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Journal Articles

Inhibition of Neutrophil Extracellular Trap Release through the Disruption of PAD4 Leads to Decreased Neutrophil and Platelet Accumulation at Sites of Venular Vascular Injury in a Murine Model of Heparin-Induced Thrombocytopenia

Kandace Gollomp, MD, Vincent Hayes, Ian Johnston, BS, Minna Kim, Guohua Zhao, Lubica Rauova, MD PhD, Mortimer Poncz, MD

Blood (2017) 130 (Supplement 1): 2268.

https://doi.org/10.1182/blood.V130.Suppl_1.2268.2268

Published: 2017

Journal Articles

Platelet Factor 4 (PF4)-Mediated Neutrophil Extracellular Trap Compaction Limits Endothelial Injury and Promotes Survival Following Lipopolysaccharide Challenge

Kandace Gollomp, MD, Ian Johnston, BS, Minna Kim, Li Zhai, Guohua Zhao, M. Anna Kowalska, PhD, Mortimer Poncz, MD

Blood (2017) 130 (Supplement 1): 997.

https://doi.org/10.1182/blood.V130.Suppl_1.997.997

Published: 2017

Journal Articles

Platelet Factor 4 Binds to Released Von Willebrand Factor Strands from Injured Endothelium and Forms a Prothrombotic HIT Antigenic Complex

Ian Johnston, BS, Jose A. Lopez, MD, Douglas B. Cines, MD, Lubica Rauova, MD PhD, Mortimer Poncz, MD

Blood (2017) 130 (Supplement 1): 2310.

https://doi.org/10.1182/blood.V130.Suppl_1.2310.2310

Published: 2017

Journal Articles

A Special Role for Neutrophil Extracellular Traps (NETs) and Neutrophils in the Prothombotic Nature of Heparin-Induced Thrombocytopenia

Kandace Gollomp, MD, Ian Johnston, BS, Lubica Rauova, MD PhD, Douglas B. Cines, MD, M. Anna Kowalska, PhD, Mortimer Poncz, MD

Blood (2016) 128 (22): 1023.

https://doi.org/10.1182/blood.V128.22.1023.1023

Published: 2016

Journal Articles

Platelet Release from Infused CD34 + -Derived Human Megakaryocytes: Lessons from a Natural-Occurring Platelet Bioreactor

Ian Johnston, BS, Vincent M Hayes, BS, Jing Dai, MD PhD, Danuta Jadwiga Jarocha, PhD, Paul Kubes, PhD, Mortimer Poncz, MD, Lubica Rauova, MD PhD

Blood (2016) 128 (22): 1375.

https://doi.org/10.1182/blood.V128.22.1375.1375

Published: 2016

Journal Articles

Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy

Carlos Hipolito Villa, MD PhD, Daniel Pan, PhD, Ian Johnston, BS, Colin F Greineder, MD PhD, Marion E. Reid, PhD, Douglas B. Cines, MD, Mortimer Poncz, MD, Don L. Siegel, MD, PhD,, Vladimir R Muzykantov, MD PhD

Blood (2016) 128 (22): 701.

https://doi.org/10.1182/blood.V128.22.701.701

Published: 2016

Journal Articles

Simultaneous Replacement of Endothelial Thrombomodulin and Plasma Protein C: A Novel Therapeutic Strategy for Sepsis-Induced Disseminated Intravascular Coagulation

Colin F Greineder, MDPhD, Ian Johnston, BS, Carlos Hipolito Villa, MD PhD, Douglas B. Cines, MD, Mortimer Poncz, MD, Vladimir R Muzykantov, MD PhD

Blood (2016) 128 (22): 2613.

https://doi.org/10.1182/blood.V128.22.2613.2613

Published: 2016

Journal Articles

A Targeted Photochemical Microfluidic Vascular Injury Model for in Vitro Thrombosis Studies: Usage in Heparin-Induced Thrombocytopenia (HIT)

Ian Johnston, BS, Vincent M Hayes, BS, Douglas B. Cines, Mortimer Poncz, MD

Blood (2015) 126 (23): 212.

https://doi.org/10.1182/blood.V126.23.212.212

Published: 2015

Journal Articles

A Microfluidic Model of Microvascular Inflammation: Characterization and Testing of Endothelial-Targeted Therapeutics

Colin F Greineder, MDPhD, Ian Johnston, BS, Carlos Hipolito Villa, MD PhD, Douglas B. Cines, MD, Mortimer Poncz, MD, Vladimir R Muzykantov, MDPhD

Blood (2015) 126 (23): 3454.

https://doi.org/10.1182/blood.V126.23.3454.3454

Published: 2015

Journal Articles

Thrombomodulin Fusion Proteins Coupled to Human Erythrocytes Demonstrate Anti-Thrombotic and Anti-Inflammatory Activity

Carlos Hipolito Villa, MD PhD, Colin F Greineder, MDPhD, Ian Johnston, BS, Daniel Pan, PhD, Ronald Carnemolla, PhD, Douglas B. Cines, MD, Mortimer Poncz, MD, Don L. Siegel, MD, PhD,, Vladimir R Muzykantov, MDPhD

Blood (2015) 126 (23): 3493.

https://doi.org/10.1182/blood.V126.23.3493.3493

Published: 2015

Journal Articles

New Insights into the Prothrombotic State of Heparin-Induced Thrombocytopenia (HIT) Using a Novel Microfluidic System: The Endothelial Lining and “Rolling Barrage” of Activation

Vincent Hayes, Ian Johnston, BS, Douglas B. Cines, MD, Lubica Rauova, MD PhD, Mortimer Poncz, MD

Blood (2014) 124 (21): 574.

https://doi.org/10.1182/blood.V124.21.574.574

Published: 2014

Journal Articles

A Proposed Role for Platelet Factor 4 in Histone Pathobiology in Sepsis

M. Anna Kowalska, PhD, Guohua Zhao, PhD, Ian Johnston, BS, Elsa Treffeisen, BA, Fatoumata Diarra, Sriram Krishnaswamy, PhD, Mortimer Poncz, MD

Blood (2014) 124 (21): 98.

https://doi.org/10.1182/blood.V124.21.98.98

Published: 2014

NARROW

Inhibition of Neutrophil Extracellular Trap Release through the Disruption of PAD4 Leads to Decreased Neutrophil and Platelet Accumulation at Sites of Venular Vascular Injury in a Murine Model of Heparin-Induced Thrombocytopenia

Platelet Factor 4 (PF4)-Mediated Neutrophil Extracellular Trap Compaction Limits Endothelial Injury and Promotes Survival Following Lipopolysaccharide Challenge

Platelet Factor 4 Binds to Released Von Willebrand Factor Strands from Injured Endothelium and Forms a Prothrombotic HIT Antigenic Complex

A Special Role for Neutrophil Extracellular Traps (NETs) and Neutrophils in the Prothombotic Nature of Heparin-Induced Thrombocytopenia

Platelet Release from Infused CD34 + -Derived Human Megakaryocytes: Lessons from a Natural-Occurring Platelet Bioreactor

Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy

Simultaneous Replacement of Endothelial Thrombomodulin and Plasma Protein C: A Novel Therapeutic Strategy for Sepsis-Induced Disseminated Intravascular Coagulation

A Targeted Photochemical Microfluidic Vascular Injury Model for in Vitro Thrombosis Studies: Usage in Heparin-Induced Thrombocytopenia (HIT)

A Microfluidic Model of Microvascular Inflammation: Characterization and Testing of Endothelial-Targeted Therapeutics

Thrombomodulin Fusion Proteins Coupled to Human Erythrocytes Demonstrate Anti-Thrombotic and Anti-Inflammatory Activity

New Insights into the Prothrombotic State of Heparin-Induced Thrombocytopenia (HIT) Using a Novel Microfluidic System: The Endothelial Lining and “Rolling Barrage” of Activation

A Proposed Role for Platelet Factor 4 in Histone Pathobiology in Sepsis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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