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Erwin Boghaert
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Journal Articles

Pevonedistat, a Nedd-8 Activating Enzyme Inhibitor, Upregulates NOXA to Increase Effectiveness of Azacitidine and Venetoclax in Preclinical Models of Acute Myelogenous Leukemia

Brianna N Smith, MD MS, Dan Cojocari, PhD BSc, Julie J Purkal, MA, Maria Arrate, MSc, Haley E. Ramsey, PhDMSc, Joel D. Leverson, PhD, Erwin Boghaert, MS, MD, Darren C. Phillips, PhD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1380.
https://doi.org/10.1182/blood-2019-123068
Published: 2019
Journal Articles

5-Azacytidine Induces NOXA and PUMA Expression to Prime AML Cells for Venetoclax-Mediated Apoptosis

Dan Cojocari, PhD BSc, Sha Jin, MS, Julie J Purkal, MA, Relja Popovic, PhD, Nari N Talaty, PhD, Yu Xiao, MS, Larry R Solomon, PhD, Erwin Boghaert, MS, MD, Joel D. Leverson, PhD, Darren C. Phillips, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2644.
https://doi.org/10.1182/blood-2018-99-111985
Published: 2018
Journal Articles

FLT3-ITD Activation Mediates Resistance to the BCL-2 Selective Antagonist, Venetoclax, in FLT3-ITD Mutant AML Models

Raghuveer Singh Mali, PhD, Elisabeth A. Lasater, PhD, Kelly Doyle, Ritu Malla, Erwin Boghaert, Andrew Souers, Joel D. Leverson, PhD, Deepak Sampath, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1348.
https://doi.org/10.1182/blood.V130.Suppl_1.1348.1348
Published: 2017