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Journal Articles

Abatacept Abrogates the Risk of Acute GvHD in Both Matched and Mismatched Transplantation for Haemoglobinopathies and Bone Marrow Failure

Daniel Dexter, Farah O'Boyle, Kirstin Lund, Toni Petterson, Adam Gassas, Leena Karnik, Josu de la Fuente, Sandrine Bremathas, Kelly Hennessy

Blood (2024) 144 (Supplement 1): 3518.

https://doi.org/10.1182/blood-2024-208717

Published: 2024

Journal Articles

Donor Trait Status Determines Haematological Outcomes Post-Haemopoietic Stem Cell Transplantation in Transfusion Dependent Thalassaemia Independent of HLA Matching and Chimerism Status

Kinza Khan, Farah O'Boyle, Kirstin Lund, Toni Petterson, Sandrine Bremathas, Kelly Hennessy, Adam Gassas, Leena Karnik, Josu de la Fuente

Blood (2024) 144 (Supplement 1): 1097.

https://doi.org/10.1182/blood-2024-211100

Published: 2024

Journal Articles

Immune Graft Composition Is Important for Deepening Response and Outcome after Autologous Stem Cell Transplantation in Patients with Multiple Myeloma Who Do Not Receive Maintenance Therapy

Yeasung Lee, Francesca Bladt, Dimitrios Leonardos, Chira Mustafa, Alexia Katsarou, Maria Atta, Marco Bua, Ian Gabriel, Jose Ros-Soto, Alexandra Bazeos, Jiri Pavlu, Sandra Loaiza, Emma Bray, Farah O'Boyle, Elisabet Nadal, Richard Szydlo, Nicholas Crump, Anastasios Karadimitris, Aristeidis Chaidos

Blood (2023) 142 (Supplement 1): 759.

https://doi.org/10.1182/blood-2023-188912

Published: 2023

Journal Articles

Effective Desensitization Strategy for Patients with Sickle Cell Disease with High Donor Specific Antibodies Undergoing Haploidentical Bone Marrow Transplant with Posttransplant Cyclophosphamide

Eden Biltibo, Reena Jayani, Leena Karnik, Adam Gassas, Farah O'Boyle, Daniel Dexter, Karina Wilkerson, Katie S. Gatwood, Lindsay Orton, Bhagirathbhai Dholaria, Bipin N. Savani, Brian G. Engelhardt, Salyka M. Sengsayadeth, Carrie Lynn Kitko, James P Connelly, Adetola A. Kassim, Josu de la Fuente

Blood (2022) 140 (Supplement 1): 7613–7615.

https://doi.org/10.1182/blood-2022-162825

Published: 2022

Journal Articles

Nonmyeloablative Transplant for Sickle Cell Disease Does Not Lead to Kidney Dysfunction Post-HSCT

Emily Limerick, Santosh L. Saraf, Neal Jeffries, Farah O'Boyle, Clarissa Diamantidis, Yuliya Lokhnygina, Matthew M. Hsieh, Josu de la Fuente, Courtney D. Fitzhugh

Blood (2021) 138 (Supplement 1): 984.

https://doi.org/10.1182/blood-2021-153230

Published: 2021

Journal Articles

Complex Clonal Evolution Can Occur Following Transplantation for Transfusion Dependent Thalassaemia in the Context of Mixed Myeloid Chimerism and Reduced Conditioning Regimens

Adam Gassas, Farah O'Boyle, Shahzya Chaudhury, Toni Petterson, Kirstin Lund, Leena Karnik, Josu de la Fuente

Blood (2021) 138 (Supplement 1): 2906.

https://doi.org/10.1182/blood-2021-153519

Published: 2021

Journal Articles

Results of Unrelated Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease in Europe on Behalf of Paediatric Diseases (PDWP) and Inborn Errors Working Parties (IEWP) of the EBMT

Blood (2019) 134 (Supplement_1): 4583.

https://doi.org/10.1182/blood-2019-121952

Published: 2019

Journal Articles

Clustering Analysis of Myeloma Clone Phenotype Is Informative for Disease Heterogeneity and Prognosis at Relapse

Syeda Maheen Ahsan, Elisabet Nadal-Melsio, MD, Mark E Robinson, PhD, Richard Syzdlo, PhD, Eva Yebra-Fernandez, MD, Holger W Auner, MD PhD, Maria Atta, MD, Marco Bua, MD, Farah O'Boyle, PhD, Kikkeri Naresh, Jane Apperley, MB ChB MD, Anastasios Karadimitris, FRCPath, PhD, Aristeidis Chaidos, MD PhD

Blood (2018) 132 (Supplement 1): 4492.

https://doi.org/10.1182/blood-2018-99-117460

Published: 2018

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in b Thalassaemia Major Leads to Early and Sustained Engraftment with Low Incidence of VOD and GvHD but a High Rate of Long-Term Mixed Chimerism

Farah O'Boyle, PhD, Leena Karnik, FRCPath, MRCP, Kirstin Lund, MRCP, BSc, Richard Szydlo, PhD, Josu de la Fuente, FRCP, PhD FRCPath

Blood (2017) 130 (Supplement 1): 3323.

https://doi.org/10.1182/blood.V130.Suppl_1.3323.3323

Published: 2017

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in β Thalassaemia Major Leads to Early and Sustained Engraftment with Low Incidence of VOD and GvHD

Farah O'Boyle, PhD, Leena Karnik, MD FRCPath, MBBS,, Anne Bradshaw, Richard M Szydlo, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath

Blood (2016) 128 (22): 1283.

https://doi.org/10.1182/blood.V128.22.1283.1283

Published: 2016

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Matched and Single Antigen Mismatched Unrelated Bone Marrow Transplantation in Haemoglobinopathies Is Feasible and Leads to Early and Sustanined Engraftment with No Long-Term Toxicity or GvHD

Farah O'Boyle, PhD, Leena Karnik, MD FRCPath, MBBS,, Anne Bradshaw, Richard M Szydlo, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath

Blood (2016) 128 (22): 2468.

https://doi.org/10.1182/blood.V128.22.2468.2468

Published: 2016

Journal Articles

Haemopoietic Stem Cell Transplantation for Diamond Blackfan Anaemia Leads to Early and Sustained Engraftment with Good Long-Term Outcomes, but Has an Increased Risk of Gut Toxicity and Lung GvHD

Farah O'Boyle, PhD, Anne Bradshaw, Richard M Szydlo, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath

Blood (2016) 128 (22): 2679.

https://doi.org/10.1182/blood.V128.22.2679.2679

Published: 2016

Journal Articles

Haploidentical BMT with a Post-Infusion of Stem Cells Cyclophosphamide Approach Is Feasible and Leads to a High Rate of Donor Engraftment in Haemoglobinopathies Allowing Universal Application of Transplantation

Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath, Farah O'Boyle, PhD, Yvonne Harrington, Anne Bradshaw, Sandra Hing, PhD, Subarna Chakravorty, PhD FRCPath, Leena Karnik, MD FRCPath, MBBS,, Helen New, PhDFRCPath, Richard Szydlo, PhD, Baba PD Inusa, MBBS, FMCPaed, FRCPCH, MRCP, DCP, Paul Telfer, FRCPath,MD

Blood (2015) 126 (23): 4317.

https://doi.org/10.1182/blood.V126.23.4317.4317

Published: 2015

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in Haemoglobinopathies Leads to Early and Sustanined Engraftment with Low Incidence of VOD and GvHD

Farah O'Boyle, PhD, Sandra Hing, PhD, Yvonne Harrington, Subarna Chakravorty, PhD FRCPath, Leena Karnik, MD FRCPath, MBBS,, Helen New, PhDFRCPath, Anne Bradshaw, Richard Szydlo, PhD, Josu de la Fuente, PhD FRCP, FRCPI, FRCPCH, FRCPath

Blood (2015) 126 (23): 1906.

https://doi.org/10.1182/blood.V126.23.1906.1906

Published: 2015

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning Leads To High Rates Of Long-Term Engraftment and Low Toxicity Enabling The Use Of Mismatched and Unrelated Donors For Transplantation In Haemoglobinopathies

Josu de la Fuente, PhD, FRCP, MRCPCH, FRCPath, Farah O'Boyle, PhD, Yvonne Harrington, RCN, Nancy O'Brien, RCN, Natalie Killeen, Subarna Chakravorty, PhD, FRCPath, MRCPCH, Leena Karnik, FRCPath, Richard Szydlo, PhD, Irene Roberts, MD FRCP FRCPCH FRCPath

Blood (2013) 122 (21): 2041.

https://doi.org/10.1182/blood.V122.21.2041.2041

Published: 2013

Journal Articles

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning Leads to Earlier Engraftment and Higher Donor Chimerism Than Busulfan/Cyclophosphamide, and Enables the Use of Mismatched and Unrelated Donors for Transplantation in Haemoglobinopathies

Farah O'Boyle, PhD, Natalie Killeen, Mikel Valganon, BSc, Subarna Chakravorty, PhD, FRCPath, MRCPCH, Leena Karnik, FRCPath, Helen New, PhD, FRCP, FRCPath, Letizia Foroni, MD, PhD, Richard Szydlo, PhD, Irene Roberts, Josu de la Fuente, PhD, FRCP, MRCPCH, FRCPath

Blood (2012) 120 (21): 3234.

https://doi.org/10.1182/blood.V120.21.3234.3234

Published: 2012

Journal Articles

Elevated Preconditioning Serum Levels of C-Reactive Protein Are Associated with Increased Nonrelapse Mortality and Inferior Survival After Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation

Jiri Pavlu, Katayoun Rezvani, Bhuvan Kishore, Rifca Le Dieu, Joydeep Chakrabartty, Aristeidis Chaidos, Edward J Kanfer, Anastasios Karadimitris, Donald H MacDonald, David Marin, Dragana Milojkovic, MD, Farah O'Boyle, Amin Rahemtulla, David Slade, John M Goldman, Jane F Apperley, MBChB, MD, FRCP, FRCPath, Richard M Szydlo

Blood (2011) 118 (21): 1945.

https://doi.org/10.1182/blood.V118.21.1945.1945

Published: 2011

Journal Articles

Bone Marrow Transplantation Arrests Cerebrovascular Disease Progression and Improves Psychometric Outcomes in Children with Sickle Cell Disease

Neha Bhatnagar, MBChB, MRCPCH, Ruth Erskine, Farah O'Boyle, Subarna Chakravorty, PhD, FRCPath, MRCPCH, Irene Roberts, MD, Josu de la Fuente, PhD, FRCP, FRCPath

Blood (2011) 118 (21): 11.

https://doi.org/10.1182/blood.V118.21.11.11

Published: 2011

Journal Articles

Rapid Recovery of CD4 Counts Following Low Dose Alemtuzumab Conditioning During HLA Matched Related Bone Marrow Transplant for Children with Haemoglobinopathies

Lucy Cook, MRCP, FRCPath, Farah O'Boyle, MRCP, FRCPath, Leena Karnik, MRCP, FRCPath, Helen New, FRCP, FRCPath, Irene Roberts, MD, Josu de la Fuente, FRCP, FRCPath

Blood (2010) 116 (21): 2335.

https://doi.org/10.1182/blood.V116.21.2335.2335

Published: 2010

Journal Articles

Veno-Occlusive Disease After Haematopoietic Stem Cell Transplantation for β Thalassaemia Major Is Predicted by the Severity of Hepatic Fibrosis and Ameliorated by Defibrotide

Prashant Hiwarkar, Farah O'Boyle, Leena Karnik, Helen New, FRCP, FRCPath, Richard Szydlo, Irene Roberts, MD, Josu de la Fuente, FRCP, FRCPath

Blood (2010) 116 (21): 1330.

https://doi.org/10.1182/blood.V116.21.1330.1330

Published: 2010

NARROW

Abatacept Abrogates the Risk of Acute GvHD in Both Matched and Mismatched Transplantation for Haemoglobinopathies and Bone Marrow Failure

Donor Trait Status Determines Haematological Outcomes Post-Haemopoietic Stem Cell Transplantation in Transfusion Dependent Thalassaemia Independent of HLA Matching and Chimerism Status

Immune Graft Composition Is Important for Deepening Response and Outcome after Autologous Stem Cell Transplantation in Patients with Multiple Myeloma Who Do Not Receive Maintenance Therapy

Effective Desensitization Strategy for Patients with Sickle Cell Disease with High Donor Specific Antibodies Undergoing Haploidentical Bone Marrow Transplant with Posttransplant Cyclophosphamide

Nonmyeloablative Transplant for Sickle Cell Disease Does Not Lead to Kidney Dysfunction Post-HSCT

Complex Clonal Evolution Can Occur Following Transplantation for Transfusion Dependent Thalassaemia in the Context of Mixed Myeloid Chimerism and Reduced Conditioning Regimens

Results of Unrelated Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease in Europe on Behalf of Paediatric Diseases (PDWP) and Inborn Errors Working Parties (IEWP) of the EBMT

Clustering Analysis of Myeloma Clone Phenotype Is Informative for Disease Heterogeneity and Prognosis at Relapse

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in b Thalassaemia Major Leads to Early and Sustained Engraftment with Low Incidence of VOD and GvHD but a High Rate of Long-Term Mixed Chimerism

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in β Thalassaemia Major Leads to Early and Sustained Engraftment with Low Incidence of VOD and GvHD

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Matched and Single Antigen Mismatched Unrelated Bone Marrow Transplantation in Haemoglobinopathies Is Feasible and Leads to Early and Sustanined Engraftment with No Long-Term Toxicity or GvHD

Haemopoietic Stem Cell Transplantation for Diamond Blackfan Anaemia Leads to Early and Sustained Engraftment with Good Long-Term Outcomes, but Has an Increased Risk of Gut Toxicity and Lung GvHD

Haploidentical BMT with a Post-Infusion of Stem Cells Cyclophosphamide Approach Is Feasible and Leads to a High Rate of Donor Engraftment in Haemoglobinopathies Allowing Universal Application of Transplantation

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning for Related Transplantation in Haemoglobinopathies Leads to Early and Sustanined Engraftment with Low Incidence of VOD and GvHD

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning Leads To High Rates Of Long-Term Engraftment and Low Toxicity Enabling The Use Of Mismatched and Unrelated Donors For Transplantation In Haemoglobinopathies

Fludarabine/Treosulfan/Thiotepa/ATG Conditioning Leads to Earlier Engraftment and Higher Donor Chimerism Than Busulfan/Cyclophosphamide, and Enables the Use of Mismatched and Unrelated Donors for Transplantation in Haemoglobinopathies

Elevated Preconditioning Serum Levels of C-Reactive Protein Are Associated with Increased Nonrelapse Mortality and Inferior Survival After Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation

Bone Marrow Transplantation Arrests Cerebrovascular Disease Progression and Improves Psychometric Outcomes in Children with Sickle Cell Disease

Rapid Recovery of CD4 Counts Following Low Dose Alemtuzumab Conditioning During HLA Matched Related Bone Marrow Transplant for Children with Haemoglobinopathies

Veno-Occlusive Disease After Haematopoietic Stem Cell Transplantation for β Thalassaemia Major Is Predicted by the Severity of Hepatic Fibrosis and Ameliorated by Defibrotide

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American Society of Hematology

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