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James E. Bradner, M.D
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Journal Articles

Targeting The PRMT5 Enzyme To Induce γ -Globin Gene Derepression In Sickle Cell Anemia

Necrisha Roach, MSc., Matthew Cannon, Dalia El-Gamal, PhD, Payal C Desai, MD, Eric H. Kraut, MD, James E. Bradner, M.D., Rosa Lapalombella, PhD, Robert A. Baiocchi, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 1007.
https://doi.org/10.1182/blood.V122.21.1007.1007
Published: 2013
Journal Articles

The Interaction Between DOT1L and AF10 Is Required for H3K79 Dimethylation and MLL-AF9 Leukemia

Aniruddha J Deshpande, Liying Chen, Kathrin M Bernt, MD, Stuart Dias, Deepti Banka, Amit U. Sinha, David Chen, Natalie Punt, James E. Bradner, M.D., Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 401.
https://doi.org/10.1182/blood.V120.21.401.401
Published: 2012
Journal Articles

Discovery and Characterization of Macrocyclic Thiopeptide Proteasome Inhibitors for Hematologic Malignancies

Sridevi Ponduru, M.D., Raymond Moellering, Edward Greenberg, John Paul Ying-Ching Shen, M.D., Benjamin Z Stanton, James E. Bradner, M.D
Journal: Blood
Blood (2008) 112 (11): 3669.
https://doi.org/10.1182/blood.V112.11.3669.3669
Published: 2008
Journal Articles

The Rationale for Combined Proteasome and Autophagy Inhibition in Multiple Myeloma Established Using Novel Translational Platforms

John Paul Y.C. Shen, M.D., Sanjay Divakaran, B.S., Sridevi Ponduru, M.D., Dan T. Vogl, MD, Ravi K. Amaravadi, M.D., James E. Bradner, M.D.
Journal: Blood
Blood (2008) 112 (11): 2755.
https://doi.org/10.1182/blood.V112.11.2755.2755
Published: 2008
Journal Articles

Targeting Histone Deacetylase 6 and the Aggresome Pathway in Acute Lymphoblastic Leukemia Cells.

Augustin Rodriguez-Gonzalez, PhD, James Ch’ng, Alan K. Ikeda, M.D., Tara Lin, M.D., Bita Bahrami, Ralph Mazitschek, Ph.D., James E. Bradner, M.D., Cecilia Fu, M.D., Kathleen M. Sakamoto, M.D., Ph.D.
Journal: Blood
Blood (2007) 110 (11): 1602.
https://doi.org/10.1182/blood.V110.11.1602.1602
Published: 2007