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Journal Articles

Final Report of a Phase I/II Study of Hyper-CVAD Plus RAD001 (Everolimus) in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Yanis Boumber, MD, PhD, Deborah A. Thomas, MD, Farhad Ravandi, MD, Michael E. Rytting, MD, Marian R Love, Hongbo Lu, MMSC, Rebecca Garris, BSc, Jorge E. Cortes, MD, Susan O'Brien, M.D., Jan A. Burger, MD, PhD, Hagop M. Kantarjian, MD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3567.
https://doi.org/10.1182/blood.V120.21.3567.3567
Published: 2012
Journal Articles

Leukemia Cell Mobilization with Plerixafor Plus G-CSF with Busulfan/Fludarabine and Allogeneic Hematopoietic Cell Transplantation in Patients with AML/MDS Is Associated with Decreased Complete Chimerism and GvHD, and Increased Risk of Relapse

Christopher B. Benton, MD, Marina Konopleva, MD, PhD, Rima M Saliba, PhD, Elizabeth J. Shpall, MD, Stefan O. Ciurea, Partow Kebriaei, M.D., Amin M. Alousi, M.D., Uday R. Popat, M.D., Paolo Anderlini, MD, Yago Nieto, M.D., Ph.D., Simrit Parmar, M.D., Zhihong Zeng, MD, Julianne J Chen, Gabriela Rondon, MD, Becky McMullin, RN, Rui-Yu Wang, MD, PhD, Hongbo Lu, MMSC, Wendy D. Schober, MLT (ASCP), Glenda G Woodworth, RN, Alison Gulbis, Pharm.D., Rita Cool, Wei Qiao, Peter F Thall, PhD, Michael Andreeff, MD, PhD, Richard E. Champlin
Journal: Blood
Blood (2012) 120 (21): 360.
https://doi.org/10.1182/blood.V120.21.360.360
Published: 2012
Journal Articles

Role of Connective Tissue Growth Factor (CTGF) in Survival and Chemosensitivity of Acute Lymphoblastic Leukemia

Hongbo Lu, MMSC, Venkata Lokesh Battula, Ph.D., Yuexi Shi, Richard B Lock, PhD, Suzanne Spong, Ph.D, Michael Andreeff, M.D., Ph.D., Marina Konopleva, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 2593.
https://doi.org/10.1182/blood.V118.21.2593.2593
Published: 2011
Journal Articles

Targeting the Leukemia-Associated Hypoxic Microenvironment with Hypoxia-Activated Prodrug PR-104

Juliana Benito, Ph.D., Yuexi Shi, Barbara Szymanska, Hernan Carol, Ingrid Bohem, Hongbo Lu, MMSC, Sergej Konoplev, MD, PhD, Wendy Fang, Steven M. Kornblau, MD, Patrick Zweidler-McKay, MD, PhD, William Wilson, PhD, Dario Campana, MD, PhD, Gautam Borthakur, MD, Carlos E. Bueso-Ramos, Hagop M. Kantarjian, MD, Elizabeth J. Shpall, Deborah A Thomas, MD, Craig T. Jordan, PhD, Richard B Lock, PhD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 868.
https://doi.org/10.1182/blood.V116.21.868.868
Published: 2010
Journal Articles

Targeting Connective Tissue Growth Factor (CTGF) In Acute Lymphoblastic Leukemia Pre-Clinical Models: Anti-CTGF Monoclonal Antibody Attenuates Tumor Growth In Mouse Models of ALL

Hongbo Lu, MMSC, Venkata Lokesh Battula, Ph.D., Borys Korchin, MD, Suzanne Spong, Ph.D, Martin Canizales, Ph.D, Richard B Lock, PhD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3257.
https://doi.org/10.1182/blood.V116.21.3257.3257
Published: 2010
Journal Articles

The Synergistic Effect of DNA Methylation Inhibitor 5-Azacytidine and Bcl-2 Signaling Blockade ABT-737 Combination Treatment Induce Apoptosis In AML

Yuexi Shi, Twee Tsao, Hongbo Lu, MMSC, Sergej Konoplev, MD, PhD, Wendy D. Schober, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3311.
https://doi.org/10.1182/blood.V116.21.3311.3311
Published: 2010
Journal Articles

A Phase I/II Trial of Plerixafor/G-CSF Combined with IV Bu/Flu Conditioning Regimen In AML/MDS Patients Undergoing Allogenic Stem Cell Transplantation

Marina Konopleva, MD, PhD, Zeng Zhihong, Rui-Yu Wang, MD, PhD, Peter F. Thall, PhD, Gloria McCormick, Hongbo Lu, MMSC, Julianne J Chen, Elizabeth J. Shpall, Stefan O. Ciurea, MD, Partow Kebriaei, MD, Amin M Alousi, MD, Uday Popat, MD, Paolo Anderlini, MD, Yago Nieto, MD, PhD, Simrit Parmar, M.D., Becky McMullin, Gabriela Rondon, MD, Wendy D. Schober, Alison Gulbis, Rita Cool, E. Lin, Michael Andreeff, MD, PhD, Richard Champlin
Journal: Blood
Blood (2010) 116 (21): 2358.
https://doi.org/10.1182/blood.V116.21.2358.2358
Published: 2010
Journal Articles

Role of Hypoxia and Hypoxia-Inducible-Factor 1α (HIF1A) In the BM Microenvironment-Mediated Protection of Leukemic Cells.

Rodrigo Jacamo, Juliana Benito, Ph.D., Olga Frolova, MD, PhD, Ye Chen, Hongbo Lu, MMSC, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2586.
https://doi.org/10.1182/blood.V116.21.2586.2586
Published: 2010
Journal Articles

Therapeutic Targeting of the Hypoxic Microenvironment in Acute Lymphocytic Leukemia.

Marina Konopleva, MD, PhD, Juliana Benito, PhD, Yue-Xi Shi, Sergej Konoplev, MD, PhD, Steven M. Kornblau, MD, Olga Frolova, MD, PhD, Patrick A. Zweidler-McKay, MD, PhD, YiHua Qiu, MD, MS, William R. Wilson, PhD, Dario Campana, MD, PhD, Rodrigo Jacamo, PhD, Hongbo Lu, MMSC, Wendy Fang, MD, Gautam Borthakur, MD, Carlos E. Bueso-Ramos, MD, Hagop M. Kantarjian, MD, Deborah A. Thomas, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2040.
https://doi.org/10.1182/blood.V114.22.2040.2040
Published: 2009
Journal Articles

Expression and Function of the CXCR7 Chemokine Receptor in Leukemias

Sergej Konoplev, MD, PhD, Hongbo Lu, MMSC, Michael A Fiegl, MD, Zhihong Zeng, PhD, Wenjing Chen, MD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2423.
https://doi.org/10.1182/blood.V112.11.2423.2423
Published: 2008