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Jian Jin, PhD
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Journal Articles

Akt Inhibition Differently Controls PRC2 Components and Synergizes with Dual EZH2/1 Inhibitor in the Treatment of Multiple Myeloma

Mohamed Rizk, BSc, MSc, Ola Rizq, MD PhD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Shuhei Koide, PhD, Atsunori Saraya, Yusuke Isshiki, MD PhD, Tetsuhiro Chiba, MD PhD, Satoshi Yamazaki, PhD, Anqi Ma, PhD, Jian Jin, PhD, Atsushi Iwama, MD PhD, Naoya Mimura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4400.
https://doi.org/10.1182/blood-2019-122157
Published: 2019
Journal Articles

Inhibition of PRMT1 Mediated FLT3 Arginine Methylation As a Potent Therapeutic Strategy for MLL-r ALL

Yinghui Zhu, PhD, Xin He, PhD, Haojie Dong, PhD, Jie Sun, PhD, Hanying Wang, PhD, Lei Zhang, PhD, Yunan Miao, PhD, Jian Jin, PhD, Yudao Shen, PhD, Jianjun Chen, PhD, Markus Muschen, MD, Chun-Wei Chen, PhD, Marina Y. Konopleva, MD PhD, Weili Sun, MD PhD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD PhD, Guido Marcucci, Ling Li, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 892.
https://doi.org/10.1182/blood-2018-99-115139
Published: 2018
Journal Articles

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Xin He, PhD, Yinghui Zhu, PhD, Haojie Dong, PhD, Sierra Min Li, Zonghui Ding, PhD, Jie Sun, PhD, Juan Du, MDPhD, Hanying Wang, PhD, Lianjun Zhang, PhD, Yudao Shen, PhD, Hairui Su, BS, PhD, Samer K. Khaled, MD, Dandan Zhao, MD, Lei Zhang, PhD, Robert Hickey, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Xinyang Zhao, PhD, Jian Jin, PhD, Nadia Carlesso, MD PhD, Jianjun Chen, PhD, Yang Xu, MD, Guido Marcucci, Ling Li, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 760.
https://doi.org/10.1182/blood-2018-99-112766
Published: 2018
Journal Articles

Targeting PRMT1 As a Novel Curative Therapy for Acute Myeloid Leukemia

Hairui Su, BS, PhD, Shuiling Jin, PhD, Yudao Shen, Matthew A. Kutny, MD, Jian Jin, PhD, Minkui Luo, Xinyang Zhao, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2650.
https://doi.org/10.1182/blood.V130.Suppl_1.2650.2650
Published: 2017
Journal Articles

Identification of EHMT2 As a New Target in T-Cell Acute Lymphoblastic Leukemia

Samuel Kitara, Angela Su, Claudio Deluca, Franco Aversa, MD, Birgit Knoechel, MDPhD, Jian Jin, PhD, Kimberly Stegmaier, MD, Giovanni Roti, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2548.
https://doi.org/10.1182/blood.V130.Suppl_1.2548.2548
Published: 2017
Journal Articles

Molecular Mechanism behind the Synergistic Activity of Proteasome Inhibition and PRC2 Inhibition in the Treatment of Multiple Myeloma

Ola Rizq, MD, Naoya Mimura, MD PhD, Motohiko Oshima, PhD, Atsunori Saraya, Shuhei Koide, PhD, Yuko Kato, PhD, Kazumasa Aoyama, PhD, Yaeko Nakajima-Takagi, PhD, Changshan Wang, PhD, Anqi Ma, Jian Jin, PhD, Tohru Iseki, MD PhD, Chiaki Nakaseko, MD, PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2016) 128 (22): 312.
https://doi.org/10.1182/blood.V128.22.312.312
Published: 2016
Journal Articles

SET8 Is a Potential Therapeutic Target in MM

Herviou Laurie, Fanny Izard, Elke De Bruyne, PhD, Eva Desmedt, Anqi Ma, PhD, Jian Jin, PhD, Karin Vanderkerken, PhD, Eric Julien, Jerome Moreaux, PhD
Journal: Blood
Blood (2016) 128 (22): 4435.
https://doi.org/10.1182/blood.V128.22.4435.4435
Published: 2016
Journal Articles

EZH2 Inhibition and the Combination with Proteasome Inhibition Are Novel Potential Strategies for the Treatment of Multiple Myeloma

Ola Rizq, Naoya Mimura, MD PhD, Shuhei Koide, Anqi Ma, PhD, Jian Jin, PhD, Tohru Iseki, MD PhD, Chiaki Nakaseko, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2094.
https://doi.org/10.1182/blood.V124.21.2094.2094
Published: 2014