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J Kyle Bruner
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Journal Articles

SHP2 Inhibition Overcomes Adaptive and Acquired Resistance to FLT3 TKI to Improve Efficacy Against FLT3/ITD AML

Tessa Seale, Li Li, J. Kyle Bruner, Bao Nguyen, Mark J. Levis, Christine Pratilas, Donald Small
Journal: Blood
Blood (2023) 142 (Supplement 1): 2790.
https://doi.org/10.1182/blood-2023-184338
Published: 2023
Journal Articles

All- trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD + leukemia stem cells in vitro and in vivo

Hayley S. Ma, Sarah M. Greenblatt, Courtney M. Shirley, Amy S. Duffield, J. Kyle Bruner, Li Li, Bao Nguyen, Eric Jung, Peter D. Aplan, Gabriel Ghiaur, Richard J. Jones, Donald Small
Journal: Blood
Blood (2016) 127 (23): 2867–2878.
https://doi.org/10.1182/blood-2015-05-646786
Published: 2016
Includes: Supplemental data
Journal Articles

FLT3 Inhibition and Retinoid Signaling Overcome Stromal Protection to Target FLT3/ITD-Expressing Leukemia Stem Cells in the Bone Marrow Microenvironment

Hayley S Ma, PhD, Megan E McCray, BA, Courtney M Shirley, PhD, Amy S. Duffield, MD PhD, J Kyle Bruner, Li Li, PhD, Bao Nguyen, M.S., Sarah Greenblatt, PhD, Eric Jung, BS, Peter D. Aplan, MD, Richard J Jones, MD, Donald Small, MD PhD, Gabriel Ghiaur, MD PhD
Journal: Blood
Blood (2015) 126 (23): 790.
https://doi.org/10.1182/blood.V126.23.790.790
Published: 2015