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Journal Articles

Cryopreserved CAR-like NK Cells Pre-Complexed with the CD30/CD16A Bispecific Innate Cell Engager (ICE®) AFM13 for the Treatment of CD30 + Malignancies

Uwe Reusch, Kristina Ellwanger, Ivica Fucek, Thomas Müller, Ute Schniegler-Mattox, Jens Pahl, Michael Tesar, Joachim Koch
Journal: Blood
Blood (2021) 138 (Supplement 1): 3992.
https://doi.org/10.1182/blood-2021-150552
Published: 2021
Journal Articles

Preclinical Characterization of AFM26, a Novel B Cell Maturation Antigen (BCMA)-Directed Tetravalent Bispecific Antibody for High Affinity Retargeting of NK Cells Against Myeloma

Thorsten Ross, PhD, Uwe Reusch, PhD, Susanne Wingert, PhD, Torsten Haneke, PhD, Katja Klausz, PhD, Anna-Kathrin Otte, PhD, Natalie Schub, MD, Stefan Knackmuss, PhD, Thomas Müller, Kristina Ellwanger, PhD, Ivica Fucek, Ute Schniegler-Mattox, Joachim Koch, PhD, Thomas Valerius, MD, Martin Gramatzki, MD, Matthias Peipp, PhD, Michael Tesar, PhD, Erich Rajkovic, PhD MBA, Martin Treder, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1927.
https://doi.org/10.1182/blood-2018-99-118970
Published: 2018
Journal Articles

CD16A-Specific Tetravalent Bispecific Immune Cell Engagers Potently Induce Antibody-Dependent Cellular Phagocytosis (ADCP) on Macrophages

Susanne Wingert, PhD, Uwe Reusch, PhD, Armin Beez, Jens Pahl, PhD, Adelheid Cerwenka, PhD, Joachim Koch, PhD, Martin Treder, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1111.
https://doi.org/10.1182/blood-2018-99-118427
Published: 2018
Journal Articles

Cord Blood Derived Natural Killer Cells Loaded with a Tetravalent Bispecific Antibody Construct (AFM13) As Off-the-Shelf Cell Therapy for CD30+ Malignancies

Lucila Kerbauy, MD, Mecit Kaplan, MS, Pinaki P Banerjee, PhD, Francesca Lorraine Wei Inng Lim, MD, Ana Karen Nunes Cortes, MD, May Daher, Mayela Carolina Mendt, PhD, Rafet Basar, MD, Li Li, MD, Muharrem Muftuoglu, MD, Hila Shaim, MD, Mayra Shanley, PhD, Enli Liu, MD, Sonny Ang, PhD, Rong Cai, BS, Vandana Nandivada, Richard E Champlin, MD, Joachim Koch, PhD, Martin Treder, PhD, Elizabeth J. Shpall, MD, Katy Rezvani, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 341.
https://doi.org/10.1182/blood-2018-99-114954
Published: 2018
Journal Articles

AFM26 - Targeting B Cell Maturation Antigen (BCMA) for NK Cell-Mediated Immunotherapy of Multiple Myeloma

Thorsten Gantke, PhD, Uwe Reusch, PhD, Christian Kellner, PhD, Katja Klausz, PhD, Torsten Haneke, PhD, Stefan Knackmuss, PhD, Thomas Müller, Kristina Ellwanger, PhD, Ivica Fucek, Ute Schniegler-Mattox, Joachim Koch, PhD, Anne Kerber, MD, Matthias Peipp, PhD, Martin Treder, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3082.
https://doi.org/10.1182/blood.V130.Suppl_1.3082.3082
Published: 2017
Journal Articles

AFM13 Is the Most Advanced Bispecific NK-Cell Engaging Antibody in Clinical Development Substantially Enhancing NK-Cell Effector Function and Proliferation

Jens Pahl, PhD, Uwe Reusch, PhD, Thorsten Gantke, PhD, Anne Kerber, MD, Joachim Koch, PhD, Martin Treder, PhD, Adelheid Cerwenka, PhD
Journal: Blood
Blood (2016) 128 (22): 1764.
https://doi.org/10.1182/blood.V128.22.1764.1764
Published: 2016
Journal Articles

RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation

Olga N. Kuvardina, Julia Herglotz, Stephan Kolodziej, Nicole Kohrs, Stefanie Herkt, Bartosch Wojcik, Thomas Oellerich, Jasmin Corso, Kira Behrens, Ashok Kumar, Helge Hussong, Henning Urlaub, Joachim Koch, Hubert Serve, Halvard Bonig, Carol Stocking, Michael A. Rieger, Jörn Lausen
Journal: Blood
Blood (2015) 125 (23): 3570–3579.
https://doi.org/10.1182/blood-2014-11-610519
Published: 2015
Includes: Supplemental data
Journal Articles

Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity

Christian Wichmann, Yvonne Becker, Linping Chen-Wichmann, Vitali Vogel, Anna Vojtkova, Julia Herglotz, Sandra Moore, Joachim Koch, Jörn Lausen, Werner Mäntele, Holger Gohlke, Manuel Grez
Journal: Blood
Blood (2010) 116 (4): 603–613.
https://doi.org/10.1182/blood-2009-10-248047
Published: 2010
Includes: Supplemental data