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Jeffrey J. Molldrem, M.D.
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Journal Articles

B Cell With Regulatory Function Are Enriched Within Transitional and IgM Memory B Cell Subsets In Healthy Donors But Are Reduced and Functionally Impaired In Patients With Chronic Graft-Versus-Host Disease

Anushruti Sarvaria, Ahmad Khoder, MD, Abdullah Alsuliman, PhD, Claude Chew, Takuya Sekine, Nichola Cooper, MD, Hugues de Lavallade, MD, Muharrem Muftuoglu, Eric Yvon, PhD, Amir Hamdi, MD, Amin Alousi, MD, Lisa S St. John, PhD, David Marin, MD, Kate Stringaris, MD, MRCP, FRCPath, Enli Liu, MD, MS, Jeffrey J. Molldrem, M.D., Nina Shah, MD, Simrit Parmar, MD, Ian K. McNiece, PhD, Richard E Champlin, MD, Elizabeth J Shpall, MD, Katayoun Rezvani, M.D., PhD
Journal: Blood
Blood (2013) 122 (21): 4478.
https://doi.org/10.1182/blood.V122.21.4478.4478
Published: 2013
Journal Articles

RNA-Seq Expression Profiling of AML Stem Cells Reveals Differential Expression of Lineage Differentiation Markers and Novel Splice Variants.

Benjamin G Vincent, MD, Darshan Singh, MS, Michael Wu, PhD, Sally A. Hunsucker, PhD, Gheath Alatrash, DO, PhD, Kathryn Ruisaard, MS, Pariya Sukhumalchandra, BS, Karen Clise-Dwyer, PhD, Jonathan S Serody, MD, Jan F Prins, PhD, Jeffrey J. Molldrem, M.D., Paul M. Armistead, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2502.
https://doi.org/10.1182/blood.V120.21.2502.2502
Published: 2012
Journal Articles

Breaking Immune Tolerance to Granule Proteases with Full-Length Antigen Vaccine in Humanized Transgenic Mice Reveals Alternative Antigen Processing and Immunodominance Heirarchy Applicable to Clinical Immunotherapy.

J. Diamond Don, Ph.D, Wendi Zhou, Ph.D, Tumul Srivastava, Ph.D, Ravindra Rawal, Ph.D, Katharine Hagan, Helen A Andersson, Ph.D, J. N. Cooper Laurence, M.D., Jeffrey J. Molldrem, M.D., Simon F. Lacey, PhD, BSc
Journal: Blood
Blood (2009) 114 (22): 2054.
https://doi.org/10.1182/blood.V114.22.2054.2054
Published: 2009
Journal Articles

Anti-PR1/HLA-A2 Antibody (8F4, A TCR-Mimic) Mediates Specific Lysis of AML Stem Cells but Not Normal Hematopoietic Stem Cells.

Anna Sergeeva, Ph.D., Gheath Alatrash, D.O., Ph.D., Karen Clise-Dwyer, Ph.D., Kathryn E Quintanilla, Sijie Lu, Ph.D., Qing Ma, Ph.D., Dan Li, Ph.D., Yang Wang, M. James You, M.D., Ph.D., Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2009) 114 (22): 15.
https://doi.org/10.1182/blood.V114.22.15.15
Published: 2009
Journal Articles

Cytotoxic T Lymphocytes (CTL) Specific for CMV, Adenovirus, and EBV Can Be Generated From Naive T Cells for Adoptive Immunotherapy.

Patrick Hanley, Barbara Savoldo, MD, PhD, Conrad Russell Young Cruz, MD, Ann M. Leen, PhD, Jeffrey J. Molldrem, M.D., Hao Liu, Adrian P. Gee, PhD, Helen E. Heslop, MD, Gianpietro Dotti, MD, John Rodgers, PhD, Cliona M Rooney, PhD, Malcolm K. Brenner, MB, PhD, FRCP, FRCPath, Elizabeth J. Shpall, MD, Catherine M. Bollard, MD, FRACP, FRCPA
Journal: Blood
Blood (2009) 114 (22): 504.
https://doi.org/10.1182/blood.V114.22.504.504
Published: 2009
Journal Articles

T-Cell Immunity to Two HLA-A2-Restricted Self-Determinants of Cyclin E May Contribute to Remission After Stem Cell Transplantation.

Hong He, M.D., Ph.D., Ken Ishiyama, M.D., Ph.D., Gheath Alatrash, D.O., Ph.D., Yukio Kondo, M.D., Ph.D., Sijie Lu, Ph.D., Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2009) 114 (22): 686.
https://doi.org/10.1182/blood.V114.22.686.686
Published: 2009
Journal Articles

LFA-1 Regulates CD8 + T Cell Activation and Immune Signal Network.

Dan Li, Ph.D., Hua Li, Shoudan Liang, Ph.D., Jeffrey J. Molldrem, M.D., Qing Ma, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 1641.
https://doi.org/10.1182/blood.V114.22.1641.1641
Published: 2009
Journal Articles

Randomized Phase II Study of Proteinase 3-Derived PR1 Peptide Vaccine and GM-CSF with or without PEG-Interferon ALFA-2B to Eradicate Minimal Residual Disease in Chronic Myeloid Leukemia

Alfonso QuintásCardama, Hagop M. Kantarjian, Rosa Rios, Eric D. Wieder, Ph.D., Jeffrey J. Molldrem, M.D., Jorge Cortes
Journal: Blood
Blood (2008) 112 (11): 3219.
https://doi.org/10.1182/blood.V112.11.3219.3219
Published: 2008
Journal Articles

Regulatory and Naïve T Cells in Unmanipulated Donor Grafts Are Not Associated with Acute Graft Vs Host Disease in Matched Sibling Transplants for AML

Jahan S. Khalili, Rima M Saliba, Ph.D., Lisa St. John, Ph.D., Amin Alousi, M.D., Eric D. Wieder, Ph.D., Marcos De Lima, M.D., Richard Champlin, M.D., Jeffrey J. Molldrem, M.D., E. J. Shpall, M.D., John McMannis, Ph.D., Krishna V. Komanduri, M.D.
Journal: Blood
Blood (2008) 112 (11): 719.
https://doi.org/10.1182/blood.V112.11.719.719
Published: 2008
Journal Articles

Demonstration of a Direct Immunomodulatory Role for Vitamin D in Human T Cells Using Flow Cytometry

Richard W. Joseph, Jr., MD, Tae Kon Kim, Lisa St. John, Jahan Khalili, Uday R Popat, Richard E Champlin, MD, Jeffrey J. Molldrem, M.D., Eric Wieder, Ph.D, Krishna Komanduri, MD
Journal: Blood
Blood (2008) 112 (11): 2577.
https://doi.org/10.1182/blood.V112.11.2577.2577
Published: 2008
Journal Articles

Aberrant Subcellular Localization of Azurophil Granule Proteins in Myeloid Leukemia Favors Peptide Antigen Presentation on MHC-I and Susceptibility to Killing by Cytotoxic T Lymphocytes.

Gheath Alatrash, DO, PhD, Yoko Ono, Ph.D., Sijie Lu, Ph.D., Anna Sergeeva, Ph.D., Changqing Wang, M.D., Eric Wieder, Ph.D., Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2007) 110 (11): 4900.
https://doi.org/10.1182/blood.V110.11.4900.4900
Published: 2007
Journal Articles

Characterization of optimal T Cell/Dendritic Cell (DC) Co-Culture Conditions for Ex Vivo Expansion of Antigen-Specific Human T Cells.

Krishna V. Komanduri, MD, Michael Thomas, Lisa S. St. John, Ph.D., Dongxia Xing, Ph.D., William Decker, Ph.D., Simon Robinson, Ph.D., Hong Yang, Ph.D., Jeffrey J. Molldrem, M.D., Richard E. Champlin, M.D., John D. McMannis, Ph.D., Elizabeth J. Shpall, M.D.
Journal: Blood
Blood (2006) 108 (11): 3654.
https://doi.org/10.1182/blood.V108.11.3654.3654
Published: 2006
Journal Articles

Delayed Immune Recovery after Umbilical Cord Blood Transplantation (UCBT) Is Characterized by Thymic Regeneration Failure.

Krishna V. Komanduri, MD, Lisa S. St. John, Ph.D., Susan Bryan, Sean Martin, John D. McMannis, Ph.D., Jeffrey J. Molldrem, M.D., Richard E. Champlin, M.D., Laurence J. Cooper, M.D., Ph.D., Laura Worth, M.D., Demetrios Petropoulos, M.D., Daniel R. Couriel, M.D., Marcos de Lima, M.D., Elizabeth J. Shpall, M.D.
Journal: Blood
Blood (2006) 108 (11): 312.
https://doi.org/10.1182/blood.V108.11.312.312
Published: 2006
Journal Articles

IgG, IgA and IgM Autoantibodies to GM-CSF Are Present in AML, CML and MDS Patients and IgG Titer Is Associated with Disease Progression.

Anna Sergeeva, Ph.D., Yoko Ono, M.D., Rosa Rios, Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2004) 104 (11): 1071.
https://doi.org/10.1182/blood.V104.11.1071.1071
Published: 2004
Journal Articles

Antigen Cross-Presentation Allows the PR1 Leukemia-Associated Antigen To Be Processed from Both Proteinase 3 and Neutrophil Elastase to Prime T Cells.

Yoko Ono, M.D., Yukio Kondo, M.D., Anna Sergeeva, Ph.D., Olanike Akande, Pariya Sukhmalchandra, Sijie Lu, Ph.D., Eric Wieder, Ph.D., Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2004) 104 (11): 3245.
https://doi.org/10.1182/blood.V104.11.3245.3245
Published: 2004