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James A Kennedy, MD PhD
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Journal Articles

HSCs Fated to Progress to Blast Phase Can be Detected in Myelofibrosis Patients Several Years Prior to Leukemic Transformation

Jenny M. Ho, MD, Jessie J.F. Medeiros, BSc, Michelle Chan-Seng-Yue, Lauren Hummel, BSc, Andrea Arruda, Amanda Mitchell, PhD, Caroline J McNamara, MBBS, James A Kennedy, MD PhD, Anne Tierens, MD PhD, Dawn Maze, MDFRCPC,MSc, Hubert Tsui, MD PhD, Mark D. Minden, MD PhD, Vikas Gupta, MD FRCP, FRCPath, John E. Dick, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1676.
https://doi.org/10.1182/blood-2019-130923
Published: 2019
Journal Articles

Sirpαfc Treatment Targets Human Acute Myeloid Leukemia Stem Cells

Oleksandr Galkin, PhD, Jessica McLeod, BSc, James A Kennedy, MD PhD, Liqing Jin, MD, Nathan Mbong, Mark Wong, PhD, Bob Uger, PhD, Mark D. Minden, MD PhD, Jayne S Danska, PhD, Jean C.Y. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3906.
https://doi.org/10.1182/blood-2019-131018
Published: 2019
Journal Articles

Chromatin Accessibility Identifies CTCF As a Gatekeeper of Stemness Functions in Human Hematopoietic Development

Naoya Takayama, MD PhD, Alex Murison, PhD, Shin-ichiro Takayanagi, PhD, Sasan Zandi, MD PhD, Nadia Penrod, PhD, Amanda Mitchel, James A. Kennedy, MD PhD, Stanley W.K. Ng, MSc, Stephanie Zhi-Juan Xie, PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Mathieu Lupien, PhD
Journal: Blood
Blood (2016) 128 (22): 3873.
https://doi.org/10.1182/blood.V128.22.3873.3873
Published: 2016
Journal Articles

Impact of Genomic Alterations on Outcomes in Myelofibrosis Patients Undergoing JAK1/2 Inhibitor Therapy

Jay Spiegel, MD, Caroline Jane McNamara, MBBS, Andrea Arruda, MSc., Tony Panzarella, BSc MSc, James A. Kennedy, MD PhD, Tracy L. Stockley, PhD, Mahadeo Sukhai, BSc, MSc, PhD, Mariam Thomas, PhD, Justyna Bartoszko, MD, Jenny M. Ho, MD, Nancy Siddiq, RN, BScN, Aaron D. Schimmer, MD PhD, Andre C. Schuh, MD FRCPC, Hassan Sibai, MD, Karen W.L. Yee, MD, Jaime O. Claudio, PhD, Rebecca Devlin, PhD, Mark D. Minden, MD PhD, Suzanne Kamel-Reid, PhD DABMG, FACMG, Vikas Gupta, MD FRCP, FRCPath
Journal: Blood
Blood (2016) 128 (22): 4263.
https://doi.org/10.1182/blood.V128.22.4263.4263
Published: 2016
Journal Articles

Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance

Eric R. Lechman, PhD, Bernhard Gentner, MD, Peter van Galen, Stanley Wai-Kwong Ng, Kolja Eppert, PhD, Rene Marke, Liran Slush, MD, James A. Kennedy, MD PhD, Amanda Mitchell, PhD, Weihsu Claire Chen, PhD, Veronique Voisin, PhD, Gary Bader, PhD, Mark D. Minden, MD, PhD, Jun Lu, PhD, Jean C.Y. Wang, MD PhD, Luigi Naldini, John E. Dick, PhD
Journal: Blood
Blood (2013) 122 (21): 1647.
https://doi.org/10.1182/blood.V122.21.1647.1647
Published: 2013
Journal Articles

Leukemic Engraftment In NOD. SCID Mice Is Correlated With Clinical Parameters and Predicts Outcome In Human AML

James A. Kennedy, MD PhD, Amanda Mitchell, PhD, Weihsu Claire Chen, PhD, Jessica McLeod, Andreea C. Popescu, BSc, Andrea Arruda, MSc, Mark D. Minden, MD PhD, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2013) 122 (21): 50.
https://doi.org/10.1182/blood.V122.21.50.50
Published: 2013
Journal Articles

DNMT3a Mutations Define a Pre-Leukemic Stem Cell Reservoir In Human Acute Myeloid Leukemia

Liran I. Shlush, MD, PhD, Sasan Zandi, PhD, MD, Amanda Mitchell, PhD, Weihsu Claire Chen, PhD, McLeod Jessica, Monica Doedens, Medeiros Jessie, Marke Rene, McPherson J John, PhD, Thomas J Hudson, MD, Brown Andrew, PhD, Trinh M Quang, Lincoln D Stein, James A. Kennedy, MD PhD, Mark D. Minden, MD, PhD, Jean C.Y. Wang, MD PhD, John E Dick, PhD
Journal: Blood
Blood (2013) 122 (21): 487.
https://doi.org/10.1182/blood.V122.21.487.487
Published: 2013
Journal Articles

Comparing Human Fetal Liver, Cord Blood and Adult Bone Marrow Stem/Progenitor Hematopoietic Cells As Cells of Origin of Human MLL Leukemias

Sara Berthiaume, James A Kennedy, MD, PhD, Anne Bergeron, PhD, Mathieu Belanger, John E. Dick, PhD, Frederic Barabe, MD
Journal: Blood
Blood (2011) 118 (21): 2956.
https://doi.org/10.1182/blood.V118.21.2956.2956
Published: 2011
Journal Articles

Effects of LMO2 on Human T-Cell Development Are Modulated by Notch Signaling

James A Kennedy, MD, PhD, Renata Teixeira, Sara Berthiaume, Frederic Barabe, MD
Journal: Blood
Blood (2011) 118 (21): 2470.
https://doi.org/10.1182/blood.V118.21.2470.2470
Published: 2011