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Hans Bitter, PhD
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Journal Articles

Idecabtagene Vicleucel (ide-cel, bb2121) Responses Are Characterized By Early and Temporally Consistent Activation and Expansion of CAR T Cells with a T Effector Phenotype

Nathan Martin, PhD, Ethan G. Thompson, PhD, Will Brown, MS, Olivia Finney, PhD, Julie Rytlewski, PhD, Yue Jiang, PhD, Dipen Sangurdekar, PhD, Julie Wang, PharmD, PhD, Hans Bitter, PhD, Ronald J. Hause, Jr., PhD, Timothy B. Campbell, MD PhD, Kristen Hege, MD, Shari Kaiser, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-134378
Published: 2020
Journal Articles

Updated Results from the Phase I CRB-402 Study of Anti-Bcma CAR-T Cell Therapy bb21217 in Patients with Relapsed and Refractory Multiple Myeloma: Correlation of Expansion and Duration of Response with T Cell Phenotypes

Melissa Alsina, MD, Nina Shah, MD, Noopur S. Raje, MD, Sundar Jagannath, MD, Deepu Madduri, MD, Jonathan L. Kaufman, MD, David S. Siegel, MD PhD, Nikhil C. Munshi, MD, Jacalyn Rosenblatt, MD, Yi Lin, MD PhD, Andrzej Jakubowiak, MD PhD, Jagoda Jasielec, MD, Alison Timm, MS, Ashley Turka, Pingping Mao, PhD, Nathan Martin, PhD, Timothy B. Campbell, MD PhD, Kristen Hege, Hans Bitter, PhD, Fabio Petrocca, MD, Jesus G. Berdeja, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-140410
Published: 2020
Journal Articles

Molecular and Phenotypic Profiling of Drug Product and Post-Infusion Samples from CRB-402, an Ongoing: Phase I Clinical Study of bb21217 a BCMA-Directed CAR T Cell Therapy

Olivia C Finney, Ashish Yeri, PhD, Pingping Mao, PhD, Chetanya Pandya, PhD, Eric Alonzo, PhD, Gregory Hopkins, BS, Sebastian Hymson, BS, Tiffany Hu, BS, Marianna Foos, MS, Sneha Bhadoriya, MS, Stephanie Hintzen, BS, Maple Gioia, MS, Alison Timm, MS, Monica Massaro, MPH, Ron Hause, PhD, Shari Kaiser, PhD, Nathan Martin, PhD, Melissa Alsina, MD, Nina Shah, MD, Noopur S. Raje, MD, Jesus G. Berdeja, MD, Shannon Grande, PhD, Hans Bitter, PhD, Fabio Petrocca, MD, Kevin M. Friedman, PhD, Dipen Sangurdekar, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-142426
Published: 2020
Journal Articles

Effects of Prior Alkylating Therapies on Preinfusion Patient Characteristics and Starting Material for CAR T Cell Product Manufacturing in Late-Line Multiple Myeloma

Julie Rytlewski, PhD, Deepu Madduri, MD, Jaymes Fuller, PhD, Timothy B. Campbell, MD PhD, Afshin Mashadi-Hossein, MSc, Ethan G. Thompson, PhD, Yue Jiang, PhD, Nathan Martin, PhD, Dipen Sangurdekar, PhD, Olivia Finney, PhD, Hans Bitter, PhD, Amit Agarwal, MD PhD, Shari Kaiser, PhD, Kristen Hege, MD, Ronald J. Hause, Jr., PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-134369
Published: 2020
Journal Articles

Identification of Functional Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy of Chronic Lymphocytic Leukemia

Joseph A Fraietta, PhD, Simon F Lacey, PhD BS, Elena Orlando, PhD, Julian Pruteanu, PhD, Mercy Gohil, Yan Wang, PhD, Alina Boesteanu, PhD, Roddy OConnor, PhD, David E Ambrose, BS, Wei-Ting Hwang, PhD, Nicholas Wilcox, Felipe Bedoya, PhD, Corin Dorfmeier, Fang Chen, PhD, Harit Parakandi, Minnal Gupta, Edward Pequignot, MS, F. Brad Johnson, PhD, Irina Kulikovskaya, Li Liu, Stefan M Lundh, BS, Jun Xu, PhD, Megan M Davis, PhD, Regina M Young, PhD, Bruce L Levine, PhD, Don L. Siegel, MD PhD, Alexander Huang, PhD, E. John Wherry, PhD, Jing Zhou, Patrick Paczkowski, Sean Mackay, Jennifer Brogdon, PhD, Hans Bitter, PhD, David L Porter, MD, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3181.
https://doi.org/10.1182/blood.V130.Suppl_1.3181.3181
Published: 2017
Journal Articles

Biomarkers of Response to Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy in Patients with Chronic Lymphocytic Leukemia

Joseph A. Fraietta, PhD, Simon F. Lacey, PhD, Nicholas S Wilcox, Felipe Bedoya, PhD, Fang Chen, PhD, Elena Orlando, PhD, Jennifer L Brogdon, PhD, Wei-Ting Hwang, PhD, Noelle Frey, MD MS, Regina M Young, PhD, Edward Pequignot, M.S., David E Ambrose, BS, Bruce L Levine, PhD, Hans Bitter, PhD, David L Porter, MD, Jun Xu, PhD, Carl H June, MD, Jan Joseph Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 57.
https://doi.org/10.1182/blood.V128.22.57.57
Published: 2016