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Etienne De Braekeleer, PhD
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Journal Articles

Setbp1 Overexpression Acts in the Place of Class-Defining Somatic Mutations to Drive Mouse and Human FLT3-ITD -Mutant AMLs

Suruchi Pacharne, Oliver M. Dovey, PhD, Jonathan L Cooper, Muxin Gu, Vijay Baskar, PhD, Mathias J Friedrich, Malgorzata Gozdecka, PhD, Sandeep S Rajan, PhD, Etienne De Braekeleer, PhD MSc, Maxim Barenboim, Grace Collord, Hannes Postingl, PhD, Ruben Bautista, Milena Mazan, PhD, Roland Rad, Prof., MD, Konstantinos Tzelepis, Penny Wright, George S. Vassiliou, MD PhD FRCPath, MRCP
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-141743
Published: 2020
Journal Articles

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Konstantinos Tzelepis, Etienne De Braekeleer, PhD MSc, Eliza Yankova, PhD, Justyna Rak, PhD, Demetrios Aspris, MSc, Ana Filipa Domingues, PhD, Richard Fosbeary, Alan Hendrick, PhD, Dan Leggate, PhD, Yaara Ofir-Rosenfeld, PhD, Alexandra Sapetschnig, PhD, Cristina Pina, MDDPhil, Mark Albertella, PhD, Wesley Blackaby, PhD, Oliver Rausch, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Tony Kouzarides, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 403.
https://doi.org/10.1182/blood-2019-127962
Published: 2019
Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou
Journal: Blood
Blood (2018) 132 (Supplement 1): 2615.
https://doi.org/10.1182/blood-2018-99-118827
Published: 2018
Journal Articles

High Prevalence of PPM1D Mutations in Therapy-Related AML/MDS Is Due to Context-Specific Clonal Hematopoiesis

Joanne Hsu, BS, Tajhal Dayaram, Ayala Tovy, PhD, Etienne De Braekeleer, PhD MSc, Mira Jeong, PhD, Jason H. Rogers, MS, Feng Wang, PhD, Jianhua Zhang, PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, George S. Vassiliou, Andrew Futreal, PhD, Lawrence Donehower, Koichi Takahashi, MD, Margaret Goodell, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 746.
https://doi.org/10.1182/blood-2018-99-115007
Published: 2018
Journal Articles

SRPK1 Is a Therapeutic Vulnerability in Acute Myeloid Leukemia through Its Effects on Alternative Isoforms of Epigenetic Regulators Including BRD4

Konstantinos Tzelepis, PhD, Etienne De Braekeleer, PhD, Isaia Barbieri, PhD, Vijay Baskar, PhD, Demetrios Aspris, MSc, Francisco Hermida Prado, PhD, Malgorzata Gozdecka, PhD, Monika Dudek, MSc, Hannes Postingl, PhD, David Bates, PhD, Andrew Bannister, PhD, Brian J.P Huntly, Cristina Pina, MDDPhil, Allan Bradley, PhD, Kosuke Yusa, PhD, Tony Kouzarides, PhD, George S. Vassiliou, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 781.
https://doi.org/10.1182/blood.V130.Suppl_1.781.781
Published: 2017
Journal Articles

A Crispr/Cas9 Drop-out Screen Identifies Genome-Wide Genetic Valnerubilities in Acute Myeloid Leukaemia

Konstantinos Tzelepis, MSc, Hiroko Koike-Yusa, MD, Etienne De Braekeleer, PhD, Yilong Li, Emmanouil Metzakopian, PhD, Oliver M. Dovey, PhD, Annalisa Mupo, PhD, Vera Grinkevich, PhD, Milena M. Mazan, PhD, Malgorzata Gozdecka, PhD, Jonathan L. Cooper, Miten Patel, MD, Thomas David Hardman McKerrell, MD, Bin Chen, Hannes Ponstingl, PhD, Brian J.P Huntly, MD PhD, Ultan McDermott, MD PhD, Julio Saez-Rodriguez, PhD, Francesco Iorio, PhD, Kosuke Yusa, PhD, George S. Vassiliou, MD PhD
Journal: Blood
Blood (2015) 126 (23): 554.
https://doi.org/10.1182/blood.V126.23.554.554
Published: 2015