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Journal Articles

Identification of a Spontaneous Noncoding Mutation on Chromosome 18 Which Suppresses Thrombosis in Factor V Leiden Homozygous, TFPI Deficient Mice

Marisa A Brake, BSc, McKenzie A Allen, BSc, Guojing Zhu, MD, Amy E Siebert, PhD, Randal J Westrick, PhD

Blood (2019) 134 (Supplement_1): 483.

https://doi.org/10.1182/blood-2019-130936

Published: 2019

Journal Articles

Effects of Actr2 gene Variants on Mouse Viability, Gene Expression, and Cytoskeletal Dynamics

Linzi M Hobbs, BS, Amy E Siebert, PhD, Alexander J Johnston, BS, Marisa A Brake, BSc, Vakharia Paras, PharmD, MD, Cleuren Audrey, PhD, Guojing Zhu, MD, Randal J Westrick, PhD

Blood (2019) 134 (Supplement_1): 2340.

https://doi.org/10.1182/blood-2019-131004

Published: 2019

Journal Articles

A Missense Mutation in the Loss-of-Function Intolerant Actr2 Gene Suppresses Thrombosis Via Multiple Mechanisms

Amy E Siebert, MS, Linzi M Hobbs, Alexander J Johnston, Lena M Mishack, Marisa A Brake, BS, Audrey Cleuren, PhD, Guojing Zhu, MD, Randal Joseph Westrick, PhD

Blood (2017) 130 (Supplement 1): 1058.

https://doi.org/10.1182/blood.V130.Suppl_1.1058.1058

Published: 2017

Journal Articles

Overlap of SEC23A and SEC23B Function Suggests a Novel Therapeutic Approach for Congenital Dyserythropoietic Anemia Type II

Rami Khoriaty, MD, Angela Weyand, MD, Geoffrey Hesketh, PhD, Amélie Bernard, PhD, Lesley Everett, MD PhD, Guojing Zhu, MD, Beth McGee, Bin Zhang, PhD, Daniel Klionsky, PhD, Anne-Claude Gingras, Jordan A. Shavit, MD PhD, David Ginsburg, MD

Blood (2017) 130 (Supplement 1): 80.

https://doi.org/10.1182/blood.V130.Suppl_1.80.80

Published: 2017

Journal Articles

Mice with LMAN1 Deficiency Exhibit Thrombocytopenia and Reduced Serum Thrombopoietin Level

Rami Khoriaty, MD, Lesley Everett, BS, MPhil, Jennifer Chase, Guojing Zhu, Bin Zhang, PhD, Ivan Maillard, MD PhD, David Ginsburg, MD

Blood (2016) 128 (22): 412.

https://doi.org/10.1182/blood.V128.22.412.412

Published: 2016

Journal Articles

SEC23A Functionally Compensates for SEC23B Deficiency in Mice

Rami Khoriaty, MD, Lesley Everett, BS, MPhil, Jennifer Chase, Guojing Zhu, Bin Zhang, PhD, Mark Hoenerhoff, DVM, PhD DACVP, Ivan Maillard, MD PhD, David Ginsburg, MD

Blood (2015) 126 (23): 935.

https://doi.org/10.1182/blood.V126.23.935.935

Published: 2015

Journal Articles

A Sensitized Whole Genome ENU Mutagenesis Screen Identifies an Arp2 Missense Mutation As a Novel Suppressor of Lethal Thrombosis in the Factor V Leiden Mouse

Randal Joseph Westrick, PhD, Guojing Zhu, MD, Kart Tomberg, MS, David R. Siemieniak, BS, Sara A. Haynes, Jishu Xu, MS, Jun Z. Li, PhD, David Ginsburg, MD

Blood (2012) 120 (21): 493.

https://doi.org/10.1182/blood.V120.21.493.493

Published: 2012

Journal Articles

Whole-Exome Sequencing to Identify Mutations in Thrombosis Modifier Genes Isolated From a Factor V Leiden-Dependent Sensitized ENU Suppressor Screen in the Mouse

Randal Joseph Westrick, PhD, Guojing Zhu, MD, Jishu Xu, MS, Audrey C.A. Cleuren, PhD, Angela Yang, MS, David R Siemieniak, BS, Kart Tomberg, MS, Weiping Peng, BS, Jun Z Li, PhD, David Ginsburg, MD

Blood (2011) 118 (21): 1183.

https://doi.org/10.1182/blood.V118.21.1183.1183

Published: 2011

Journal Articles

The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis

Anil K. Chauhan, Meghan T. Walsh, Guojing Zhu, David Ginsburg, Denisa D. Wagner, David G. Motto

Blood (2008) 111 (7): 3452–3457.

https://doi.org/10.1182/blood-2007-08-108571

Published: 2008

Journal Articles

A Threshold Level of Von Willebrand Factor Is Required for Disease Pathogenesis in a Mouse Model of TTP.

David G. Motto, MD, PhD, Guojing Zhu, Denisa D. Wagner, PhD, David Ginsburg, MD

Blood (2006) 108 (11): 177.

https://doi.org/10.1182/blood.V108.11.177.177

Published: 2006

Journal Articles

Shigatoxin Triggers Thrombotic Thrombocytopenic Purpura in Genetically Susceptible ADAMTS13-Deficient Mice.

David G. Motto, MD, PhD, Anil K. Chauhan, PhD, Guojing Zhu, Jonathon Homeister, MD, PhD, Colin B. Lamb, Karl C. Desch, MD, Han-Mou Tsai, MD, Denisa D. Wagner, PhD, David Ginsburg, MD

Blood (2005) 106 (11): 723.

https://doi.org/10.1182/blood.V106.11.723.723

Published: 2005

Journal Articles

Additional Environmental and/or Genetic Factors Are Required to Trigger TTP in ADAMTS13-Deficient Mice.

David Motto, MD, PhD, Weirui Zhang, Guojing Zhu, Jonathon Homeister, MD, PhD, Han-Mou Tsai, MD, David Ginsburg, MD

Blood (2004) 104 (11): 258.

https://doi.org/10.1182/blood.V104.11.258.258

Published: 2004

NARROW

Identification of a Spontaneous Noncoding Mutation on Chromosome 18 Which Suppresses Thrombosis in Factor V Leiden Homozygous, TFPI Deficient Mice

Effects of Actr2 gene Variants on Mouse Viability, Gene Expression, and Cytoskeletal Dynamics

A Missense Mutation in the Loss-of-Function Intolerant Actr2 Gene Suppresses Thrombosis Via Multiple Mechanisms

Overlap of SEC23A and SEC23B Function Suggests a Novel Therapeutic Approach for Congenital Dyserythropoietic Anemia Type II

Mice with LMAN1 Deficiency Exhibit Thrombocytopenia and Reduced Serum Thrombopoietin Level

SEC23A Functionally Compensates for SEC23B Deficiency in Mice

A Sensitized Whole Genome ENU Mutagenesis Screen Identifies an Arp2 Missense Mutation As a Novel Suppressor of Lethal Thrombosis in the Factor V Leiden Mouse

Whole-Exome Sequencing to Identify Mutations in Thrombosis Modifier Genes Isolated From a Factor V Leiden-Dependent Sensitized ENU Suppressor Screen in the Mouse

The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis

A Threshold Level of Von Willebrand Factor Is Required for Disease Pathogenesis in a Mouse Model of TTP.

Shigatoxin Triggers Thrombotic Thrombocytopenic Purpura in Genetically Susceptible ADAMTS13-Deficient Mice.

Additional Environmental and/or Genetic Factors Are Required to Trigger TTP in ADAMTS13-Deficient Mice.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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