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Journal Articles

Rker-050, a Novel Activin Receptor Type II Ligand Trap, Rescued Anemia and Reduced Bone Loss in a Mouse Model of Myelodysplastic Syndromes

Blake S Moses, Chris Materna, Remya Nathan, Tandicka Nurse, Keith Babbs, Claire Tseng, Ffolliott Fisher, Jasbir Seehra, Jenn Lachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 9763–9764.
https://doi.org/10.1182/blood-2022-169360
Published: 2022
Journal Articles

ALK2 Inhibition and a Modified Activin Receptor Type Iia Ligand Trap Cotherapy Maximized Hematologic Improvements in a Mouse Model of Anemia of Inflammation

Chia-Yu Wang, Emiliano Melgar-Bermudez, Diana Welch, Claire C Tseng, Ffolliott Fisher, Samuel M Cadena, Lorena Lerner, Jasbir Seehra, Jenn Lachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 5337–5338.
https://doi.org/10.1182/blood-2022-166838
Published: 2022
Journal Articles

Ker-050, an Inhibitor of TGF- β Superfamily Signaling, Promoted Thrombopoiesis and Reversed Immune Thrombocytopenia in a Mouse Model of Disease

Marina Feigenson, Remya Nathan, Joshua Lamora, Ffolliott Fisher, Claire C Tseng, Jasbir Seehra, Jenn Lachey
Journal: Blood
Blood (2021) 138 (Supplement 1): 2068.
https://doi.org/10.1182/blood-2021-152814
Published: 2021
Journal Articles

A Monoclonal Antibody Targeting ALK2 As a Potential Therapeutic Agent for Anemia of Inflammation

Natalia Medeiros, Thomas A Backus, Christopher Materna, Ffolliott Fisher, Jenn Lachey, Jasbir Seehra
Journal: Blood
Blood (2021) 138 (Supplement 1): 2007.
https://doi.org/10.1182/blood-2021-153160
Published: 2021
Journal Articles

Rker-050 Rescued Ruxolitinib (Rux)-Associated Reductions in Red Blood Cell Volume

Remya Nathan, Marina Feigenson, Joshua Lamora, Claire C Tseng, Ffolliott Fisher, Jasbir Seehra, Jenn Lachey
Journal: Blood
Blood (2021) 138 (Supplement 1): 934.
https://doi.org/10.1182/blood-2021-152729
Published: 2021
Journal Articles

Ker-050, a Novel Inhibitor of Tgfβ Superfamily Signaling, Induces Red Blood Cell Production By Promoting Multiple Stages of Erythroid Differentiation

Marina Feigenson, PhD, Remya Nathan, Christopher Materna, Alana Gudelsky, Evan Lema, Claire C Tseng, PhD, Ffolliott Fisher, Jasbir Seehra, Jenn Lachey
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-140364
Published: 2020
Journal Articles

Selective Inhibition of ALK2 Signaling Suppresses Serum Hepcidin and Increases Serum Iron

Thomas A Backus, Natalia Medeiros, Evan Lema, Ffolliott Fisher, Jasbir Seehra, Jennifer Lachey
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
https://doi.org/10.1182/blood-2020-139486
Published: 2020
Journal Articles

Ker-050, a Modified Actriia Ligand Trap, Alleviates Cytopenia Arising from Multiple Etiologies

Marina Feigenson, PhD, Remya Nathan, Keith Babbs, Christopher Materna, Claire C Tseng, PhD, Ffolliott Fisher, Jasbir Seehra, Jenn Lachey
Journal: Blood
Blood (2020) 136 (Supplement 1): 38.
https://doi.org/10.1182/blood-2020-140167
Published: 2020