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David G. Motto
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Journal Articles

Diagnostic approach to von Willebrand disease

Clinical Trials & Observations
Christopher Ng, David G. Motto, Jorge Di Paola
Journal: Blood
Blood (2015) 125 (13): 2029–2037.
https://doi.org/10.1182/blood-2014-08-528398
Published: 2015
Journal Articles

Assessment Of Endothelial Damage and Cardiac Injury In a Mouse Model Mimicking Thrombotic Thrombocytopenic Purpura

Maelle Le Besnerais, Julie Favre, PhD, Cecile V. Denis, PhD, Bernard Lenormand, Paul Mulder, PhD, Lionel Nicol, PhD, Agnes Veyradier, MD PhD, Alexandra Schiviz, DVM, David G Motto, MD, PhD, Herve Levesque, MD PhD, Paul Coppo, MD PhD, Vincent Richard, PhD, Ygal Benhamou, MD
Journal: Blood
Blood (2013) 122 (21): 447.
https://doi.org/10.1182/blood.V122.21.447.447
Published: 2013
Journal Articles

Red blood cells mediate the onset of thrombosis in the ferric chloride murine model

Justin D. Barr, Anil K. Chauhan, Gilbert V. Schaeffer, Jessica K. Hansen, David G. Motto
Journal: Blood
Blood (2013) 121 (18): 3733–3741.
https://doi.org/10.1182/blood-2012-11-468983
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

ADAMTS13 deficiency exacerbates VWF-dependent acute myocardial ischemia/reperfusion injury in mice

Chintan Gandhi, David G. Motto, Melissa Jensen, Steven R. Lentz, Anil K. Chauhan
Journal: Blood
Blood (2012) 120 (26): 5224–5230.
https://doi.org/10.1182/blood-2012-06-440255
Published: 2012
Includes: Supplemental data
Journal Articles

ADAMTS13 Deficiency Exacerbates VWF-Dependent Acute Myocardial Ischemia/Reperfusion Injury in Mice

Chintan Gandhi, PhD, David G Motto, MD, PhD, Melissa Jensen, Steven R. Lentz, MD, PhD, Anil K Chauhan, PhD
Journal: Blood
Blood (2012) 120 (21): 264.
https://doi.org/10.1182/blood.V120.21.264.264
Published: 2012
Journal Articles

Endothelial Injury and Thrombus Formation In the Ferric Chloride Murine Model of Hemostasis

Justin Barr, Anil Chauhan, PhD, David G Motto, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 650.
https://doi.org/10.1182/blood.V116.21.650.650
Published: 2010
Journal Articles

EDA-Containing Fibronectin Aggravates Ischemic Brain Injury In Mice

Anil Chauhan, PhD, Mohammad M Khan, Ph.D, Chintan Gandhi, Ph.D, Neelam Chauhan, Ph.D, Asgar Zaheer, Ph.D, David G Motto, MD, PhD, Steven R. Lentz
Journal: Blood
Blood (2010) 116 (21): 330.
https://doi.org/10.1182/blood.V116.21.330.330
Published: 2010
Journal Articles

Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice

Jing Huang, David G. Motto, David R. Bundle, J. Evan Sadler
Journal: Blood
Blood (2010) 116 (18): 3653–3659.
https://doi.org/10.1182/blood-2010-02-271957
Published: 2010
Includes: Supplemental data
Journal Articles

The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis

Anil K. Chauhan, Meghan T. Walsh, Guojing Zhu, David Ginsburg, Denisa D. Wagner, David G. Motto
Journal: Blood
Blood (2008) 111 (7): 3452–3457.
https://doi.org/10.1182/blood-2007-08-108571
Published: 2008
Journal Articles

Phenotypic Correction of Adamts13 -Deficient Mice by Early Intra-Amniotic Gene Transfer of Lentiviral Vector Encoding ADAMTS13 Genes.

Masami Niiya, MD, PhD, Masayuki Endo, MD/PhD, Philip W. Zoltick, MD, Nidal E. Muvarak, David G. Motto, MD/PhD, Alan W. Flake, MD, X. Long Zheng, MD/PhD
Journal: Blood
Blood (2007) 110 (11): 197.
https://doi.org/10.1182/blood.V110.11.197.197
Published: 2007
Journal Articles

A Threshold Level of Von Willebrand Factor Is Required for Disease Pathogenesis in a Mouse Model of TTP.

David G. Motto, MD, PhD, Guojing Zhu, Denisa D. Wagner, PhD, David Ginsburg, MD
Journal: Blood
Blood (2006) 108 (11): 177.
https://doi.org/10.1182/blood.V108.11.177.177
Published: 2006
Journal Articles

Recombinant ADAMTS13 Processing by FXIa Is Distinct from Thrombin.

Enriqueta R. Guinto, PhD, Nicholas Grafos, BS, David G. Motto, MD, Robert S. Greenfield, Ph.D
Journal: Blood
Blood (2006) 108 (11): 4041.
https://doi.org/10.1182/blood.V108.11.4041.4041
Published: 2006
Journal Articles

Shigatoxin Triggers Thrombotic Thrombocytopenic Purpura in Genetically Susceptible ADAMTS13-Deficient Mice.

David G. Motto, MD, PhD, Anil K. Chauhan, PhD, Guojing Zhu, Jonathon Homeister, MD, PhD, Colin B. Lamb, Karl C. Desch, MD, Han-Mou Tsai, MD, Denisa D. Wagner, PhD, David Ginsburg, MD
Journal: Blood
Blood (2005) 106 (11): 723.
https://doi.org/10.1182/blood.V106.11.723.723
Published: 2005
Journal Articles

The Metalloprotease ADAMTS13 Is a Natural Anti-Thrombotic.

Anil K. Chauhan, PhD, David G. Motto, M.D, Ph.D, Colin B. Lamb, BS, Michael Dockal, Ph.D, Friedrich Scheiflinger, Ph.D, David Ginsburg, M.D, Ph.D, Denisa D. Wagner, Ph.D
Journal: Blood
Blood (2005) 106 (11): 409.
https://doi.org/10.1182/blood.V106.11.409.409
Published: 2005
Journal Articles

ADAMTS13 turns 3

Clinical Trials & Observations
Gallia G. Levy, David G. Motto, David Ginsburg
Journal: Blood
Blood (2005) 106 (1): 11–17.
https://doi.org/10.1182/blood-2004-10-4097
Published: 2005
Journal Articles

ADAMTS-13, VWF, inflammation, and thrombosis

David G. Motto
Journal: Blood
Blood (2004) 104 (1): 4–5.
https://doi.org/10.1182/blood-2004-04-1438
Published: 2004