA Polymerase I Transcription By CX-5461 As a Therapeutic Strategy For The Cancer-Specific Activation Of p53 In Highly Refractory Haematological Malignancies

Nadine Hein, PhD, Sean O'Brien, Ph.D., Denis Drygin, PhD, Simon J. Harrison, MBBS MRCP (uk) MRCPath (uk) PhD, Amit Khot, MD, FRCPath, MBBS, MRCP, Carleen Cullinane, PhD, Matthews Geoff, PhD, Marta Chesi, PhD, Peter Leif Bergsagel, MD, Johannes Zuber, MD, Scott W. Lowe, Ph.D., Ricky W Johnstone, PhD, Rick Pearson, PhD, Grant A. McArthur, MD, PhD, FRACP, MBBS, Ross D Hannan, PhD
Journal: Blood
Blood (2013) 122 (21): 3941.
https://doi.org/10.1182/blood.V122.21.3941.3941
Published: 2013
Journal Articles

Bromodomain-Containing Protein 4 (BRD4): A Novel Marker and Drug Target Expressed In Neoplastic Cells In Advanced Mast Cell Neoplasms

Ghaith Wedeh, Emir Hadzijusufovic, DVM, Sabine Cerny-Reiterer, D.V.M, Harald Herrmann, M.D., Katharina Blatt, MSc, Ph.D., Gregor Eisenwort, M.D., Ph.D, Gregor Hoermann, M.D., Ph.D., Wolfgang R Sperr, M.D., Leonhard Müllauer, M.D., Christopher R. Vakoc, M.D., Ph.D., James E Bradner, MD, Hans-Peter Horny, MD, Michael Willmann, D.V.M., Johannes Zuber, MD, Michel Arock, PharmD, Ph.D, Peter Valent
Journal: Blood
Blood (2013) 122 (21): 3747.
https://doi.org/10.1182/blood.V122.21.3747.3747
Published: 2013
Journal Articles

The Flt3 ITD Accelerates An Already Established Myeloid Leukemia and Alters Chemotherapy Response In Vitro and In Vivo in a p53 Dependent Manner.

Timothy Pardee, MD, PhD, Johannes Zuber, MD, Scott Lowe, PhD
Journal: Blood
Blood (2009) 114 (22): 1719.
https://doi.org/10.1182/blood.V114.22.1719.1719
Published: 2009