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Journal Articles

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Shouguo Gao, PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3706.

https://doi.org/10.1182/blood-2019-123204

Published: 2019

Journal Articles

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Xingmin Feng, PhD, Zenghua Lin, MD, Maile K. Hollinger, BA, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Kaylind Batey, BS, Keyvan Keyvanfar, BS, Jichun Chen, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 1310.

https://doi.org/10.1182/blood-2018-99-113488

Published: 2018

Journal Articles

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

Xingmin Feng, PhD, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Zenghua Lin, MD, Maile K Hollinger, BA, Jichun Chen, PhD, Neal S. Young, MD

Blood (2017) 130 (Supplement 1): 778.

https://doi.org/10.1182/blood.V130.Suppl_1.778.778

Published: 2017

Journal Articles

T Cells Trafficking to Bone Marrow Have Different Characteristics from Those to Other Organs in an Immune-Mediated Bone Marrow Failure Mouse Model

Zenghua Lin, MD, Xingmin Feng, PhD, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Maile K Hollinger, BA, Jichun Chen, PhD, Hong Liu, MD PhD, Neal S. Young, MD

Blood (2017) 130 (Supplement 1): 2455.

https://doi.org/10.1182/blood.V130.Suppl_1.2455.2455

Published: 2017

Journal Articles

Rapamycin Is Highly Effective in a Mouse Model of Immune-Mediated Bone Marrow Failure By Mechanisms Distinct from Cyclosporine

Xingmin Feng, PhD, Zenghua Lin, MD PhD, Marie Desierto, Keyvan Keyvanfar, BS, Daniela Malide, PhD, Jichun Chen, PhD, Neal S. Young, MD

Blood (2015) 126 (23): 1202.

https://doi.org/10.1182/blood.V126.23.1202.1202

Published: 2015

Journal Articles

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Pawel Muranski, MD, Xingmin Feng, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Christopher S. Hourigan, MD PhD, John Barrett, MD, Neal S. Young, MD

Blood (2014) 124 (21): 2940.

https://doi.org/10.1182/blood.V124.21.2940.2940

Published: 2014

Journal Articles

Adipocytes and Aplastic Anemia: Peroxisome Proliferator-Activated Receptor-γ (PPAR- γ) Antagonists Attenuate Bone Marrow Failure in an Aplastic Anemia Mouse Model but Not in Radiation Marrow Destruction

Kazuya Sato, MD, PhD, Xingmin Feng, PhD, Jichun Chen, PhD, Marie J. Desierto, Keyvan Keyvanfar, Daniela Malide, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2012) 120 (21): 3483.

https://doi.org/10.1182/blood.V120.21.3483.3483

Published: 2012

Journal Articles

Hematological Abnormalities in Aged Telomerase RNA Component Deficient Mice Are Associated with Intestinal Epithelial Degeneration and Bone Marrow Stromal Dysfunction

Jichun Chen, PhD, James J. Dent, BS, Marie J. Desierto, Mark A. Bryant, DVM, Nolan Sheppard, BA, Xingmin Feng, PhD, Neal S. Young, MD

Blood (2012) 120 (21): 1244.

https://doi.org/10.1182/blood.V120.21.1244.1244

Published: 2012

Journal Articles

Androgen Treatment Mitigates Hematopoietic Cell Telomere Attrition In Vivo

Jichun Chen, PhD, Marie J. Desierto, James J. Dent, BS, Maria J. Bachman, BS, Rodrigo T. Calado, MD, PhD, Constantine A. Stratakis, MD, Neal S. Young, MD

Blood (2012) 120 (21): 516.

https://doi.org/10.1182/blood.V120.21.516.516

Published: 2012

Journal Articles

The NSG – Human CLL Xenograft Model Recapitulates the Human Lymph Node Microenvironment in Regards to B-Cell Activation and Tumor Proliferation

Xiameng Sun, BS, Sarah E. M. Herman, PhD, Matthew M. Hsieh, MD, John F. Tisdale, Jichun Chen, PhD, Georg Aue, M.D., Patricia Perez-Galan, PhD, Adrian Wiestner, MD, PhD

Blood (2011) 118 (21): 973.

https://doi.org/10.1182/blood.V118.21.973.973

Published: 2011

Journal Articles

Does a Chronic Inflammatory Process Underlie Clonal Progression In Aplastic Anemia?- In Vitro and In Vivo Evidence That Inflammation Produces Aneuploidy for Chromosomes 7 and 8 In Replicating Cells

Elaine M Sloand, MD, Kelsey Loeliger, BA, Loretta Pfannes, BA, Andrea Poon, BS, Rodrigo Calado, MD, PhD, Xingmin Feng, PhD, Hesed Padilla-Nash, Jichun Chen, PhD, Neal S. Young, MD

Blood (2010) 116 (21): 641.

https://doi.org/10.1182/blood.V116.21.641.641

Published: 2010

Journal Articles

Endoplasmic Reticulum Stress Is a Target for Therapy in Paroxysmal Nocturnal Hemoglobinuria.

Regis Peffault de Latour, MD, PhD, Valeria Visconte, PhD, Keyvan Keyvanfar, Olga Nunez, Marie Desierto, Jichun Chen, PhD, Adrian Wiestner, MD, PhD, Neal S Young, MD

Blood (2009) 114 (22): 160.

https://doi.org/10.1182/blood.V114.22.160.160

Published: 2009

Journal Articles

Reduced Hematopoietic Stem Cell Function in a Mouse Model with Conditional Pig-a Gene Deletion.

Valeria Visconte, PhD, Regis Peffault de Latour, MD PhD, Rodrigo T. Calado, MD PhD, Marie Desierto, Jichun Chen, PhD, Neal S Young, MD

Blood (2009) 114 (22): 2428.

https://doi.org/10.1182/blood.V114.22.2428.2428

Published: 2009

Journal Articles

Clonally-Restricted T-Lymphocytes in PigA Mutant Mice.

Valeria Visconte, PhD, Nalini Raghavachari, PhD, Keyvan Keyvanfar, Delong Liu, PhD, Marie Desierto, Jichun Chen, PhD, Neal S. Young, MD

Blood (2008) 112 (11): 2040.

https://doi.org/10.1182/blood.V112.11.2040.2040

Published: 2008

Journal Articles

Critical Role of the Th1 Transcription Factor T-Bet in An Animal Model of Immune-Mediated Bone Marrow Failure

Yong Tang, Jichun Chen, PhD, Neal Young

Blood (2008) 112 (11): 1037.

https://doi.org/10.1182/blood.V112.11.1037.1037

Published: 2008

Journal Articles

Hematopoiesis in Three-Dimensions: Tissue Architecture of Murine and Human Bone Marrow Visualized to a Depth of 100 Micron by Confocal Microscopy

Tomoiku Takaku, MD, PhD, Daniela Malide, MD, PhD, Ning Zhi, MD, PhD, Rodrigo Calado, MD, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Zuxi Yu, MD, PhD, Christian A. Combs, PhD, Neal S. Young, MD, PhD

Blood (2008) 112 (11): 4781.

https://doi.org/10.1182/blood.V112.11.4781.4781

Published: 2008

Journal Articles

Rabbit ATG but Not Horse ATG Promotes Expansion of Functional CD4 + CD25 high FoxP3 Regulatory T Cells In Vitro.

Xingmin Feng, PhD, Elena E. Solomou, MD, PhD, Keyvan Keyvanfar, Thomas Herndon, MD, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD, PhD

Blood (2007) 110 (11): 2312.

https://doi.org/10.1182/blood.V110.11.2312.2312

Published: 2007

Journal Articles

Enrichment of Hematopoietic Stem Cells from Normal and Trp53 Null Mice Using SLAM Receptor CD150 as a Positive Selection Marker.

Jichun Chen, PhD, Stephanie O. Omokaro, M.D., Keyvan Keyvanfar, B.S., Neal S. Young, M.D.

Blood (2007) 110 (11): 2235.

https://doi.org/10.1182/blood.V110.11.2235.2235

Published: 2007

Journal Articles

Cell Therapy in a Mouse Model of Immune-Mediated Bone Marrow Failure.

Jichun Chen, PhD, Neal S. Young, M.D.

Blood (2007) 110 (11): 1689.

https://doi.org/10.1182/blood.V110.11.1689.1689

Published: 2007

Journal Articles

Reduced Regulatory T Cell to Activated T Cell Ratio in a Mouse Model of Immune-Mediated Bone Marrow Failure and Prevention of Aplastic Anemia by Infusion of T Regulatory Cells.

Jichun Chen, PhD, Neal S. Young, M. D

Blood (2006) 108 (11): 121.

https://doi.org/10.1182/blood.V108.11.121.121

Published: 2006

NARROW

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

T Cells Trafficking to Bone Marrow Have Different Characteristics from Those to Other Organs in an Immune-Mediated Bone Marrow Failure Mouse Model

Rapamycin Is Highly Effective in a Mouse Model of Immune-Mediated Bone Marrow Failure By Mechanisms Distinct from Cyclosporine

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

Adipocytes and Aplastic Anemia: Peroxisome Proliferator-Activated Receptor-γ (PPAR- γ) Antagonists Attenuate Bone Marrow Failure in an Aplastic Anemia Mouse Model but Not in Radiation Marrow Destruction

Hematological Abnormalities in Aged Telomerase RNA Component Deficient Mice Are Associated with Intestinal Epithelial Degeneration and Bone Marrow Stromal Dysfunction

Androgen Treatment Mitigates Hematopoietic Cell Telomere Attrition In Vivo

The NSG – Human CLL Xenograft Model Recapitulates the Human Lymph Node Microenvironment in Regards to B-Cell Activation and Tumor Proliferation

Does a Chronic Inflammatory Process Underlie Clonal Progression In Aplastic Anemia?- In Vitro and In Vivo Evidence That Inflammation Produces Aneuploidy for Chromosomes 7 and 8 In Replicating Cells

Endoplasmic Reticulum Stress Is a Target for Therapy in Paroxysmal Nocturnal Hemoglobinuria.

Reduced Hematopoietic Stem Cell Function in a Mouse Model with Conditional Pig-a Gene Deletion.

Clonally-Restricted T-Lymphocytes in PigA Mutant Mice.

Critical Role of the Th1 Transcription Factor T-Bet in An Animal Model of Immune-Mediated Bone Marrow Failure

Hematopoiesis in Three-Dimensions: Tissue Architecture of Murine and Human Bone Marrow Visualized to a Depth of 100 Micron by Confocal Microscopy

Rabbit ATG but Not Horse ATG Promotes Expansion of Functional CD4 + CD25 high FoxP3 Regulatory T Cells In Vitro.

Enrichment of Hematopoietic Stem Cells from Normal and Trp53 Null Mice Using SLAM Receptor CD150 as a Positive Selection Marker.

Cell Therapy in a Mouse Model of Immune-Mediated Bone Marrow Failure.

Reduced Regulatory T Cell to Activated T Cell Ratio in a Mouse Model of Immune-Mediated Bone Marrow Failure and Prevention of Aplastic Anemia by Infusion of T Regulatory Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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