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Jesús-María Hernández-Rivas, MD PhD
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Journal Articles

Phase 3 Study of Lenalidomide (LEN) Vs Placebo in Non-Transfusion Dependent (TD) Low Risk Del(5q) MDS Patients - Interim Analysis of the European Sintra-REV Trial

Félix López Cadenas, MD, Eva Lumbreras, Blanca Xicoy, MD, Joaquín Sánchez, MD, Rosa Coll, MD, Bohrane Slama, MD, Jose Angel Hernandez-Rivas, MD PhD, Sylvain Thepot, MD, Teresa Bernal, MD PhD, Beatriz Arrizabalaga, MD PhD, Agnès Guerci-Bresler, MD PhD, Guillermo F Sanz, MD PhD, Joan Bargay, MD, Maria Luz Amigo, MD, Raquel de Paz, MD, Benet Nomdedeu, MD, Aristoteles Giagounidis, Uwe Platzbecker, Stefan Wickenhauser, Katharina S. Götze, Ali Arar, Jesus María Hernández Rivas, MD PhD, Pierre Fenaux, MD PhD, Consuelo Del Cañizo, MDPhD, Maria Diez-Campelo, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-140339
Published: 2020
Journal Articles

Clinical and Biological Impact of TP53 Alterations in Del(11q) Chronic Lymphocytic Leukemia

Claudia Pérez Carretero, MSc, BSc, Miguel Quijada Álamo, MSc, Maria Hernandez-Sanchez, PhD, Ana E. Rodriguez, PhD, Ana B Herrero, PhD, Jesus M Hernández-Sánchez, PhD, Marta Martín Izquierdo, MSc, Teresa González, PhD, Sandra Santos-Mínguez, Cristina Miguel-García, Araceli Rubio-Martínez, Alfonso García de Coca, MD PhD, Julio Dávila, Jose-Angel Hernandez, MD PhD, Rocio Benito, PhD, José Luis Ordóñez, PhD, Jesus Maria Hernández-Rivas, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-141015
Published: 2020
Journal Articles

A New Risk Stratification Model (R2-ISS) in Newly Diagnosed Multiple Myeloma: Analysis of Mature Data from 7077 Patients Collected By European Myeloma Network within Harmony Big Data Platform

Mattia D'Agostino, MD, Juan-José Lahuerta, MD PhD, Ruth Wester, MD, Anders Waage, MD PhD, Uta Bertsch, Elena Zamagni, Maria-Victoria Mateos, MD PhD, Alessandra Larocca, Daniele Dall'Olio, Niels W. C. J. van de Donk, David Cairns, MSc, PhD, Serena Rocchi, Hans Salwender, MD, Joan Blade Creixenti, Bronno van der Holt, PhD, Castellani Gastone, Giovannino Ciccone, Andrea Capra, Jan Dürig, MD, Sara Bringhen, MD, Sonja Zweegman, MDPhD, Michele Cavo, Hartmut Goldschmidt, MD, Gordon Cook, MB ChB, PhD, Jesus Maria Hernández-Rivas, MD PhD, Jesus F. San-Miguel, MD PhD, Mario Boccadoro, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–37.
https://doi.org/10.1182/blood-2020-137021
Published: 2020
Journal Articles

Biological Impact of Monoallelic and Biallelic BIRC3 Loss in Del(11q) Chronic Lymphocytic Leukemia Progression

Miguel Quijada Álamo, MSc, Maria Hernandez-Sanchez, PhD, Ana E. Rodriguez, PhD, Claudia Pérez Carretero, MSc, BSc, Marta Martín Izquierdo, MSc, Verónica Alonso Pérez, PhD, Ignacio García-Tuñón, PhD, Jose Maria Bastida, MDPhD, Maria Jesus Vidal, MD, Josefina Galende DEL Canto, MD, Carlos Aguilar, MD, José Antonio Queizán, MD, Isabel González-Gascón Y Marín, MD PhD, Jose-Angel Hernandez, MD PhD, Rocio Benito, PhD, José Luis Ordóñez, PhD, Jesus Maria Hernández-Rivas, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4.
https://doi.org/10.1182/blood-2020-142658
Published: 2020
Journal Articles

Validation and Improvement Opportunities of the Revised International Staging System for Multiple Myeloma: An Analysis on Mature Data from European Clinical Trials within the Harmony Big Data Platform

Mattia D'Agostino, MD, Anders Waage, MD PhD, Juan-José Lahuerta, MD PhD, Uta Bertsch, Elena Zamagni, MD, Lars Bullinger, Alessandra Larocca, Maria-Victoria Mateos, Niels W. C. J. Van De Donk, Hans Jürgen Salwender, MD, Joan Bladé, MD, Bronno van der Holt, PhD, Paola Tacchetti, Giovannino Ciccone, Sonja Zweegman, Hartmut Goldschmidt, Michele Cavo, Jesús San-Miguel, Pieter Sonneveld, Mario Boccadoro, Jesús María Hernández-Rivas, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1773.
https://doi.org/10.1182/blood-2019-124321
Published: 2019
Journal Articles

Ponatinib and Chemotherapy in Young Adults with De Novo Philadelphia Chromosome-Positive Acute Lymphoblstic Leukemia. Preliminary Results of Ponalfil Clinical Trial

Josep-Maria Ribera, MD PhD, Olga García, Pilar Martinez, MD, Pau Montesinos Fernandez, MD PhD, Blanca Boluda, Jordi Esteve, Daniel Esteban, María José Moreno, MD, Natalia Alonso, José González-Campos, MD, Arancha Bermúdez, Susana Vives, MD, Mar Tormo, MD PhD, Jesús María Hernández-Rivas, MD PhD, Joaquin Martinez-Lopez, MD PhD, Ramón García-Sanz, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3874.
https://doi.org/10.1182/blood-2019-125558
Published: 2019
Journal Articles

Rituximab and Specific Therapy for Patients with Burkitt's Leukemia and Lymphoma. Results of the BURKIMAB14 Trial from the Spanish Pethema and Geltamo Groups in 80 Patients

Josep-Maria Ribera, MD PhD, Olga García, Marta Cervera, MD, Carlos Rguez, Maialen Sirvent, Ferran Vall-Llovera, MD, Pau Abrisqueta, MD PhD, Josefina Serrano, Buenaventura Buendía, Pau Montesinos Fernandez, MD PhD, Susana Vives, MD, Juan Miguel Bergua Burgues, Mariana Beatriz Bastos-Oreiro, PhD MD, Evelyn Acuña, María José Moreno, MD, Irene García-Cadenas, Maria Jose Terol, Jesús María Hernández-Rivas, MD PhD, Antonio Garcia-Guiñon, MD, Pilar Herrera Puente, Santiago Mercadal, MD, Iulia Ivan, Antonia Cladera, Eva Gimeno Vázquez, Anna Torrent, Alfons Serrano-Maestro, MD, Cristina Barrenetxea, Daniel García, MD, Reyes Arranz, Ana Sebrango, Natalia Alonso, Daniel Martínez-Carballeira, MD, Juan-Manuel Sancho, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2584.
https://doi.org/10.1182/blood-2019-125683
Published: 2019
Journal Articles

A New Gene Expression Profile Signature CRLF2 Overexpression Based Identifies Novel Adult "Triple Negative" Acute Lymphoblastic Leukemia Subgroups

Anna Ferrari, PhD, Silvia Vitali, PhD, Valentina Robustelli, PhD, Andrea Ghelli Luserna Di Rora, Simona Righi, Giovanni Pasquini, Cristina Papayannidis, Giovanni Marconi, Giulia Ferrari, Maria Chiara Fontana, MSc, Enrica Imbrogno, Eugenio Fonzi, PhD, Antonella Padella, Giorgia Simonetti, PhD, Alessandra Santoro, PhD, Jesús-María Hernández-Rivas, MD PhD, Michela Tebaldi, Samanta Salvi, Carmen Baldazzi, Maria Chiara Abbenante, Nicoletta Testoni, BSc, Massimiliano Bonafè, Castellani Gastone, Elena Sabattini, Michele Cavo, MD, Daniel Remondini, Giovanni Martinelli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5284.
https://doi.org/10.1182/blood-2018-99-118062
Published: 2018
Journal Articles

Ten New Cases of Hermansky-Pudlak Syndrome in the Iberian Peninsula: Identification of Novel Genetic Variants in HPS3, HPS4, HPS6 and DTNBP1 Associated with Significant Clinical Complications

Jose Maria Bastida, MDPhD, Sara Morais, MD, Veronica Palma-Barqueros, Rocio Benito, PhD, Nuria Bermejo, MD, Mutlu Karkucak, MD, Maria Trapero-Marugan, MD, Natalia Bohdan, Monica Pereira, MD, Ana Marín-Quílez, Jorge Oliveira, MD, Yusuf Yucel, MD, Rosario Santos, MD, Jose Padilla, PhD, Kamila Janusz, Ana Hortal, MD, Vicente Vicente Garcia, MD PhD, Jesús-María Hernández-Rivas, MD PhD, Maria L Lozano, MD PhD, Jose Ramon González-Porras, MDPhD, Margarida Lima, MD, Jose Rivera, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1147.
https://doi.org/10.1182/blood-2018-99-112968
Published: 2018
Journal Articles

Prospective National-Base Multicenter Study to Standardize the Follow-up of Type 1Gaucher Disease Patients Treated with Eliglustat Under Standard of Care Practice. Trazelga Project

Marcio M Andrade-Campos, PhD, Jorge J Cebolla, MSc, Laura Lopez de Frutos, PhD, Pilar Irun, PhD, Soledad Noya, MD, Santiago Nieto, MD, Lucia Villalon, PhD, Ana I Arribas, MD, Abelardo Barez, PhD, Javier Garcia-Frade, PD, Maria Lourdes Hermosin, MD, Jesús-María Hernández-Rivas, MD PhD, Daiana Ibarretxe, MD, Maria L Lozano, MD PhD, Teresa Molero, PhD, Maria Angeles Perez-Saenz, MDPhD, Jesus Villarrubia, PhD, Pilar Giraldo, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4942.
https://doi.org/10.1182/blood-2018-99-115534
Published: 2018
Journal Articles

Phase 3 Study of Lenalidomide (LEN) Vs Placebo in Non-Transfusion Dependent (TD) Low Risk Del(5q) MDS Patients with Del(5q) — Preliminary Blinded Analysis of the European Sintra-REV Trial

Félix López Cadenas, MD, Eva Lumbreras, Blanca Xicoy, Joaquin Sanchez-Garcia, MD PhD, Pierre Fenaux, MD PhD, Rosa Coll, Borhane Slama, MD, Jose Angel Hernandez-Rivas, MD, Sylvain Thepot, MD, Teresa Bernal, MD, Beatriz Arrizabalaga, MD PhD, Agnès Guerci, Guillermo Sanz, Joan Bargay, MD PhD, Maria Luz Amigo, Raquel de Paz, Aristoteles Giagounidis, Uwe Platzbecker, Benet Nomdedeu, Eric Jourdan, MD, Katharina S. Götze, MD, Ali Arar, Jesús María Hernández-Rivas, MD PhD, Consuelo Del Cañizo, MDPhD, María Díez-Campelo
Journal: Blood
Blood (2018) 132 (Supplement 1): 468.
https://doi.org/10.1182/blood-2018-99-119430
Published: 2018
Journal Articles

CRISPR/Cas9-Generated Models Uncover Therapeutic Vulnerabilities of Del(11q) Chronic Lymphocytic Leukemia Cells to Dual BCR and PARP Inhibition

Miguel Quijada Álamo, BSc, MSc, María Hernández-Sánchez, PhD, José Luis Ordóñez, PhD, Verónica Alonso Pérez, PhD, Ana E. Rodriguez, PhD, Ignacio García-Tuñón, PhD, Ana B Herrero, PhD, Laura San-Segundo, Michaela Gruber, MD PhD, Juan Luis García, PhD, Rocio Benito, PhD, Catherine J. Wu, MD, Jesús-María Hernández-Rivas, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 948.
https://doi.org/10.1182/blood-2018-99-116080
Published: 2018
Journal Articles

rs2431697, a Polymorphism of Mir-146a, Is a Precozing Marker of Progression to Secondary Myelofibrosis: New Epigenetic Regulation of Jak/Stat3 Signaling

Francisca Ferrer Marin, MD PhD, Ana Belen F Arroyo, PhD, Beatriz Bellosillo, PhD, Lurdes Zamora, PhD, Ana Kerguelen Fuentes, MD PhD, Patricia Vélez, MD, Elisa Luño, MD PhD, Juan Carlos Hernandez Boluda, MD PhD, Rosa Ayala, MD PhD, Dolly Viviana Fiallo, MD, Jose Valentín García Gutiérrez, MD PhD, Beatriz Arrizabalaga, MD PhD, María Teresa Gómez-Casares, MD PhD, Concepcion Boque, MD PhD, Carmen Garcia-Hernandez, MD, Jesús María Hernández-Rivas, MD PhD, Carles Besses, MD PhD, Vicente Vicente, MD PhD, Alberto Alvarez-Larrán, MD PhD, Raul Teruel Montoya, PhD, Rocio González-Conejero, PhD, Constantino Martínez, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3072.
https://doi.org/10.1182/blood-2018-99-119221
Published: 2018
Journal Articles

Characteristics and Outcome of Early T Cell Precursor ALL (ETP-ALL) Patients Treated with High-Risk Spanish Pethema Protocols

Eulalia Genesca, PhD, Mireia Morgades, M.Prob.S, Pau Montesinos, MD PhD, Pere Barba, MD, Cristina Gil, MD PhD, Ramon Guàrdia, MD, Maria Jose Moreno, MD, Daniel Martínez-Carballeira, MD, Irene García-Cadenas, Susana Vives, MD, Jordi Ribera, José González-Campos, MD, Marina Diaz-Beyá, MD, Santiago Mercadal, MD, Maria Teresa Artola, MD, Antonia Cladera, MD, Mar Tormo, MD PhD, Arancha Bermudez, MD, Ferran Vall-Llovera, MD, Pilar Martinez, MD, María-Luz Amigo, MD, Juan-Miguel Bergua, MD, María Calbacho, MD, Jesús-María Hernández-Rivas, MD PhD, Silvia Monsalvo, Andrés Novo, MD, Marta Cervera, MD, Antonio Garcia-Guiñon, MD, Jordi Junca, MD, Juana Ciudad, PhD, Alberto Orfao, MD PhD, Josep-Maria Ribera, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1553.
https://doi.org/10.1182/blood-2018-99-114559
Published: 2018
Journal Articles

Genomic Instability and a Preferential Involvement of Ras Pathway in the Myelodysplastic Syndromes Evolution to Secondary Acute Myeloid Leukemia

Marta Martín Izquierdo, MSc, María Abáigar, PhD, Jesus M Hernández-Sánchez, MSc, Félix López Cadenas, MD, Fernando Ramos, Eva Lumbreras, Andrés Madinaveitia-Ochoa, Marta Megido, Jorge Labrador, Javier Sánchez del Real, Carmen Olivier, Julio Dávila, Carlos Aguilar, Juan Nicolás Rodríguez, Guillermo Martín-Nuñez, Sandra Santos-Mínguez, Rocio Benito, PhD, Consuelo Del Cañizo, MD PhD, María Díez-Campelo, Jesús María Hernández-Rivas, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3082.
https://doi.org/10.1182/blood-2018-99-118224
Published: 2018
Journal Articles

Chronic Lymphocytic Leukemia Patients with IGH Rearrangements Are Characterized By a Distinct Genetic Landscape with Prognostic Implications

Claudia Pérez Carretero, MSc, BSc, Maria Hernandez-Sanchez, Teresa Gonzalez, Miguel Quijada Álamo, BSc, MSc, Marta Martín Izquierdo, MSc, Jesus M Hernández-Sánchez, MSc, Sandra Santos-Mínguez, María-Jesús Vidal, Alfonso García de Coca, MD PhD, Carlos Aguilar, Manuel Vargas-Pabón, Sara Alonso, MD, Magdalena Sierra, Araceli Rubio-Martínez, Julio Dávila, José R Díaz-Valdés, Jose Antonio Queizan, Jose Angel Hernandez-Rivas, MD, Maria-Victoria Mateos, MD PhD, Rocio Benito, PhD, Ana E. Rodriguez, PhD, Jesús-María Hernández-Rivas, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3129.
https://doi.org/10.1182/blood-2018-99-115959
Published: 2018
Journal Articles

Preexisting Mutations in Hematopoietic Stem Cells in Patients with Therapy-Related Myeloid Neoplasms

Mariam Ibañez, Maria López-Pavía, Esperanza Such, Blanca Navarro, Alexander Neef, PhD, Javier Marco, Mireia Boluda-Navarro, Marta Llop, Claudia Sargas, Beatricce De Matteo, Alessandro Liquori, PhD, Elisa Gonzalez, Andres Jerez, David Valcárcel, Julia Montoro, Maria Díez-Campelo, Jesús-María Hernández-Rivas, MD PhD, Jesus M Hernández-Sánchez, Teresa Bernal Del Castillo, MD PhD, Alejandra Sanjuan, PhD, Pau Montesinos, MD PhD, Eva Barragán, Miguel A. Sanz, MD, José Cervera, MD PhD, Guillermo Sanz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3956.
https://doi.org/10.1182/blood.V130.Suppl_1.3956.3956
Published: 2017
Journal Articles

Results of the Full Pediatric, Minimal Residual Disease (MRD)-Oriented Trial LAL-RI/2008 for Adolescents and Young Adults (AYA) with Standard Risk (SR), Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia (ALL)

Josep-Maria Ribera, MD, Mireia Morgades, M.Prob.S, Pau Montesinos, MD PhD, Daniel Martínez-Carballeira, MD, Cristina Gil, MD, Pere Barba, MD, Mar Tormo, MD PhD, Raimundo García-Boyero, MD, Ramon Guàrdia, MD, María Pedreño, MD, Santiago Mercadal, MD, Andrés Novo, MD, Jesús-María Hernández-Rivas, MD PhD, Juan Bergua, MD, José González-Campos, MD, María-Luz Amigo, MD, Marta Cervera, MD, Pilar Martínez-Sánchez, MD, Rodrigo Martino, MD PhD, María Calbacho, MD, Antoni Garcia-Guiñon, MD, Susana Vives, MD, Evarist Feliu, MD PhD, Alberto Orfao, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1273.
https://doi.org/10.1182/blood.V130.Suppl_1.1273.1273
Published: 2017
Journal Articles

Is the Outcome of Patients with High Risk T-Cell Acute Lymphoblastic Leukemia Improving in the Era of Pediatric—Inspired Protocols? a Comparison of 2 Consecutive Pethema Trials

Pere Barba, MD, Mireia Morgades, M.Prob.S, Pau Montesinos, MD PhD, Cristina Gil, MD, Maria Laura Fox, Juana Ciudad, maria Jose Moreno, José González-Campos, MD, Eulalia Genesca, Daniel Martínez-Carballeira, MD, Rodrigo Martino, MD PhD, Susana Vives, MD, Ramon Guàrdia, MD, Santiago Mercadal, MD, Maria Teresa Artola, Antonia Cladera, Mar Tormo, MD PhD, Jordi Esteve, MD, Juan Bergua, MD, Ferran Vall-Llovera, Jordi Ribera, Pilar Martínez-Sánchez, MD, María-Luz Amigo, MD, Arancha Bermudez, María Calbacho, MD, Jesús-María Hernández-Rivas, MD PhD, Evarist Feliu, MD PhD, Josep-Maria Ribera, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1323.
https://doi.org/10.1182/blood.V130.Suppl_1.1323.1323
Published: 2017
Journal Articles

Frequency and Prognostic Significance of the Presence of Additional Cytogenetic Abnormalitions (ACA) to the Philadelphia (Ph) Chromosome in Young Adults with ACUTE Lymphoblastic Leukemia (ALL) Treated with the ALL Ph08 Trial from the Pethema Group

Cristina Motlló, MD, Josep-Maria Ribera, MD PhD, Mireia Morgades, MProbS, Isabel Granada, Pau Montesinos, MD PhD, Santiago Mercadal, MD, José González-Campos, MD, Maria-José Moreno, MD, Pere Barba, MD PhD, Marta Cervera, MD, Manuel Barrios, MD, Andrés Novo, MD, Teresa Bernal, MD PhD, Jesus María Hernandez-Rivas, MD PhD, Eugenia Abella, MD PhD, Maria Luz Amigo, MD, Mar Tormo, MD, Rodrigo Martino, MD PhD, Esperanza Lavilla, MD, Juan Bergua, MD, Alfons Serrano, MD, Daniel García-Belmonte, MD, Ramon Guàrdia, MD PhD, Javier Grau, Evarist Feliu, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1602.
https://doi.org/10.1182/blood.V128.22.1602.1602
Published: 2016