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Journal Articles

Niche Transfer of Small Non-Coding RNAs Regulates Hematopoietic Response to Stress

Youmna Kfoury, PhD, Fei Ji, Michael Mazzola, BS, David B Sykes, MD PhD, Anselmo Anthony, Yasutoshi Akiyama, Allison Scherer, PhD, Francois Mercier, MD FRCPC, Nicolas Severe, PhD, Borja Saez, Jefferson Seidl, BA, Ani Papazian, BS, Thomas Brouse, Michael K Mansour, MD PhD, Pavel Ivanov, Ruslan I Sadreyev, PhD, David T. Scadden, MD

Blood (2019) 134 (Supplement_1): 1207.

https://doi.org/10.1182/blood-2019-124794

Published: 2019

Journal Articles

Single Cell Transcriptomic Analysis of the Histone H3 K27M Mutation in Pre-Leukemic Hematopoietic Stem Cells

Meaghan Boileau, BSc, Selin Jessa, BSc, Samantha Worme, BSc, Damien Faury, Nada Jabado, MD PhD, François Mercier, MD, Claudia Kleinman, PhD, Kolja Eppert, MSc, PhD

Blood (2019) 134 (Supplement_1): 3773.

https://doi.org/10.1182/blood-2019-123769

Published: 2019

Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD

Blood (2019) 134 (Supplement_1): 3765.

https://doi.org/10.1182/blood-2019-123604

Published: 2019

Journal Articles

Changes in Tumor Immune Micro-Environment in Diffuse Large B-Cell Lymphoma (DLBCL): A Comparative Study of Relapsed Versus Diagnostic DLBCL

Raoul Santiago, MDMSc, Nathalie Johnson, MD, Svetlana Dmitrienko, MD PhD, Andreas Papadakis, PhD, Naciba Benlimame, PhD, François Mercier, MD, Koren Kathleen Mann, PhD, Sarit Assouline, MD

Blood (2019) 134 (Supplement_1): 3968.

https://doi.org/10.1182/blood-2019-122207

Published: 2019

Journal Articles

A 10-Color Flow Cytometry Panel for Both Diagnosis and Minimal Residual Disease Measurement in Chronic Lymphocytic Leukemia

Alexandre Bazinet, MD, Ryan N Rys, BSc, BA, Claudia M Wever, PhD, Amadou Barry, Celia Greenwood, PhD, Christian Young, Alma Mendoza, Ida LaPorta, Sylvain Gimmig, François Mercier, MD, Nathalie Johnson, MD

Blood (2019) 134 (Supplement_1): 5451.

https://doi.org/10.1182/blood-2019-123904

Published: 2019

Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Blood (2018) 132 (Supplement 1): 55.

https://doi.org/10.1182/blood-2018-99-113916

Published: 2018

Journal Articles

Specific Bone Marrow Mesenchymal Subsets in Patients with Myelodysplastic Syndromes Harbor Molecular Perturbations That Alter the Dynamics of Competition between Pre-Leukemic Clones and Normal Cells

Youmna Kfoury, PhD, Esha Jain, Jason R Myers, MS, Fei Ji, David B Sykes, MD PhD, Francois Mercier, MD FRCPC, Ani Papazian, BS, Cam Le, Mark A Randolph, M.A.Sc., David P. Steensma, MD, Omar I Abdel-Wahab, MD, Laura M. Calvi, MD, Ruslan I Sadreyev, PhD, Michael W. Becker, MD, David T. Scadden, MD

Blood (2018) 132 (Supplement 1): 938.

https://doi.org/10.1182/blood-2018-99-115242

Published: 2018

Journal Articles

Osteoblastic Cell-Derived Extracellular Vesicles Transfer Small RNAs That Alter the Physiology of Hematopoietic Cells In Vivo

Youmna Kfoury, PhD, Anthony Anselmo, PhD, Jefferson Seidl, BA, Ani Papazian, BS, Francois Mercier, MD FRCPC, David B Sykes, MD PhD, Nicolas Severe, PhD, Borja Saez, PhD, Ruslan I Sadreyev, PhD, David T. Scadden, MD

Blood (2017) 130 (Supplement 1): 93.

https://doi.org/10.1182/blood.V130.Suppl_1.93.93

Published: 2017

Journal Articles

A Genome-Wide, In Vivo, Dropout CRISPR Screen in Acute Myeloid Leukemia Identifies an Essential Role for Beta-Galactosylation in Leukemic Cell Homing

Francois Mercier, MD, Jiantao Shi, PhD, David B Sykes, MD PhD, Elizabeth Miller, Toshihiko Oki, MD PhD, Cheuk-Him Man, PhD, Xiao-Jing Yan, MD PhD, Youmna Kfoury, PhD, Dongjun Lee, PhD, John G Doench, PhD, Franziska Michor, PhD, David T. Scadden, MD

Blood (2017) 130 (Supplement 1): 2493.

https://doi.org/10.1182/blood.V130.Suppl_1.2493.2493

Published: 2017

Journal Articles

Inhibition of the Enzyme Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

David B. Sykes, MD PhD, Youmna Sami Kfoury, PhD, Francois Mercier, MD, Mathias Wawer, PhD, Amir Schajnovitz, PhD, Hanna Meyer, PhD, Kerry A Pierce, PhD, Detlef Stoeckigt, PhD, Clary B Clish, PhD, Paul A Clemons, PhD, Andreas Janzer, PhD, David T. Scadden, MD

Blood (2016) 128 (22): 1656.

https://doi.org/10.1182/blood.V128.22.1656.1656

Published: 2016

Journal Articles

In Vivo Analysis of Clonal Evolution of Multiple Myeloma

Yuji Mishima, PhD, Jiantao Shi, PhD, Michele Moschetta, MD, Yujia Shen, PhD, Salomon Manier, MD, Aldo M. Roccaro, MD PhD, Francois Mercier, MD FRCPC, Satoshi Takagi, PhD, Yawara Kawano, MD PhD, Shokichi Tsukamoto, MD PhD, Ilyas Sahin, Antonio Sacco, BS, Kiyohiko Hatake, MD PhD, Franziska Michor, PhD, David T. Scadden, MD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 799.

https://doi.org/10.1182/blood.V128.22.799.799

Published: 2016

Journal Articles

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Jonathan Hoggatt, PhD, Pratibha Singh, PhD, Tiffany Tate, BS, Peter V. Kharchenko, PhD, Amir Schajnovitz, PhD, Ninib Barawnyo, PhD, Francois Mercier, MD, Dwight Morrow, PhD, David T. Scadden, MD, Louis M. Pelus, PhD

Blood (2016) 128 (22): 368.

https://doi.org/10.1182/blood.V128.22.368.368

Published: 2016

Journal Articles

Embigin Regulates HSPC Homing and Quiescence and Acts As a Cell Surface Marker for a Niche Factor-Enriched Subset of Osteolineage Cells

Lev Silberstein, MDPhD, Peter V. Kharchenko, PhD, Youmna Sami Kfoury, PhD, Francois Mercier, MD FRCPC, Raphael Turcotte, Charles P. Lin, Ninib Baryawno, PhD, Nicolas Severe, Tiffany Tate, BS, Jonathan Hoggatt, PhD, David T. Scadden, MD

Blood (2015) 126 (23): 663.

https://doi.org/10.1182/blood.V126.23.663.663

Published: 2015

Journal Articles

Clonal-Heterogeneity and Propensity for Bone Metastasis in Multiple Myeloma

Yuji Mishima, PhD, Michele Moschetta, MD, Jiantao Shi, PhD, Francois Mercier, MD, Salomon Manier, MD, Siobhan Glavey, MD, Michaela R. Reagan, PhD, Yawara Kawano, MD PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Aldo M Roccaro, MD PhD, Winston Hide, PhD, David T. Scadden, MD, Irene M. Ghobrial, MD

Blood (2014) 124 (21): 3370.

https://doi.org/10.1182/blood.V124.21.3370.3370

Published: 2014

Journal Articles

Identification of a Gene Expression Signature Characterizing Clonal Fitness and Dominance in Vivo in a Murine Model of MLL-AF9 Leukemia

Francois Mercier, MD, Jiantao Shi, PhD, David Sykes, MDPhD, Youmna Sami Kfoury, PhD, Rushdia Z. Yusuf, MBBS, MPH, Elizabeth Miller, Radovan Vasic, Alex Zhu, Franziska Michor, PhD, Winston Hide, PhD, David T. Scadden, MD

Blood (2014) 124 (21): 2383.

https://doi.org/10.1182/blood.V124.21.2383.2383

Published: 2014

Journal Articles

Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors

Lev Silberstein, MDPhD, Peter Kharchenko, PhD, Youmna Kfoury, PhD, Francois Mercier, MD, Masatake Osawa, PhD, Jonathan Hoggatt, PhD, Tiffany Tate, Charles Lin, PhD, David T. Scadden, MD

Blood (2014) 124 (21): 773.

https://doi.org/10.1182/blood.V124.21.773.773

Published: 2014

Journal Articles

Aldehyde Dehydrogenase 3a2 (Aldh3a2) Represents a Distinct Metabolic Vulnerability in MLL-AF9 AML Leukemia Initiating Cells

Blood (2012) 120 (21): 208.

https://doi.org/10.1182/blood.V120.21.208.208

Published: 2012

Journal Articles

Expression of Immune Memory Markers CD8 α α and Interleukin−7 Receptor on CD8 + T Cell Subsets among HIV−1 Infected Patients.

Jean Pierre Routy, MD, Francois Mercier, MD, Ahmed Galal, MD, Med-Rachid Boulassel, PhD

Blood (2006) 108 (11): 1256.

https://doi.org/10.1182/blood.V108.11.1256.1256

Published: 2006

NARROW

Niche Transfer of Small Non-Coding RNAs Regulates Hematopoietic Response to Stress

Single Cell Transcriptomic Analysis of the Histone H3 K27M Mutation in Pre-Leukemic Hematopoietic Stem Cells

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Changes in Tumor Immune Micro-Environment in Diffuse Large B-Cell Lymphoma (DLBCL): A Comparative Study of Relapsed Versus Diagnostic DLBCL

A 10-Color Flow Cytometry Panel for Both Diagnosis and Minimal Residual Disease Measurement in Chronic Lymphocytic Leukemia

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Specific Bone Marrow Mesenchymal Subsets in Patients with Myelodysplastic Syndromes Harbor Molecular Perturbations That Alter the Dynamics of Competition between Pre-Leukemic Clones and Normal Cells

Osteoblastic Cell-Derived Extracellular Vesicles Transfer Small RNAs That Alter the Physiology of Hematopoietic Cells In Vivo

A Genome-Wide, In Vivo, Dropout CRISPR Screen in Acute Myeloid Leukemia Identifies an Essential Role for Beta-Galactosylation in Leukemic Cell Homing

Inhibition of the Enzyme Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

In Vivo Analysis of Clonal Evolution of Multiple Myeloma

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell

Embigin Regulates HSPC Homing and Quiescence and Acts As a Cell Surface Marker for a Niche Factor-Enriched Subset of Osteolineage Cells

Clonal-Heterogeneity and Propensity for Bone Metastasis in Multiple Myeloma

Identification of a Gene Expression Signature Characterizing Clonal Fitness and Dominance in Vivo in a Murine Model of MLL-AF9 Leukemia

Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors

Aldehyde Dehydrogenase 3a2 (Aldh3a2) Represents a Distinct Metabolic Vulnerability in MLL-AF9 AML Leukemia Initiating Cells

Expression of Immune Memory Markers CD8 α α and Interleukin−7 Receptor on CD8 + T Cell Subsets among HIV−1 Infected Patients.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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