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Journal Articles

Cannabidiol attenuates hyperalgesia in a mouse model of sickle cell disease

Hemanth M. Cherukury, Donovan A. Argueta, Natalie Garcia, Raghda Fouda, Stacy Kiven, Jianxun Lei, Varun Sagi, Graham J. Velasco, Bryant Avalos, Nicholas V. DiPatrizio, Kalpna Gupta
Journal: Blood
Blood (2023) 141 (2): 203–208.
https://doi.org/10.1182/blood.2022016382
Published: 2023
Includes: Supplemental data
Journal Articles

Downregulation of Sprr1a Contributes to the Pathobiology of Sickle Cell Disease

Donovan A Argueta, BSc, Anupam Aich, PhD, Jianxun Lei, PhD, Sergei Nekhai, PhD, Tatiana Ammosova, PhD, Xionghao Lin, PhD, Anindya Bagchi, PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 75.
https://doi.org/10.1182/blood-2019-129004
Published: 2019
Journal Articles

Cannabidiol Reduces Acute and Chronic Hyperalgesia in Humanized Sickle Mice

Varun Sagi, BS, Jianxun Lei, PhD, Stacy B Kiven, BS, Huy Tran, BS, Kalpna Gupta, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 77.
https://doi.org/10.1182/blood-2019-129706
Published: 2019
Journal Articles

Calpain-1 Contributes to Pain and Organ Damage in Sickle Cell Disease

Stacy B Kiven, BS, Jianxun Lei, PhD, Varun Sagi, BS, Huy Tran, BS, Ying Wang, PhD, Piyusha P Pagare, PhD, Jennifer O Nwankwo, PhD, Nils Lambrecht, MD PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 76.
https://doi.org/10.1182/blood-2019-127761
Published: 2019
Journal Articles

Mast Cells Contribute to Brain Microvascular Permeability in Sickle Cell Disease

Aditya M Mittal, Huy Tran, BSMedTech, Varun Sagi, BS, Aithanh Nguyen, Kathryn Luk, Julia Nguyen, BS, Jianxun Lei, PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 269.
https://doi.org/10.1182/blood-2018-99-117246
Published: 2018
Journal Articles

Targeting Central Mechanisms of Pain to Improve Acupuncture Analgesia in a Humanized Mouse Model of Sickle Cell Disease

Ying Wang, MD PhD, Jianxun Lei, PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1064.
https://doi.org/10.1182/blood-2018-99-115577
Published: 2018
Journal Articles

Regulation of Elastase By SerpinA3N Contributes to Pain in Sickle Cell Disease

Anupam Aich, PhD, Jinny Paul, PhD, Jianxun Lei, PhD, Ying Wang, MD PhD, Anindya Bagchi, PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2016) 128 (22): 858.
https://doi.org/10.1182/blood.V128.22.858.858
Published: 2016
Journal Articles

Pharmacological Inhibition of TLR4 Reduces Mast Cell Activation, Neuroinflammation and Hyperalgesia in Sickle Mice

Jianxun Lei, PhD, Ying Wang, MD PhD, Jinny Paul, PhD, Susan Thompson, B.S., Ritu Jha, M.Sc, Kalpna Gupta, PhD
Journal: Blood
Blood (2015) 126 (23): 278.
https://doi.org/10.1182/blood.V126.23.278.278
Published: 2015
Journal Articles

Acupuncture Led Attenuation of Inflammatory and Nociceptive Peripheral and Central Microenvironment in Sickle Mice

Ying Wang, MD PhD, Jianxun Lei, PhD, Yann Y Lamarre, PhD, Ritu Jha, M.sc, Fei Peng, M.sc, Sarah Lam, Ellis Raduenz, Deniz Ercan-Fang, Kalpna Gupta, PhD
Journal: Blood
Blood (2015) 126 (23): 2169.
https://doi.org/10.1182/blood.V126.23.2169.2169
Published: 2015
Journal Articles

Hemin-Induced Mast Cell-Extracellular Traps Impart Resistance to Therapy in a Sickle Microenvironment

Huy Tran, BS, Ritu Jha, M.sc, Julia Nguyen, BS, Sarita Jarrett, High School, Jonathan Rodriguez, Undergraduate, Aditya Mittal, High School, Jianxun Lei, PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2015) 126 (23): 3385.
https://doi.org/10.1182/blood.V126.23.3385.3385
Published: 2015
Journal Articles

Heme Induced Spinal Microglial Cell Activation By TLR4 and Endoplasmic Reticulum Stress in Sickle Mice

Jinny Paul, PhD, Jianxun Lei, PhD, Ritu Jha, MS, Julia Nguyen, BS, Donald A Simone, PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2014) 124 (21): 452.
https://doi.org/10.1182/blood.V124.21.452.452
Published: 2014