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Heather A. Leitch
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Journal Articles

Impact of Frailty in a Prospective Cohort of Patients with MDS Treated with Hypomethylating Agents

James T England, Liying Zhang, Karen Yee, Michelle Geddes, Nancy Zhu, April Shamy, Heather A Leitch, Mitchell Sabloff, Grace Christou, Brett L. Houston, Brian Leber, Dina Khalaf, Eve St-Hilaire, Nicholas Finn, Thomas J. Nevill, Amy Trottier, John M. Storring, Mohamed Elemary, Robert Delage, Rena Buckstein
Journal: Blood
Blood (2024) 144 (Supplement 1): 4598.
https://doi.org/10.1182/blood-2024-211183
Published: 2024
Journal Articles

Improvement in Quality of Life in MDS Patients Who Become Transfusion Independent after Treatment

Bo Wan, Shabbir MH Alibhai, Lisa Chodirker, Lee Mozessohn, Michelle Geddes, Nancy Zhu, Amy Trottier, Eve St-Hilaire, Nicholas Finn, Brian Leber, Dina Khalaf, Grace Christou, Mitchell Sabloff, Heather A Leitch, April Shamy, Karen Yee, John M. Storring, Thomas J. Nevill, Brett L. Houston, Mohamed Elemary, Robert Delage, Anne Parmentier, Mohammad Siddiqui, Alexandre Mamedov, Liying Zhang, Rena Buckstein
Journal: Blood
Blood (2024) 144 (Supplement 1): 4583.
https://doi.org/10.1182/blood-2024-194441
Published: 2024
Journal Articles

How I treat iron overload in adult myelodysplastic syndrome

Heather A Leitch, Rena J. Buckstein
Journal: Blood
Blood blood.2023022501.
https://doi.org/10.1182/blood.2023022501
Published: 2024
Includes: Supplemental data
Journal Articles

Interactions between Iron Overload, Oxidative Stress, and Somatic Mutations in Myelodysplastic Syndromes; Evidence from the Literature

Wendy Marina Davis, Heather A Leitch
Journal: Blood
Blood (2023) 142 (Supplement 1): 6464.
https://doi.org/10.1182/blood-2023-173975
Published: 2023
Journal Articles

The Use of Novel Therapies Reduces the Risk of Autoimmune Complications in CLL: A Population-Based Study in British Columbia

Rayan Ramadan, Alaa Alzaki, Heather A. Leitch
Journal: Blood
Blood (2022) 140 (Supplement 1): 4148–4149.
https://doi.org/10.1182/blood-2022-168369
Published: 2022
Journal Articles

Phase 1 Study of JNJ-64619178, a Protein Arginine Methyltransferase 5 Inhibitor, in Patients with Lower-Risk Myelodysplastic Syndromes

Tamanna Haque, Felix López Cadenas, Blanca Xicoy, Ana Alfonso, Uwe Platzbecker, Irit Avivi, Andrew M. Brunner, Jörg Chromik, Daniel Morillo, Manish R. Patel, José F. Falantes, Heather A. Leitch, Ulrich Germing, Meir Preis, David Lavie, Laurie Lenox, Josh Lauring, Anna Kalota, Regina Brown, Jaydeep Mehta, Friederike Pastore, Pankaj Mistry, David Valcarcel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2606.
https://doi.org/10.1182/blood-2021-146987
Published: 2021
Journal Articles

Fatigue, However Measured, Continues to Refine Prognosis in Higher Risk MDS: An MDS-CAN Study

Irina Amitai, MD, Michelle Geddes, MD, Nancy Zhu, MD, Mary-Margaret Keating, MD FRCPC, Mitchell Sabloff, Grace Christou, MD, Brian Leber, MD, Dina Khalaf, BSc, MSc, MD, Heather A. Leitch, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, April Shamy, MD, Karen W.L. Yee, MD, John M. Storring, MD, Thomas J. Nevill, MD, Robert Delage, MD, Mohamed Elemary, MD, Versha Banerji, MD, Lisa Chodirker, MD, Lee Mozessohn, MD, Anne Parmentier, BA, Mohammed Siddiqui, Alexandre Mamedov, Liying Zhang, PhD, Rena J. Buckstein, MD FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–43.
https://doi.org/10.1182/blood-2020-141635
Published: 2020
Journal Articles

High Transfusion Dependence and Serum Ferritin but Not Transferrin Saturation Predict Inferior Clinical Outcomes in Patients with MDS

Jennifer Teichman, MD, Michelle Geddes, MD, Nancy Zhu, MD, Mary-Margaret Keating, MD FRCPC, Mitchell Sabloff, MSc,MDFRCPC, Grace Christou, MD, Brian Leber, MD, Dina Khalaf, BSc, MSc, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, April Shamy, MD, Karen W.L. Yee, MD, John M. Storring, MD, Thomas J. Nevill, MD, Robert Delage, MD, Mohamed Elemary, MD, Versha Banerji, MD, Lee Mozessohn, MD, Lisa Chodirker, MD, Liying Zhang, PhD, Mohammed Siddiqui, Anne Parmentier, BA, Heather A. Leitch, MD, Rena J. Buckstein, MD FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-140065
Published: 2020
Journal Articles

Intermittent Transfusion Independence Is Associated with Improved Overall Survival in Patients with Transfusion Dependent MDS

Rena Buckstein, MD FRCPC, Lisa Chodirker, MD, Michelle Geddes, MD, Nancy Zhu, MD, Grace Christou, MD, Mitchell Sabloff, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, Thomas J. Nevill, MD, John Storring, MD, April Shamy, MD, Versha Banerji, MD, Mohamed Elemary, MD, Robert Delage, MD, Alexandre Mamedov, Liying Zhang, PhD, Aksharh Kirubananthaan, Richard A. Wells, MD DPhil
Journal: Blood
Blood (2019) 134 (Supplement_1): 5416.
https://doi.org/10.1182/blood-2019-129464
Published: 2019
Journal Articles

Persistent Red Blood Cell (RBC) Transfusion Is Associated with Increased Mortality Risk in Transfusion-Dependent (TD) Patients with Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS+)

Rena Buckstein, MD FRCPC, Nancy Zhu, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Lisa Chodirker, MD, Mitchell Sabloff, Grace Cristou, Heather A. Leitch, MD, Eve St. Hilaire, Nicholas Finn, MD, Karen W.L. Yee, MD, Mohamed Elemary, MD, Versha Banerji, MD, Martha Lenis, Aksharh Kirubananthaan, Fei Fei Liu, Derek Tang, PhD BSPharm, Chris Westcott, Vicky Wei-Hsuen Huang, Di Wang, Chris Cameron, Jessica Morison, Paul Spin, Alexandre Mamedov
Journal: Blood
Blood (2019) 134 (Supplement_1): 3012.
https://doi.org/10.1182/blood-2019-123684
Published: 2019
Journal Articles

Prognostic Performance of Frailty Measures in MDS Patients Treated with Hypomethylating Agents

Bo Angela Wan, BA, MPhil, Richard A. Wells, MD DPhil, Lisa Chodirker, MD, Ken Rockwood, MD, Michelle Geddes, MD, Nancy Zhu, MD, Grace Christou, MD MSc, Mitchell Sabloff, MSc,MDFRCPC, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, John Storring, MD, Thomas J. Nevill, MD, April Shamy, MD, Versha Banerji, MD, Mohamed Elemary, MD, Robert Delage, MD, Alexandre Mamedov, Martha Lenis, Liying Zhang, PhD, Aksharh Kirubananthaan, Shabbir Alibhai, Rena Buckstein, MD FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 4245.
https://doi.org/10.1182/blood-2019-128949
Published: 2019
Journal Articles

Iron Overload in Patients Aged 60 Years and Older with Acute Myeloid Leukemia May Impact Adversely on Overall Survival

Colleen A. C. Wong, Chantal Leger, MD FRCPC, Heather A. Leitch, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3982.
https://doi.org/10.1182/blood-2018-99-112307
Published: 2018
Journal Articles

Health Related Quality of Life Remains Stable over Time in Myelodysplastic Syndrome: An MDS-CAN Prospective Study

Danielle N. Blunt, BMBS, Richard A. Wells, MD DPhil, Martha Lenis, Lisa Chodirker, MD, Michelle Geddes, MD, Nancy Zhu, MD, Jill Fulcher, MD PhD, Mitchell Sabloff, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas G. Finn, MD, April Shamy, MD, Mohamed Elemary, MD, Robert Delage, MD, Ken Rockwood, MD, Versha Banerji, MD, Alexandre Mamedov, Liying Zhang, PhD, Rena Buckstein, MD FRCPC
Journal: Blood
Blood (2018) 132 (Supplement 1): 4850.
https://doi.org/10.1182/blood-2018-99-114327
Published: 2018
Journal Articles

Iron Overload in Lower International Prognostic Scoring System Risk Myelodysplastic Syndromes Patients Receiving Red Blood Cell Transfusions: Relation to Infection and Possible Benefit of Iron Chelation Therapy

Colleen A. C. Wong, Shannon A. Y. Wong, Heather A. Leitch, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2986.
https://doi.org/10.1182/blood.V130.Suppl_1.2986.2986
Published: 2017
Journal Articles

An MDS Specific Frailty Index Based on Cumulative Deficits Adds Independent Prognostic Value to Established Clinical Prognostic Scoring Systems

Rebecca Starkman, Richard A. Wells, MD DPhil, Lisa Chodirker, MD, Ken Rockwood, MD, Michelle Geddes, MD, Nancy Zhu, MD, Jill Fulcher, MD PhD, Mitchell Sabloff, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas G. Finn, MD, John Storring, MD, Thomas J Nevill, MD, April Shamy, MD, Rajat Kumar, MD, Mohamed Elemary, MD, Robert Delage, MD, Martha Lenis, Alexandre Mamedov, Liying Zhang, PhD, Rena Buckstein, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1686.
https://doi.org/10.1182/blood.V130.Suppl_1.1686.1686
Published: 2017
Journal Articles

Predictive Factors of Overall Survival and the Completion of Four Cycles of Azacitidine: An MDS-CAN Study

Danielle N. Blunt, BMBS, Richard A. Wells, MD DPhil, Lisa Chodirker, MD, Ken Rockwood, MD, Michelle Geddes, MD, Nancy Zhu, MD, Jill Fulcher, MD PhD, Mitchell Sabloff, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas G. Finn, MD, John Storring, MD, Thomas J. Nevill, MD, April Shamy, MD, Rajat Kumar, MD, Mohamed Elemary, MD, Robert Delage, MD, Martha Lenis, Alexandre Mamedov, Liying Zhang, PhD, Rena Buckstein, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4253.
https://doi.org/10.1182/blood.V130.Suppl_1.4253.4253
Published: 2017
Journal Articles

Iron Chelation Is Associated with Improved Survival Adjusting for Disease and Patient Related Characteristics in Low/Int-1 Risk MDS at the Time of First Transfusion Dependence: A MDS-CAN Study

Ambica Parmar, MD, Heather A Leitch, MD PhD, Richard A. Wells, MD DPhil, Thomas J. Nevill, MD FRCPC, Nancy Y Zhu, MDFRCPC, Karen W.L. Yee, MD, Brian Leber, MD, Mitchell Sabloff, MDM, Eve St-Hilaire, MD, Rajat Kumar, MD, Michelle Geddes, MD FRCPC, John Storring, MD, Andrea Kew, MD, April Shamy, MDM, Mohamed Elemary, MD MSc,PhD, Martha Lenis, Alex Mamedov, Rena Buckstein, MD FRCPC
Journal: Blood
Blood (2015) 126 (23): 1701.
https://doi.org/10.1182/blood.V126.23.1701.1701
Published: 2015
Journal Articles

Patient Related Factors Have an Indepedent Impact on Overall Survival in Myelodysplastic Syndrome Patients: A Report of the MDS-Can Registry

Rena Buckstein, MD, Richard A. Wells, MD DPhil, Nancy Zhu, MD, Thomas J. Nevill, MD, Heather A Leitch, MD PhD, Karen W.L. Yee, MD, Brian Leber, MD, Mitchell Sabloff, MDM, Rajat Kumar, MD, Michelle Geddes, MD, April Shamy, MDM, Max Levitt, Martha Lenis, Alex Mamedov, Liying Zhang, PhD, Shabbir MH Alibhai, MD
Journal: Blood
Blood (2014) 124 (21): 165.
https://doi.org/10.1182/blood.V124.21.165.165
Published: 2014
Journal Articles

Autoimmune Cytopenia in Chronic Lymphocytic Leukemia: Effect on Outcome and Survival, a Population Based Analysis in British Columbia, Canada

Alaa A Alzaki, MBBS, Alina S Gerrie, MD, Tanya L. Gillan, PhD FCCMG, Steven Huang, Miriam Ahmed, Cynthia L. Toze, MD FRCPC, Heather A Leitch, MD PhD, Khaled M Ramadan, MB
Journal: Blood
Blood (2014) 124 (21): 1945.
https://doi.org/10.1182/blood.V124.21.1945.1945
Published: 2014
Journal Articles

Association Between Increased Liver Iron Concentration and Vitamin D Deficiency in Patients with Transfusion Dependent Hemoglobinopathies in British Columbia

Hatoon Ezzat, MBBS, FRCP, ABIM, John K. Wu, MBBS, FRCPC, Heather McCartney, Heather A Leitch, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3203.
https://doi.org/10.1182/blood.V120.21.3203.3203
Published: 2012