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Journal Articles

Risk Score Generated from Ara-C Metabolic Pathway Predicts Leukemic Cell Intracellular Ara-CTP Levels in AML-97 Pediatric Patients

Abdelrahman Elsayed, BSc, MSc, Kristine R Crews, PharmD, Xueyuan Cao, PhD, Jeffrey E Rubnitz, MD PhD, Stanley Pounds, PhD, Jatinder Lamba, PhD

Blood (2017) 130 (Supplement 1): 2666.

https://doi.org/10.1182/blood.V130.Suppl_1.2666.2666

Published: 2017

Journal Articles

Global and Targeted Metabolic Profiling Identifies Metabolic Markers for FLT3-ITD in Pediatric AML Patients

Bradley Stockard, PharmD, Joy Guingab, PhD, Timothy Garrett, PhD, Stanley Pounds, PhD, Jeffrey E Rubnitz, MD PhD, Jatinder Lamba, PhD

Blood (2017) 130 (Supplement 1): 5105.

https://doi.org/10.1182/blood.V130.Suppl_1.5105.5105

Published: 2017

Journal Articles

Genome-Wide Association Study (GWAS) Identifies SNPs in GPR56 and IGF1R Predictive of Leukemic Cell In Vitro cytarabine Sensitivity in Pediatric AML

Salma Bargal, BSPharm, Roya Rafiee, PhD, Kristine R Crews, PharmD, Xueyuan Cao, PhD, Jeffrey E Rubnitz, MD PhD, Stanley Pounds, PhD, Jatinder Lamba, PhD

Blood (2017) 130 (Supplement 1): 1426.

https://doi.org/10.1182/blood.V130.Suppl_1.1426.1426

Published: 2017

Journal Articles

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

Kim Klein, MD MSc, Valerie de Haas, MD PhD, Jonas Abrahamsson, MD PhD, Todd A Alonzo, PhD, Brenda Gibson, MD PhD, Christine J Harrison, PhD FRCPath, Henrik Hasle, MD PhD, Betsy A Hirsch, PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Susana C. Raimondi, PhD, Jeffrey E Rubnitz, MD PhD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2017) 130 (Supplement 1): 2671.

https://doi.org/10.1182/blood.V130.Suppl_1.2671.2671

Published: 2017

Journal Articles

Asparaginase May Affect Mercaptopurine Tolerability in the Context of Multi-Agent Therapy for Acute Lymphoblastic Leukemia

Chengcheng Liu, PhD, Deqing Pei, Cheng Cheng, PhD, Jun J Yang, PhD, Kristine R Crews, PhD, John C Panetta, PhD, Xiangjun DeMeter, Sima Jeha, MD, John Sandlund, MD, Raul C. Ribeiro, MD, Jeffrey E Rubnitz, MD PhD, Monika L. Metzger, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD

Blood (2016) 128 (22): 179.

https://doi.org/10.1182/blood.V128.22.179.179

Published: 2016

Journal Articles

Genomic Profiling Identifies Novel Mutations and Fusion Genes in Newly Diagnosed and Relapsed Pediatric FLT3-ITD-Positive AML

Daelynn R Buelow, PhD, Stanley Pounds, PhD, Yong-Dong Wang, Lei Shi, PhD, Yongjin Li, PhD, David Finkelstein, Sheila A Shurtleff, PhD, Geoffrey A. Neale, PhD, Hiroto Inaba, MD PhD, Raul C. Ribeiro, MD, Dominique Garrison, Shelley Orwick, BS, James S. Blachly, MD, John C. Byrd, MD, Karl Kroll, Tanja A. Gruber, MD PhD, Jeffrey E Rubnitz, MD PhD, Sharyn D Baker, PharmD, PhD

Blood (2016) 128 (22): 2838.

https://doi.org/10.1182/blood.V128.22.2838.2838

Published: 2016

Journal Articles

Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination with Fludarabine and Cytarabine in Pediatric Patients with Relapsed or Refractory AML

Jeffrey E Rubnitz, MD PhD, Ronda Kaufman, PhD, Raul C. Ribeiro, MD, Boris Klebanov, MA, MS, Joel Ellis, PhD, Yosef Landesman, PhD, Hagop Youssoufian, MD, Tami Rashal, MD, Sharon Shacham

Blood (2015) 126 (23): 1345.

https://doi.org/10.1182/blood.V126.23.1345.1345

Published: 2015

Journal Articles

Acute Appendicitis in Children with Leukemia: Unique Diagnostic Process, Management, and Outcome

Melissa Perrino, MD, Israel Fernandez-Pineda, MD, Yinmei Zhou, MS, John Sandoval, MD, Sima Jeha, MD, Jeffrey E Rubnitz, MD PhD, Ching-Hon Pui, MD, Hiroto Inaba, MD PhD

Blood (2015) 126 (23): 4872.

https://doi.org/10.1182/blood.V126.23.4872.4872

Published: 2015

Journal Articles

An Analysis of CNS2 Patients with AML: Do They Require Additional Intrathecal Therapy? a Report from Children’s Oncology Group Protocols AAML0531 and 03P1 and St Jude Children’s Research Hospital Protocol AML02

Donna Johnston, MD FRCPC, Jeffrey E Rubnitz, MD PhD, Todd A. Alonzo, PhD, Robert B. Gerbing, MA, Richard Aplenc, MD PhD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD

Blood (2014) 124 (21): 277.

https://doi.org/10.1182/blood.V124.21.277.277

Published: 2014

Journal Articles

Targeted Inhibition of the MLL Transcriptional Complex By Proteosome Inhibitors Elicits a High Response Rate in Relapsed/Refractory MLL Rearranged Leukemia

Cary Koss, BS, Stephanie Nance, PhD, Michele Connelly, MS, Jing Ma, PhD, Anang Shelat, PhD, Anitria Cotton, BS, Qi An, MS, Cheng Cheng, PhD, Monika L. Metzger, MD MS, Sima Jeha, MD, Jeffrey E Rubnitz, MD PhD, James R Downing, MD, R. Kiplin Guy, PhD, Tanja A Gruber, MD PhD

Blood (2014) 124 (21): 972.

https://doi.org/10.1182/blood.V124.21.972.972

Published: 2014

Journal Articles

Clinical Impact of Additional Cytogenetic Aberrations, cKIT- and RAS Mutations and Other Factors in Pediatric t(8;21)-AML

Blood (2014) 124 (21): 481.

https://doi.org/10.1182/blood.V124.21.481.481

Published: 2014

Journal Articles

Tolerability of 6-Mercaptopurine (6MP) in Patients with Thiopurine Methyltransferase ( TPMT ) Heterozygosity in the Context of Multi-Agent Therapy for Acute Lymphoblastic Leukemia (ALL)

Chengcheng Liu, Deqing Pei, MS, Cheng Cheng, PhD, Jun J. Yang, PhD, Kristine Crews, PharmD, Wenjian Yang, PhD, Seth E. Karol, MD, Sima Jeha, MD, John T. Sandlund, MD, Raul C Ribeiro, MD, Jeffrey E Rubnitz, MD PhD, Monika L. Metzger, MD MS, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD

Blood (2014) 124 (21): 3722.

https://doi.org/10.1182/blood.V124.21.3722.3722

Published: 2014

Journal Articles

Prognostic Factors For Children With Acute Myeloid Leukemia Who Achieve Minimal Residual Disease-Negative Status After Induction Therapy

Seth E Karol, MD, Elaine Coustan-Smith, MS, Xueyuan Cao, PhD, Sheila A Shurtleff, PhD, Susana C Raimondi, PhD, John K Choi, MD, PhD, Raul C Ribeiro, MD, Gary V Dahl, MD, W Paul Bowman, MD, Jeffrey W Taub, MD, Barbara Degar, MD, Wing Leung, MD, PhD, James R Downing, MD, Ching-Hon Pui, MD, Jeffrey E Rubnitz, MD, PhD, Dario Campana, MD, PhD, Hiroto Inaba, MD, PhD

Blood (2013) 122 (21): 490.

https://doi.org/10.1182/blood.V122.21.490.490

Published: 2013

Journal Articles

High-Resolution Genomic Profiling of Adult and Pediatric Core Binding Factor Acute Myeloid Leukemia Reveals New Recurrent Genomic Aberrations

Blood (2010) 116 (21): 849.

https://doi.org/10.1182/blood.V116.21.849.849

Published: 2010

Journal Articles

Clinical Activity, Pharmacokinetics, and Pharmacodynamics of Sorafenib In Pediatric Acute Myeloid Leukemia.

Hiroto Inaba, MD, PhD, Jeffrey E Rubnitz, MD, PhD, Elaine Coustan-Smith, MS, Lie Li, Brian D Furmanski, PhD, Gerard P Mascara, Sheila A Shurtleff, PhD, Stanley B Pounds, PhD, Ching-Hon Pui, MD, Raul C Ribeiro, MD, Dario Campana, MD, PhD, Sharyn D Baker, PharmD, PhD

Blood (2010) 116 (21): 1073.

https://doi.org/10.1182/blood.V116.21.1073.1073

Published: 2010

Journal Articles

Improved Prognosis for Older Adolescents with Acute Lymphoblastic Leukemia

Blood (2010) 116 (21): 498.

https://doi.org/10.1182/blood.V116.21.498.498

Published: 2010

Journal Articles

Excellent Outcome for ETV6/RUNX1 -Positive Childhood Acute Lymphoblastic Leukemia (ALL) with Contemporary Therapy

Blood (2010) 116 (21): 495.

https://doi.org/10.1182/blood.V116.21.495.495

Published: 2010

Journal Articles

Inhibition of Class I PI3K Isoforms Restores the Sensitivity of Acute Myelogenous Leukemia Cells to Multi-Tyrosine Kinase Inhibitors in the Bone Marrow Microenvironment.

Akira Shimada, MD, PhD, Hongmei Niu, MD.PhD, Shelley Orwick, Hiroto Inaba, MD, PhD, Jeffrey E Rubnitz, MD, PhD, Dario Campana, MD, PhD, Sharyn D Baker, PharmD.PhD.

Blood (2009) 114 (22): 1734.

https://doi.org/10.1182/blood.V114.22.1734.1734

Published: 2009

Journal Articles

High-Resolution Genome-Wide Profiling of DNA Copy Number Abnormalities and Gene Resequencing in Pediatric Acute Myeloid Leukemia (AML).

Ina Radtke, PhD, Charles G. Mullighan, MD, PhD, Masami Ishii, MD, PhD, Jing Ma, PhD, Xiaoping Su, PhD, Salil Goorha, MD, Ramapriya Ganti, PhD, Zhongling Cai, Letha A. Phillips, Stanley B. Pounds, PhD, James Dalton, Susana C. Raimondi, PhD, Jeffrey E. Rubnitz, MD, PhD, Raul C. Ribeiro, MD, Sheila A. Shurtleff, PhD, James R. Downing, MD

Blood (2007) 110 (11): 103.

https://doi.org/10.1182/blood.V110.11.103.103

Published: 2007

Journal Articles

Childhood Mixed Lineage Leukemia: The St. Jude Experience.

Mihaela Onciu, MD, Ching-Hon Pui, MD, Fred G. Behm, MD, Bassem I. Razzouk, MD, Raul C. Ribeiro, MD, Jeffrey E. Rubnitz, MD, PhD

Blood (2007) 110 (11): 1844.

https://doi.org/10.1182/blood.V110.11.1844.1844

Published: 2007

NARROW

Risk Score Generated from Ara-C Metabolic Pathway Predicts Leukemic Cell Intracellular Ara-CTP Levels in AML-97 Pediatric Patients

Global and Targeted Metabolic Profiling Identifies Metabolic Markers for FLT3-ITD in Pediatric AML Patients

Genome-Wide Association Study (GWAS) Identifies SNPs in GPR56 and IGF1R Predictive of Leukemic Cell In Vitro cytarabine Sensitivity in Pediatric AML

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

Asparaginase May Affect Mercaptopurine Tolerability in the Context of Multi-Agent Therapy for Acute Lymphoblastic Leukemia

Genomic Profiling Identifies Novel Mutations and Fusion Genes in Newly Diagnosed and Relapsed Pediatric FLT3-ITD-Positive AML

Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination with Fludarabine and Cytarabine in Pediatric Patients with Relapsed or Refractory AML

Acute Appendicitis in Children with Leukemia: Unique Diagnostic Process, Management, and Outcome

An Analysis of CNS2 Patients with AML: Do They Require Additional Intrathecal Therapy? a Report from Children’s Oncology Group Protocols AAML0531 and 03P1 and St Jude Children’s Research Hospital Protocol AML02

Targeted Inhibition of the MLL Transcriptional Complex By Proteosome Inhibitors Elicits a High Response Rate in Relapsed/Refractory MLL Rearranged Leukemia

Clinical Impact of Additional Cytogenetic Aberrations, cKIT- and RAS Mutations and Other Factors in Pediatric t(8;21)-AML

Tolerability of 6-Mercaptopurine (6MP) in Patients with Thiopurine Methyltransferase ( TPMT ) Heterozygosity in the Context of Multi-Agent Therapy for Acute Lymphoblastic Leukemia (ALL)

Prognostic Factors For Children With Acute Myeloid Leukemia Who Achieve Minimal Residual Disease-Negative Status After Induction Therapy

High-Resolution Genomic Profiling of Adult and Pediatric Core Binding Factor Acute Myeloid Leukemia Reveals New Recurrent Genomic Aberrations

Clinical Activity, Pharmacokinetics, and Pharmacodynamics of Sorafenib In Pediatric Acute Myeloid Leukemia.

Improved Prognosis for Older Adolescents with Acute Lymphoblastic Leukemia

Excellent Outcome for ETV6/RUNX1 -Positive Childhood Acute Lymphoblastic Leukemia (ALL) with Contemporary Therapy

Inhibition of Class I PI3K Isoforms Restores the Sensitivity of Acute Myelogenous Leukemia Cells to Multi-Tyrosine Kinase Inhibitors in the Bone Marrow Microenvironment.

High-Resolution Genome-Wide Profiling of DNA Copy Number Abnormalities and Gene Resequencing in Pediatric Acute Myeloid Leukemia (AML).

Childhood Mixed Lineage Leukemia: The St. Jude Experience.

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American Society of Hematology

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American Society of Hematology

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