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Alexa A Jordan
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Journal Articles

Establishment of a Patient-Derived Organoid Culture Platform for Mantle Cell Lymphoma Drug Sensitivity and CAR T Cell Anti-Tumor Activity Assay

Lei Nie, Yang Liu, Changying Jiang, Yuxuan Che, Jingling Jin, Qingsong Cai, Wei Wang, Yijing Li, Alexa A Jordan, Joseph McIntosh, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9219–9220.
https://doi.org/10.1182/blood-2022-169622
Published: 2022
Journal Articles

Targeting the HSP90-MYC-CDK9 Axis to Overcome Dual Resistance to BTK Inhibition and CAR-T Therapy in Mantle Cell Lymphoma

Vivian Changying Jiang, Fangfang Yan, Alexa A Jordan, Yuxuan Che, Yang Liu, Qingsong Cai, Yijing Li, Joseph McIntosh, Zhihong Chen, Jovanny Vargas, Yixin Yao, Heng-Huan Lee, Jingling Jin, Wei Wang, Lei Nie, Zhongming Zhao, Lukas M Simon, Michael L. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3512–3513.
https://doi.org/10.1182/blood-2022-163696
Published: 2022
Journal Articles

Abemaciclib in Combination with Copanlisib to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Yuxuan Che, Yang Liu, Yijing Li, Joseph McIntosh, Alexa A Jordan, Zhihong Chen, Fangfang Yan, Wei Wang, Jingling Jin, Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2253.
https://doi.org/10.1182/blood-2021-150942
Published: 2021
Journal Articles

Establishment of Patient-Derived Organoid Culture Platform of Mantle Cell Lymphoma

Lei Nie, Yang Liu, Yuxuan Che, Yijing Li, Wei Wang, Jingling Jin, Qingsong Cai, Jovanny Vargas, Joseph McIntosh, Alexa A Jordan, Vivian Changying Jiang, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3508.
https://doi.org/10.1182/blood-2021-152994
Published: 2021
Journal Articles

Dynamic Reprogramming and Evolution Associated with Sequential Resistance to Ibrutinib and CAR T Therapy in Mantle Cell Lymphoma

Fangfang Yan, Changying Jiang, Qingsong Cai, Preetesh Jain, Yijing Li, Yang Liu, Joseph McIntosh, Alexa A Jordan, Zhongming Zhao, Lukas Simon, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2396.
https://doi.org/10.1182/blood-2021-149214
Published: 2021
Journal Articles

Single Cell Transcriptomic Profiling of Patient-Derived Xenografts of Mantle Cell Lymphoma Reveals a Special Tumor Cell Population: Seed Cells for Disease Dissemination and Progression

Vivian Changying Jiang, Qingsong Cai, Dapeng Hao, Yang Liu, Yijing Li, Yuxuan Che, Joseph McIntosh, Alexa A Jordan, Zhihong Chen, Angela Leeming, Lei Nie, Linghua Wang, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1319.
https://doi.org/10.1182/blood-2021-149280
Published: 2021
Journal Articles

Bispecific CD19-CD20 and CD19-CD22 CAR-T Cells with Glycogen Synthase Kinase (GSK)-3β Inhibitor TWS119 Treatment Have Superior Therapeutic Effects on Mantle Cell Lymphoma

Jingling Jin, Yijing Li, Yang Liu, Alexa A Jordan, Joseph McIntosh, Jovanny Vargas, Yuxuan Che, Yixin Yao, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1698.
https://doi.org/10.1182/blood-2021-150000
Published: 2021
Journal Articles

Combination Therapy of Bcl-2/X L dual Inhibitor AZD0466 with Acalabrutinib to Overcome Therapeutic Resistance in Aggressive R/R Mantle Cell Lymphoma

Yijing Li, Yang Liu, Yuxuan Che, Joseph McIntosh, Alexa A Jordan, Angela Leeming, Courtney L Andersen, Justin Cidado, Jingling Jin, Vivian Changying Jiang, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1867.
https://doi.org/10.1182/blood-2021-151609
Published: 2021
Journal Articles

Pirtobrutinib Overcomes Ibrutinib and Venetoclax Resistance in Mantle Cell Lymphoma

Yang Liu, Changying Jiang, Fangfang Yan, Joseph McIntosh, Alexa A Jordan, Yijing Li, Yuxuan Che, Qingsong Cai, Wei Wang, Lei Nie, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1182.
https://doi.org/10.1182/blood-2021-151401
Published: 2021
Journal Articles

Dual Targeting Bcl-2 By Venetoclax and Mcl-1 By AZD5991 to Overcome Therapeutic Resistance in Aggressive R/R Mantle Cell Lymphoma

Yijing Li, Yang Liu, Yuxuan Che, Alexa A Jordan, Joseph McIntosh, Angela Leeming, Courtney L Andersen, Justin Cidado, Jingling Jin, Vivian Changying Jiang, Michael Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1181.
https://doi.org/10.1182/blood-2021-151062
Published: 2021
Journal Articles

Interrogation of Dysregulated Pathways Enables Precision Medicine in Mantle Cell Lymphoma

Yang Liu, PhD, Shuangtao Zhao, PhD, Changying Changying Jiang, PhD, Yixin Yao, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Yijing Li, MS, Yuxuan Che, Preetesh Jain, MBBS,MDDM,PhD, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-140794
Published: 2020
Journal Articles

Abemaciclib-Based Combinational Therapies to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Yuxuan Che, Yang Liu, PhD, Lingzhi Li, Holly Hill, Joseph McIntosh, BS, Alexa A Jordan, BS, Dayoung Jung, Yixin Yao, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-140856
Published: 2020
Journal Articles

MCL Cells in Tumor Microenvironment Impair T-Cell Metabolic Fitness and Effector Function

Yixin Yao, PhD, Yuxuan Che, Yang Liu, PhD, Lingzhi Li, Alexa A Jordan, BS, Preetesh Jain, MBBS,MDDM,PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16.
https://doi.org/10.1182/blood-2020-139611
Published: 2020
Journal Articles

Targeting ROR1 Using the Antibody Drug Conjugate Vls-101 in Aggressive Mantle Cell Lymphoma

Vivian Changying Jiang, PhD, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Zhihong Chen, Katti A. Jessen, PhD, Brian J. Lannutti, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-137660
Published: 2020
Journal Articles

Targeting Antibody Checkpoint Fcgriib Using Monoclonal Antibody BI-1206 to Overcome Therapeutic Resistance in Mantle Cell Lymphoma

Alexa A Jordan, BS, Joseph McIntosh, BS, Yang Liu, PhD, Angela Leeming, William Lee, Ingrid Karlsson, PhD, Linda Mårtensson, PhD, Mathilda Kovacek, Ingrid Teige, PhD, Björn Frendéus, PhD, Michael Wang, MD, Changying Changying Jiang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-140849
Published: 2020
Journal Articles

Overcoming CAR T Resistance with Non-Covalent BTK Inhibitor Loxo-305 in Mantle Cell Lymphoma

Yang Liu, PhD, Vivian Changying Jiang, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Yijing Li, MS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-137645
Published: 2020
Journal Articles

Combination of Ibrutinib with Rituximab (IR) in Previously Untreated Older Patients with Mantle Cell Lymphoma (MCL) - a Phase II Clinical Trial

Preetesh Jain, MBBS,MDDM,PhD, Yixin Yao, PhD, Shuangtao Zhao, PhD, Yang Liu, PhD, Holly Hill, Yuxuan Che, Yijing Li, MS, Alexa A Jordan, BS, Joseph McIntosh, BS, Hun Ju Lee, MD, Raphael Eric Steiner, MD, Felipe Samaniego, MD, Jason Westin, MD, Loretta J. Nastoupil, MD, Ranjit Nair, Sairah Ahmed, MD, Chi Young Ok, MD, Rashmi Kanagal-Shamanna, MD, Onyeka Oriabure, Guofang Xu, MD, Wendy Chen, Omar Moghrabi, Chloe Marie McClain, Maria Badillo, MSN, RN, OCN, CCRP, Selvi Thirumurthi, David Santos, Cezar Iliescu, MD, C. Cameron Yin, MD PhD, Shaoying Li, MD, Guilin Tang, MD, Francisco Vega, MDPhD, Sattva S. Neelapu, MD, Christopher Flowers, MDMS, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-137167
Published: 2020
Journal Articles

AZD4320 Is a Novel and Potent BCL-2/X L Dual Inhibitor in Targeting Aggressive Mantle Cell Lymphoma

Yijing Li, MS, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Courtney L Andersen, PhD, Justin Cidado, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44.
https://doi.org/10.1182/blood-2020-140775
Published: 2020
Journal Articles

Targeting Transcription Checkpoint Using a Novel CDK9 Inhibitor in Mantle Cell Lymphoma

Junwei Lian, PhD, Yu Xue, PhD, Alexa A Jordan, BS, Joseph McIntosh, BS, Yang Liu, PhD, Michael Wang, MD, Jia Zhou, PhD, Vivian Changying Jiang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-140865
Published: 2020