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Journal Articles

Evaluation of Extrinsic and Intrinsic Cues Involved in BCR-ABL-Induced Leukemogenesis

Pallavi Suhas Sontakke, MSC, Richard W.J. Groen, PhD, Katarzyna Koczula, MSC, Jennifer Jaques, Huipin Yuan, PhD, Ulrich Günther, PhD, Anton C. Martens, PhD, Edo Vellenga, MD PhD, Jan J. Schuringa, PhD

Blood (2014) 124 (21): 515.

https://doi.org/10.1182/blood.V124.21.515.515

Published: 2014

Journal Articles

Identification of the TAK1-NF-κB Axis As Critical Regulator of AML Stem and Progenitor Cell Survival.

Matthieu C.J. Bosman, Jan J. Schuringa, Wim J. Quax, PhD, Edo Vellenga

Blood (2012) 120 (21): 2982.

https://doi.org/10.1182/blood.V120.21.2982.2982

Published: 2012

Journal Articles

Reconstructing the Human Hematopoietic Niche: Opportunities for Studying Normal and Malignant Hematopoiesis,

Richard W Groen, PhD, Willy A Noort, PhD, Reinier Raymakers, MD, PhD, Henk-Jan Prins, Msc, Linda Aalders, Frans M Hofhuis, Berris van Kessel, Petra Moerer, Henk Rozemuller, PhD, Jan J. Schuringa, PhD, Joost de Bruijn, PhD, Michel de Weers, PhD, Paul W.H.I. Parren, PhD, Henk M. Lokhorst, MD, Tuna Mutis, MD PhD, Anton CM Martens, PhD

Blood (2011) 118 (21): 3412.

https://doi.org/10.1182/blood.V118.21.3412.3412

Published: 2011

Journal Articles

CITED2 Modulates Differentiation and Proliferation of Normal and Leukemic Hematopoietic Stem and Progenitor Cells Downstream of PU.1

Hein Schepers, Ph.D, Patrick M. Korthuis, Jan J. Schuringa, PhD, Gerald de Haan, Ph.D, Edo Vellenga, PhD

Blood (2011) 118 (21): 922.

https://doi.org/10.1182/blood.V118.21.922.922

Published: 2011

Journal Articles

NF-κB and MCL-1 Are Important Determinants for the Effectiveness of Bortezomib In CD34 + AML Versus CD34 − AML Cells

Matthieu C.J. Bosman, Jan J. Schuringa, PhD, Wim J. Quax, PhD, Edo Vellenga, PhD

Blood (2011) 118 (21): 1420.

https://doi.org/10.1182/blood.V118.21.1420.1420

Published: 2011

Journal Articles

Loss of Stem Cell Quiescence and Impaired Stem Cell Function of CD34 + /CD38 low Cells One Year Following Autologous Stem Cell Transplantation

Carolien M Woolthuis, Annet Z Vos, Gerwin Huls, Joost TM de Wolf, Jan J. Schuringa, PhD, Edo Vellenga, PhD

Blood (2011) 118 (21): 1893.

https://doi.org/10.1182/blood.V118.21.1893.1893

Published: 2011

Journal Articles

Gene Expression Profiling In Leukemic Stem Cell-Enriched AML CD34 + Cell Fraction Identifies Target Genes That Predict Prognosis In Normal Karyotype AML

Carolien M Woolthuis, Hendrik JM de Jonge, Annet Z Vos, Andre B Mulder, MD, Eva van den Berg, P.M. Kluin, MD, PhD, Karen van der Weide, Evelina S. De Bont, MD, PhD, Geert A Huls, MD, PhD, Edo Vellenga, MD, PhD, Jan J. Schuringa, PhD

Blood (2010) 116 (21): 952.

https://doi.org/10.1182/blood.V116.21.952.952

Published: 2010

Journal Articles

In Vivo Treatment of AML Patients with High-Dose Simvastatin Inhibits Geranylgeranylation In AML Cells

Karen van der Weide, Susan D.P.W.M. de Jonge-Peeters, Gerwin A. Huls, MD, PhD, Rudolf S.N. Fehrmann, Jan J. Schuringa, PhD, Folkert Kuipers, PhD, Elisabeth G.E. de Vries, MD, PhD, Edo Vellenga, MD, PhD

Blood (2010) 116 (21): 3280.

https://doi.org/10.1182/blood.V116.21.3280.3280

Published: 2010

Journal Articles

Hematopoietic Stem Cells, but Not Progenitors, Are the Exclusive Target for STAT5-Induced Long-Term Self-Renewal.

Szabolcs Fatrai, Albertus T.J. Wierenga, Edo Vellenga, Simon M. G. J. Daenen, Jan J. Schuringa

Blood (2008) 112 (11): 1347.

https://doi.org/10.1182/blood.V112.11.1347.1347

Published: 2008

Journal Articles

Long-Term Expansion and Self Renewal Is Contained in the CD34+, but Not the CD34- Subfraction of Nucleophosmin Mutated Acute Myeloid Leukemia Cells.

Carolien Woolthuis, Lina Han, Djoke van Gosliga, Philip Kluin, MD, PhD, Edo Vellenga, MD, PhD, Jan J. Schuringa, PhD, Geert Huls, MD, PhD

Blood (2008) 112 (11): 1349.

https://doi.org/10.1182/blood.V112.11.1349.1349

Published: 2008

Journal Articles

Muc1 Expression Identifies Human Self-Renewing Stem/Progenitor Populations and Is Elevated in AML CD34+ Cells.

Szabolcs Fatrai, Simon M.G.J. Daenen, Edo Vellenga, Jan J. Schuringa

Blood (2007) 110 (11): 4040.

https://doi.org/10.1182/blood.V110.11.4040.4040

Published: 2007

NARROW

Evaluation of Extrinsic and Intrinsic Cues Involved in BCR-ABL-Induced Leukemogenesis

Identification of the TAK1-NF-κB Axis As Critical Regulator of AML Stem and Progenitor Cell Survival.

Reconstructing the Human Hematopoietic Niche: Opportunities for Studying Normal and Malignant Hematopoiesis,

CITED2 Modulates Differentiation and Proliferation of Normal and Leukemic Hematopoietic Stem and Progenitor Cells Downstream of PU.1

NF-κB and MCL-1 Are Important Determinants for the Effectiveness of Bortezomib In CD34 + AML Versus CD34 − AML Cells

Loss of Stem Cell Quiescence and Impaired Stem Cell Function of CD34 + /CD38 low Cells One Year Following Autologous Stem Cell Transplantation

Gene Expression Profiling In Leukemic Stem Cell-Enriched AML CD34 + Cell Fraction Identifies Target Genes That Predict Prognosis In Normal Karyotype AML

In Vivo Treatment of AML Patients with High-Dose Simvastatin Inhibits Geranylgeranylation In AML Cells

Hematopoietic Stem Cells, but Not Progenitors, Are the Exclusive Target for STAT5-Induced Long-Term Self-Renewal.

Long-Term Expansion and Self Renewal Is Contained in the CD34+, but Not the CD34- Subfraction of Nucleophosmin Mutated Acute Myeloid Leukemia Cells.

Muc1 Expression Identifies Human Self-Renewing Stem/Progenitor Populations and Is Elevated in AML CD34+ Cells.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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