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Journal Articles

Initial Report of Part B Phase 1/2 Efficacy and Safety Results for Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed Immune Thrombocytopenia

Nichola Cooper, A.J. Gerard Jansen, Robert Bird, Jiří Mayer, Michelle Sholzberg, Michael D. Tarantino, Mamta Garg, Paula F Ypma, Vickie McDonald, Charles Percy, Milan Košťál, Isaac Goncalves, Lachezar H. Bogdanov, Terry B Gernsheimer, Remco Diab, Mengjie Yao, Ahmed Daak, David J Kuter
Journal: Blood
Blood (2023) 142 (Supplement 1): 685.
https://doi.org/10.1182/blood-2023-177808
Published: 2023
Journal Articles

The Effects of Rilzabrutinib, an Oral Bruton Tyrosine Kinase Inhibitor, on Bleeding Symptoms and Health-Related Quality of Life in Patients with Immune Thrombocytopenia

Michael D. Tarantino, A.J. Gerard Jansen, Nichola Cooper, Imene Gouia, Mengjie Yao, Ahmed Daak, David J Kuter
Journal: Blood
Blood (2023) 142 (Supplement 1): 690.
https://doi.org/10.1182/blood-2023-177811
Published: 2023
Journal Articles

Safety and Efficacy of SARS-CoV-2 Vaccination in Patients with Immune Thrombocytopaenia: a Multi-Centre Review

Sara Stefani, Rocel C. Saputil, Michelle MH Tan, Noora Buti, Deena Paul, Naghma Rizvi, Vashti Ragoonanan, Emma Thorley, Ariam Teklemichael, Camelia Vladescu, Amna Malik, Christine Ademokun, Alice C J Hart, Richard Szydlo, George Adams, James B. Bussel, A.J. Gerard Jansen, Nichola Cooper
Journal: Blood
Blood (2022) 140 (Supplement 1): 5546–5548.
https://doi.org/10.1182/blood-2022-167614
Published: 2022
Journal Articles

Predicting Platelet Age Using Artificial Intelligence Techniques

Johan Slotman, Maurice Swinkels, Petra E. Burgisser, Joyce Bestebroer, Thomas R.L. Klei, Adriaan B. Houtsmuller, Frank W.G. Leebeek, Ruben Bierings, A.J. Gerard Jansen
Journal: Blood
Blood (2022) 140 (Supplement 1): 2656–2657.
https://doi.org/10.1182/blood-2022-159033
Published: 2022
Journal Articles

Updated Phase I/II Safety and Efficacy Results for Oral Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed/Refractory Immune Thrombocytopenia

David J. Kuter, Nikolay Tzvetkov, Merlin Efraim, Zane Kaplan, Jiří Mayer, Philip Choi, A.J. Gerard Jansen, Vickie McDonald, Ross Baker, Robert J. Bird, Mamta Garg, Jaromir Gumulec, Milan Kostal, Terry Gernsheimer, Waleed Ghanima, Olga Bandman, Puneet Arora, Regan Burns, Mengjie Yao, Ahmed Daak, Timothee Sourdille, Fareha Iqbal, Dolca Thomas, Ann Neale, Nichola Cooper
Journal: Blood
Blood (2021) 138 (Supplement 1): 14.
https://doi.org/10.1182/blood-2021-145128
Published: 2021
Journal Articles

The Effect of COVID-19 Vaccine in Patients with Immune Thrombocytopenia

Chantal Visser, Maurice Swinkels, Erik D. van Werkhoven, F. Nanne Croles, Heike Noordzij, Matthijs Eefting, Suzanne M. Last-Koopmans, Cecile Idink, Peter E. Westerweel, Bart Santbergen, Pieter A. Jobse, Fazil Baboe, Recovac-IR Consortium, Mark-David Levin, Marieke J.H.A. Kruip, A.J. Gerard Jansen
Journal: Blood
Blood (2021) 138 (Supplement 1): 587.
https://doi.org/10.1182/blood-2021-146529
Published: 2021
Journal Articles

Super-Resolution Immunofluorescence Imaging of Platelet Granules

Maurice Swinkels, MSc, BSc, Johan A. Slotman, PhD, Frank W.G. Leebeek, MD PhD, Jan Voorberg, PhD, Ruben Bierings, PhD, Gerard Jansen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3613.
https://doi.org/10.1182/blood-2019-124353
Published: 2019
Journal Articles

Uptake of Influenza Virus By Platelets Occurs Via Phagocytosis

Gerard Jansen, MD PhD, Huizhi Low, PhD, Judith van den Brand, DVM, PhD, Debbie van Riel, PhD, Erhard van der Vries, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4834.
https://doi.org/10.1182/blood.V130.Suppl_1.4834.4834
Published: 2017
Journal Articles

Platelets Can Phagocytose Influenza Virus Which May Contribute to the Occurrence of Thrombocytopenia during Influenza Infection

A.J. Gerard Jansen, MD PhD, Hui Zhi Low, PhD, Judith van den Brand, PhD, Debbie van Riel, PhD, Albert Osterhaus, PhD, Erhard van der Vries, PhD
Journal: Blood
Blood (2016) 128 (22): 1358.
https://doi.org/10.1182/blood.V128.22.1358.1358
Published: 2016
Journal Articles

Sialic Acid Loss Regulates Platelet Survival and Integrity

Renata Grozovsky, PhD, Gerard Jansen, MD, PhD, MSC, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2013) 122 (21): 3504.
https://doi.org/10.1182/blood.V122.21.3504.3504
Published: 2013
Journal Articles

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice

A. J. Gerard Jansen, Emma C. Josefsson, Viktoria Rumjantseva, Qiyong Peter Liu, Hervé Falet, Wolfgang Bergmeier, Stephen M. Cifuni, Robert Sackstein, Ulrich H. von Andrian, Denisa D. Wagner, John H. Hartwig, Karin M. Hoffmeister
Journal: Blood
Blood (2012) 119 (5): 1263–1273.
https://doi.org/10.1182/blood-2011-05-355628
Published: 2012
Includes: Supplemental data
Journal Articles

Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets

Gerard Jansen, MD, PhD, MSC, Emma C Josefsson, PhD, Qiyong Peter Liu, PhD, Viktoria Rumjantseva, PhD, Herve Falet, PhD, Renata Grozovsky, PhD, Wolfgang Bergmeier, PhD, Denisa D. Wagner, PhD, John H. Hartwig, PhD, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2011) 118 (21): 1133.
https://doi.org/10.1182/blood.V118.21.1133.1133
Published: 2011
Journal Articles

The Hepatic Asialoglycoprotein Receptor Regulates Platelet Homeostasis

Renata Grozovsky, Gerard Jansen, MD, PhD, MSC, Karin M. Hoffmeister, MD
Journal: Blood
Blood (2010) 116 (21): 2025.
https://doi.org/10.1182/blood.V116.21.2025.2025
Published: 2010
Journal Articles

Surface Sialic Acid Prevents Loss of GPIbα during Platelet Storage and Rescues In Vivo Survival of Murine Platelets.

Gerard Jansen, Emma C. Josefsson, John H. Hartwig, Karin M. Hoffmeister
Journal: Blood
Blood (2007) 110 (11): 138.
https://doi.org/10.1182/blood.V110.11.138.138
Published: 2007