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Journal Articles

Mechanisms of Resistance and Determinants of Response of the GPRC5D-Targeting T-Cell Redirecting Bispecific Antibody JNJ-7564 in Multiple Myeloma

Christie P.M. Verkleij, MD, Marloes Broekmans, Amy Wong, Sonja Zweegman, MDPhD, Raluca Verona, PhD, Homer Adams, III, PhD, Tuna Mutis, MD PhD, Niels W.C.J. van de Donk, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-141187
Published: 2020
Journal Articles

Translational Approach of Using Ex Vivo Cytotoxicity and Early Clinical Data to Predict Teclistamab Efficacious Therapeutic Range in Multiple Myeloma Patients

Suzette Girgis, PhD BPharm, MS, Shun Xin Wang Lin, PhD, Kodandaram Pillarisetti, MSc, Arnob Banerjee, MD, Jenna D. Goldberg, MD, Shoba Shetty, PhD, Tara Stephenson, PhD, Brandi W. Hilder, PhD, Brett Hanna, Jennifer Smit, Homer Adams III, PhD, Yu-Nien (Tom) Sun, PhD, Jeffrey R. Infante, MD, Yusri A Elsayed, MD PhD, Amarnath Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-140565
Published: 2020
Journal Articles

High Dimensional Immune Profiling in Smoldering Multiple Myeloma Identifies Novel Organizing Features of the Tumor Microenvironment

Hearn Jay Cho, MD PhD, Deepak Perumal, PhD, Adeeb H Rahman, PhD, Seunghee Kim-Schultze, PhD, Jennifer Yesil, Daniel Auclair, Tineke Casneuf, PhD, Homer Adams, III, PhD, Samir Parekh, MD, Sacha Gnjatic, PhD, Nicolas Fernandez, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4384.
https://doi.org/10.1182/blood-2019-130554
Published: 2019
Journal Articles

Immunogenomic Exploration of the Acute Myeloid Leukemia Microenvironment Identifies Determinants of T-Cell Fitness

Lauren K. Brady, PhD, David Soong, PhD, Evan F. Lind, PhD, Yoko Kosaka, PhD, Adam J. Lamble, MD, Michael Schaffer, PhD, Brendan P. Hodkinson, PhD, Clare Lefave, PhD, Ted Laderas, PhD, Shannon K. McWeeney, PhD, Homer Adams, III, PhD, Yann Abraham, PhD, Pegah Safabakhsh, MS, Jeffrey W. Tyner, PhD, Brian J. Druker, MD, Fei Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2750.
https://doi.org/10.1182/blood-2018-99-118424
Published: 2018
Journal Articles

Updated Results from the Phase 2 Centaurus Study of Daratumumab (DARA) Monotherapy in Patients with Intermediate-Risk or High-Risk Smoldering Multiple Myeloma (SMM)

Ola Landgren, MD PhD, Michele Cavo, MD, Ajai Chari, MD, Yael C Cohen, MD, Andrew Spencer, MBBS, FRACP, FRCPA, DM, Peter M. Voorhees, MD, Jane Estell, FRACP, Irwindeep Sandhu, MDFRCPC, Matthew Jenner, Catherine Williams, Niels WCJ van de Donk, MD PhD, Meral Beksac, MD, Hartmut Goldschmidt, MD, Philippe Moreau, Steven Kuppens, Rajesh Bandekar, Tobias Neff, Annelore Cortoos, MD, Pamela L Clemens, PhD, Ming Qi, Homer Adams, III, PhD, Craig C Hofmeister, MDMPH
Journal: Blood
Blood (2018) 132 (Supplement 1): 1994.
https://doi.org/10.1182/blood-2018-99-113467
Published: 2018
Journal Articles

Proteomic Profiling Reveals Targetable Pathways in MGUS (SLAMF6, TNFRSF8, TIMP1, TRL2) That May Contribute to Disease Progression

Tineke Casneuf, Volha Tryputsen, Homer Adams, III, Andrew Lysaght, A. Kate Sasser, Robert A Kyle, MD, S. Vincent Rajkumar, MD, Shaji K Kumar, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3805.
https://doi.org/10.1182/blood.V130.Suppl_1.3805.3805
Published: 2017
Journal Articles

Daratumumab in Combination with Lenalidomide Plus Dexamethasone Results in Persistent Natural Killer (NK) Cells with a Distinct Phenotype and Expansion of Effector Memory T-Cells in Pollux, a Phase 3 Randomized Study

Niels WCJ Van De Donk, Homer Adams, III, Greet Vanhoof, Jakub Krejcik, MD, Koen Van der Borght, Tineke Casneuf, PhD, Tina Smets, Amy Axel, Yann Abraham, Hugo Ceulmans, Frederik Stevenaert, Saad Z Usmani, MD, Torben Plesner, MD, Sagar Lonial, MD, Berris van Kessel-Welmers, Henk M Lokhorst, Tuna Mutis, PhD, Nizar J. Bahlis, MD, Jordan Schecter, Christopher Chiu, Hervé Avet-Loiseau, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3124.
https://doi.org/10.1182/blood.V130.Suppl_1.3124.3124
Published: 2017
Journal Articles

Mass Cytometry As a Modality to Identify Candidates for Immune Checkpoint Inhibitor Therapy within Acute Myeloid Leukemia

Adam Lamble, MD, Yoko Kosaka, PhD, Fei Huang, A Kate Sasser, PhD, Homer Adams, III, PhD, Cristina E. Tognon, Ted Laderas, PhD, Shannon K. McWeeney, Marc M. Loriaux, Jeffrey W. Tyner, Brian J. Druker, MD, Evan F. Lind, PhD
Journal: Blood
Blood (2016) 128 (22): 2829.
https://doi.org/10.1182/blood.V128.22.2829.2829
Published: 2016
Journal Articles

Enhanced VISTA Expression in a Subset of Patients with Acute Myeloid Leukemia

Adam Lamble, MD, Yoko Kosaka, PhD, Fei Huang, A Kate Sasser, PhD, Homer Adams, III, PhD, Cristina E. Tognon, Ted Laderas, PhD, Shannon K. McWeeney, Marc M. Loriaux, Jeffrey W. Tyner, Brian J. Druker, MD, Evan F. Lind, PhD
Journal: Blood
Blood (2016) 128 (22): 4056.
https://doi.org/10.1182/blood.V128.22.4056.4056
Published: 2016
Journal Articles

High-Parameter Mass Cytometry (CyTOF) Evaluation of Relapsed/Refractory Multiple Myeloma (MM) Pts (Pts) Treated with Daratumumab Supports Immune Modulation As a Novel Mechanism of Action

Homer Adams, III, PhD, Frederik Stevenaert, Jakub Krejcik, Koen Van der Borght, Tineke Casneuf, Tina Smets, Jaime Bald, Yann Abraham, Hugo Ceulemans, Greet Vanhoof, Tahamtan Ahmadi, MD, Saad Z Usmani, MD, Torben Plesner, Professor, Sagar Lonial, MD FACP, Berris van Kessel-Welmers, Henk M. Lokhorst, MD PhD, Tuna Mutis, MD PhD, Niels W.C.J. van de Donk, MD PhD, A. Kate Sasser
Journal: Blood
Blood (2016) 128 (22): 4521.
https://doi.org/10.1182/blood.V128.22.4521.4521
Published: 2016