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Gavin Macbeath
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Journal Articles

Initial Results of a Phase 1 Trial of TSC-100 and TSC-101, Engineered T Cell Therapies That Target Minor Histocompatibility Antigens to Prevent Relapse after Allogeneic Hematopoietic Cell Transplantation

Monzr M. Al Malki, Alla Keyzner, Hyung Chan Suh, Aasiya Matin, Erica Buonomo, Yun Wang, Nina Abelowitz, Jim Murray, Gavin Macbeath, Debora Barton, Shrikanta Chattopadhyay, Ran Reshef
Journal: Blood
Blood (2023) 142 (Supplement 1): 2090.
https://doi.org/10.1182/blood-2023-187355
Published: 2023
Journal Articles

Trial in Progress: A Phase 1 Umbrella Study of TCR-Engineered T Cells That Target HA-1 (TSC-100) and HA-2 (TSC-101) to Treat Residual Leukemia after Hematopoietic Cell Transplantation

Ran Reshef, Hyung C. Suh, Monzr M. Al Malki, Aasiya Matin, Ashish S Kothari, Allison Bell, Antoine J Boudot, Yun Wang, Nina Abelowitz, James Murray, Gavin Macbeath, Debora Barton, Shrikanta Chattopadhyay
Journal: Blood
Blood (2022) 140 (Supplement 1): 7468–7469.
https://doi.org/10.1182/blood-2022-167707
Published: 2022
Journal Articles

Discovery of TSC-101: A First-in-Class Natural HA-2-Specific TCR to Treat Leukemia Following Hematopoietic Stem Cell Transplant Therapy

Ribhu Nayar, Mollie M Jurewicz, Sonal Jangalwe, Hannah Bader, Kimberly M Cirelli, Andrew Basinski, Daniel Pollacksmith, Alexandra Luther, Cisem Karaca, Anna Labrozzi, Krista Daniel, Lisa Nip, Danielle Ramsdell, Amy Virbasius, Candace Perullo, Kenneth L Jahan, Sida Liao, Livio Dukaj, Alexandra Cristofaro, Shrikanta Chattopadhyay, Kenneth Olivier, Antoine J Boudot, Qikai Xu, Yifan Wang, Cagan Gurer, Gavin Macbeath
Journal: Blood
Blood (2021) 138 (Supplement 1): 1704.
https://doi.org/10.1182/blood-2021-151317
Published: 2021
Journal Articles

Product Characteristics and Multi-Arm Clinical Trial Design for TSC-100 and TSC-101, TCR-T Cells That Target Leukemia Following Hematopoietic Cell Transplantation

Shrikanta Chattopadhyay, Christopher Malcuit, Ryo Takeuchi, Emmett Hedblom, Warren Jaworowicz, Antoine J Boudot, Hannah Bader, James Murray, Gavin Macbeath
Journal: Blood
Blood (2021) 138 (Supplement 1): 3863.
https://doi.org/10.1182/blood-2021-153844
Published: 2021