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Heng-Huan Lee
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Journal Articles

Novel Insights into SOX11 Modulation of BCR Signaling and Targeting of BTK Resistance

Rudra Prasad Dutta, Heng-Huan Lee, Ravi Prakash Shukla, Violetta V Leshchenko, Fanye Meng, Fangfang Yan, Yang Liu, Husnu Kaniskan, Jian Jin, Lapo Alinari, Michael Wang, Samir Parekh
Journal: Blood
Blood (2024) 144 (Supplement 1): 1402.
https://doi.org/10.1182/blood-2024-210591
Published: 2024
Journal Articles

The Reversible BTK Inhibitor Nemtabrutinib Demonstrates Favorable Antitumor Efficacy and Enhances the Function of CAR T Cells in Mantle Cell Lymphoma

Margaret Elizabeth Simmons, Joseph McIntosh, Tianci Zhang, Yijing Li, Fangfang Yan, Yixin Yao, Lei Nie, Heng-Huan Lee, Wei Wang, Vivian Changying Jiang, Michael Wang, Yang Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 5789.
https://doi.org/10.1182/blood-2023-187405
Published: 2023
Journal Articles

Exploring BiTE-Integrated CAR T-Cell Therapy to Overcome Tumor Antigen Escape and Reinforce CAR-T Therapy in Mantle Cell Lymphoma

Grace Glass Crutchfield, Yang Liu, Fangfang Yan, Xiaolin Li, Heng-Huan Lee, Michael Wang, Yixin Yao
Journal: Blood
Blood (2023) 142 (Supplement 1): 6820.
https://doi.org/10.1182/blood-2023-190167
Published: 2023
Journal Articles

Establishment of a Patient-Derived Organoid Culture Platform for Mantle Cell Lymphoma Drug Sensitivity and CAR T Cell Anti-Tumor Activity Assay

Lei Nie, Yang Liu, Changying Jiang, Yuxuan Che, Jingling Jin, Qingsong Cai, Wei Wang, Yijing Li, Alexa A Jordan, Joseph McIntosh, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9219–9220.
https://doi.org/10.1182/blood-2022-169622
Published: 2022
Journal Articles

Modulating Immunometabolism to Reinvigorate T-Cell Effector Function and Antitumor Immunity in the Mantle Cell Lymphoma Microenvironment

Yixin Yao, Yang Liu, Yuxuan Che, Yijing Li, Heng-Huan Lee, Michael L. Wang, Joseph McIntosh
Journal: Blood
Blood (2022) 140 (Supplement 1): 6446–6447.
https://doi.org/10.1182/blood-2022-169543
Published: 2022
Journal Articles

HSP27 Promotes Mantle Cell Lymphoma Growth and Mediates Resistance to Venetoclax

Yuxuan Che, Wei Wang, Yang Liu, Heng-Huan Lee, Yijing Li, Zhihong Chen, Joseph McIntosh, Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 6405–6406.
https://doi.org/10.1182/blood-2022-167611
Published: 2022
Journal Articles

Targeting the HSP90-MYC-CDK9 Axis to Overcome Dual Resistance to BTK Inhibition and CAR-T Therapy in Mantle Cell Lymphoma

Vivian Changying Jiang, Fangfang Yan, Alexa A Jordan, Yuxuan Che, Yang Liu, Qingsong Cai, Yijing Li, Joseph McIntosh, Zhihong Chen, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Jingling Jin, Wei Wang, Lei Nie, Zhongming Zhao, Lukas M Simon, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3512–3513.
https://doi.org/10.1182/blood-2022-163696
Published: 2022
Journal Articles

Dasatinib Increases MHCII Surface Levels and Can Synergize with Anti-PD1 Therapy to Increase the Anti-Tumor Effect in a Pre-Clinical Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Model

Paul Koller, MD, Karine Harutyunyan, PhD, Antonio Cavazos, MSc, Natalia Baran, PhDMD, Saradhi Mallampati, DVM, PhD, Renee Chin, Zhou Jiang, PhD, Heng-Huan Lee, PhD, Michael Curran, PhD, Mien-Chie Hung, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44.
https://doi.org/10.1182/blood-2020-141654
Published: 2020