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Journal Articles

Lin - Sca-1 + c-Kit low CD48 + CD71 + Cells Are the Engine of Bone Marrow Regeneration

Emanuel Necas, MD PhD, Katarina Szikszai-Forgacova, PhD, Katerina Faltusova, Ludek Sefc, PhD, Filipp Savvulidi, Petr Paral, Martin Molik

Blood (2014) 124 (21): 5112.

https://doi.org/10.1182/blood.V124.21.5112.5112

Published: 2014

Journal Articles

Down-Regulation of c-Kit Receptor on Hematopoietic Cells By Stem Cell Factor (SCF; c-Kit-ligand): No Impact on Transplantation

Emanuel Necas, MD, PhD, Chia-Ling Chen, Katerina Faltusova, Ko-Tung Chang, PhD

Blood (2014) 124 (21): 5115.

https://doi.org/10.1182/blood.V124.21.5115.5115

Published: 2014

Journal Articles

Mouse Models of Human Mantle Cell Lymphoma for the Study of Disease Biology and for Pre-Clinical Assessment of Experimental Treatment Approaches.

Pavel Klener, Jr., MD, PhD, Magdalena Klanova, MD, Tomas Soukup, MD, Jan Molinsky, MD, Jan Zivny, MD, PhD, Marek Trneny, MD, Francisco J. Hernandez-Ilizaliturri, MD, Myron S. Czuczman, MD, Emanuel Necas, MD, PhD

Blood (2012) 120 (21): 2759.

https://doi.org/10.1182/blood.V120.21.2759.2759

Published: 2012

Journal Articles

CD31/PECAM-1 Is Overexpressed On Mantle-Cell Lymphoma (MCL) Primary Cells and Positively Regulates Engraftment and Growth of MCL Cell Lines in Immunodeficient Mice.

Jan Molinsky, MD, Magdalena Klanova, MD, Bokang Maswabi, MD, Josef Karban, MD, Martin Spacek, MD, Marek Trneny, MD, Emanuel Necas, MD, PhD, Jan Zivny, MD, PhD, Pavel Klener, Jr., MD, PhD

Blood (2012) 120 (21): 2681.

https://doi.org/10.1182/blood.V120.21.2681.2681

Published: 2012

Journal Articles

Activation of Chromatin Structure Upstream PU.1 Gene and in Vitro Differentiation in High Risk Myelodysplastic Syndrome Following 5-Azacytidine,

Tomas Stopka, MD, PhD, Nikola Curik, Pavel Burda, PhD, Karin Vargova, Vit Pospisil, Petra Vlckova, Filipp Savvulidi, Emanuel Necas, Hana Hájková, Cedrik Haskovec, PhD, Monika Belickova, Jaroslav Cermak, MD, PhD, Marek Trneny, Anna Jonasova, MD

Blood (2011) 118 (21): 3791.

https://doi.org/10.1182/blood.V118.21.3791.3791

Published: 2011

Journal Articles

Pattern of Mir-155 and PU.1 Expression in CLL/SLL and Aggressive Lymphomas

Tomas Stopka, MD, PhD, Karin Vargova, Hana Huskova, Pavel Burda, PhD, Nikola Curik, Petra Vlckova, Vojtech Kulvait, Vit Pospisil, Filipp Savvulidi, Emanuel Necas, Marek Mraz, MD, Sarka Pospisilova, Dr, PhD, Jiri Mayer, MD, PhD, Josef Karban, Petra Obrtlikova, MD, PhD, Marek Trneny

Blood (2011) 118 (21): 4600.

https://doi.org/10.1182/blood.V118.21.4600.4600

Published: 2011

Journal Articles

MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia

Karin Vargova, Nikola Curik, Pavel Burda, Petra Basova, Vojtech Kulvait, Vit Pospisil, Filipp Savvulidi, Juraj Kokavec, Emanuel Necas, Adela Berkova, Petra Obrtlikova, Josef Karban, Marek Mraz, Sarka Pospisilova, Jiri Mayer, Marek Trneny, Jiri Zavadil, Tomas Stopka

Blood (2011) 117 (14): 3816–3825.

https://doi.org/10.1182/blood-2010-05-285064

Published: 2011

Includes: Supplemental data

Journal Articles

Roscovitine Sensitizes Leukemia and Lymphoma Cells to TRAIL-Induced Apoptosis and Enhances Cell-Mediated Cytotoxicity

Jan Molinsky, Marie Markova, Magdalena Klanova, Michal Koc, Lenka Beranova, Ladislav Andera, Zdenka Ludvikova, Martina Bohmova, Zdenka Gasova, Marek Trneny, Emanuel Necas, Jan Zivny, Pavel Klener

Blood (2010) 116 (21): 596.

https://doi.org/10.1182/blood.V116.21.596.596

Published: 2010

Journal Articles

Mobilization with Cyclophosphamide Shifts Hematopoiesis From the Bone Marrow to the Spleen In Mouse.

Ludek Sefc, Ko-Tung Chang, Viktor Sykora, Emanuel Necas

Blood (2010) 116 (21): 1590.

https://doi.org/10.1182/blood.V116.21.1590.1590

Published: 2010

Journal Articles

Hematopoietic Stem Cells Survive Warm Ischemia and the Bone Marrow Upregulates a Significant Number of Genes

Jana Michalova, Ludek Sefc, Filipp Savvulidi, Katarina Forgacova, Katerina Faltusova, Ko-Tung Chang, Emanuel Necas

Blood (2010) 116 (21): 4694.

https://doi.org/10.1182/blood.V116.21.4694.4694

Published: 2010

Journal Articles

Active Chromatin Structure near MYB Occupancy at the Mir-155 Host Gene Promoter Coincides with Increased Mir-155 and MYB Levels In Chronic Lymphocytic Leukemia

Tomas Stopka, MD, PhD, Karin Vargova, Nikola Curik, Pavel Burda, Petra Basova, Vit Pospisil, Vojtech Kulvait, Filipp Savvulidi, Emanuel Necas, MD, PhD, Adela Berkova, MD, Petra Obrtlikova, MD, Josef Karban, MD, Marek Trneny, MD, PhD, Jiri Zavadil, PhD

Blood (2010) 116 (21): 3589.

https://doi.org/10.1182/blood.V116.21.3589.3589

Published: 2010

Journal Articles

Transplantation Window Created by Bone Marrow Irradiation and Its Closure.

Forgacova Katarina, Ludek Sefc, Jana Michalova, Filipp Savvulidi, Ko-Tung Chang, Emanuel Necas

Blood (2010) 116 (21): 3713.

https://doi.org/10.1182/blood.V116.21.3713.3713

Published: 2010

Journal Articles

The Oncogenic Mir-17-92 MicroRNA Cluster Is Inhibited by EGR2 During Macrophage Differentiation Via JARID1b-Mediated Histone 3 Lysine 4 Demethylation

Vit Pospisil, Karin Vargova, Juraj Kokavec, Jana Rybarova, Filipp Savvulidi, Emanuel Necas, Peter Laslo, PhD, Jiri Zavadil, PhD, Tomas Stopka, MD, PhD

Blood (2010) 116 (21): 390.

https://doi.org/10.1182/blood.V116.21.390.390

Published: 2010

Journal Articles

ISWI Chromatin Remodeling ATPase Smarca5 (Snf2h) Is Required for Murine Erythroid Development and Globin Gene Regulation

Juraj Kokavec, Romit Majumdar, PhD, Martina Kapalova, Nikola Curik, Filipp Savvulidi, Emanuel Necas, Arthur I. Skoultchi, PhD, Tomas Stopka, MD, PhD

Blood (2010) 116 (21): 2062.

https://doi.org/10.1182/blood.V116.21.2062.2062

Published: 2010

Journal Articles

Upregulation of Caspase 10 Contributes to Acquired Resistance of Acute T-Lymphoblastic Leukemia Cells to Proapoptotic Cytokine TRAIL.

Pavel Klener, Jr., Jan Molinsky, Marie Markova, Sergiu Leahomschi, Tereza Simonova, Ladislav Andera, Emanuel Necas, Jan Zivny

Blood (2009) 114 (22): 3790.

https://doi.org/10.1182/blood.V114.22.3790.3790

Published: 2009

Journal Articles

Transcription Factors PU.1 and EGR2 Inhibits the Oncogenic Microrna Cluster Mir-17-92 during Macrophage Differentiation

Vit Pospisil, Karin Vargova, Pavel Burda, Juraj Kokavec, Emanuel Necas, Jiri Zavadil, Tomas Stopka, MD, PhD

Blood (2008) 112 (11): 473.

https://doi.org/10.1182/blood.V112.11.473.473

Published: 2008

Journal Articles

Acquired Resistance to Tumor Necrosis Factor-Related Apoptosis- Inducing Ligand (TRAIL): Histone Deacetylase Inhibitors Resensitize TRAIL-Resistant Jurkat Acute Lymphocytic Leukemia Cells

Pavel Klener, Jr., Jan Molinsky, Tereza Simonova, Emanuel Necas, Ladislav Andera, Jan Zivny

Blood (2008) 112 (11): 5032.

https://doi.org/10.1182/blood.V112.11.5032.5032

Published: 2008

Journal Articles

Proteomic and mRNA Expression Chip Analysis of Acquired TRAIL-Resistance in Human HL60 Myeloid Leukemia Cells.

Jan Zivny, MD, PhD, Pavel Klener, MD, Ondrej Toman, PhD, Petr Halada, PhD, Robert Ivanek, Tereza Simonova, Ladislav Andera, PhD, Emanuel Necas, MD,DrSc, Jiri Petrak, PhD

Blood (2007) 110 (11): 4155.

https://doi.org/10.1182/blood.V110.11.4155.4155

Published: 2007

Journal Articles

Genome-Wide and Functional Analysis of Acquired Resistance to TRAIL/APO2l Mediated Apoptosis of Leukemia Cell Lines.

Jan Zivny, MD,PhD, Pavel Klener, MD, Pavel Prochazka, MD, Sergiu Laehomschi, Ales Vicha, MD,PhD, Tomas Eckschlager, MD,PhD, Ladislav Andera, PhD, Emanuel Necas, MD,PhD

Blood (2006) 108 (11): 4385.

https://doi.org/10.1182/blood.V108.11.4385.4385

Published: 2006

Journal Articles

PU.1 Activity Determines Fate of Myeloid Progenitor Cells during Lineage Commitment.

Vitek Pospisil, MSc, Emanuel Necas, MD, PhD, Tomas Stopka, MD, PhD

Blood (2006) 108 (11): 4207.

https://doi.org/10.1182/blood.V108.11.4207.4207

Published: 2006

NARROW

Lin - Sca-1 + c-Kit low CD48 + CD71 + Cells Are the Engine of Bone Marrow Regeneration

Down-Regulation of c-Kit Receptor on Hematopoietic Cells By Stem Cell Factor (SCF; c-Kit-ligand): No Impact on Transplantation

Mouse Models of Human Mantle Cell Lymphoma for the Study of Disease Biology and for Pre-Clinical Assessment of Experimental Treatment Approaches.

CD31/PECAM-1 Is Overexpressed On Mantle-Cell Lymphoma (MCL) Primary Cells and Positively Regulates Engraftment and Growth of MCL Cell Lines in Immunodeficient Mice.

Activation of Chromatin Structure Upstream PU.1 Gene and in Vitro Differentiation in High Risk Myelodysplastic Syndrome Following 5-Azacytidine,

Pattern of Mir-155 and PU.1 Expression in CLL/SLL and Aggressive Lymphomas

MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia

Roscovitine Sensitizes Leukemia and Lymphoma Cells to TRAIL-Induced Apoptosis and Enhances Cell-Mediated Cytotoxicity

Mobilization with Cyclophosphamide Shifts Hematopoiesis From the Bone Marrow to the Spleen In Mouse.

Hematopoietic Stem Cells Survive Warm Ischemia and the Bone Marrow Upregulates a Significant Number of Genes

Active Chromatin Structure near MYB Occupancy at the Mir-155 Host Gene Promoter Coincides with Increased Mir-155 and MYB Levels In Chronic Lymphocytic Leukemia

Transplantation Window Created by Bone Marrow Irradiation and Its Closure.

The Oncogenic Mir-17-92 MicroRNA Cluster Is Inhibited by EGR2 During Macrophage Differentiation Via JARID1b-Mediated Histone 3 Lysine 4 Demethylation

ISWI Chromatin Remodeling ATPase Smarca5 (Snf2h) Is Required for Murine Erythroid Development and Globin Gene Regulation

Upregulation of Caspase 10 Contributes to Acquired Resistance of Acute T-Lymphoblastic Leukemia Cells to Proapoptotic Cytokine TRAIL.

Transcription Factors PU.1 and EGR2 Inhibits the Oncogenic Microrna Cluster Mir-17-92 during Macrophage Differentiation

Acquired Resistance to Tumor Necrosis Factor-Related Apoptosis- Inducing Ligand (TRAIL): Histone Deacetylase Inhibitors Resensitize TRAIL-Resistant Jurkat Acute Lymphocytic Leukemia Cells

Proteomic and mRNA Expression Chip Analysis of Acquired TRAIL-Resistance in Human HL60 Myeloid Leukemia Cells.

Genome-Wide and Functional Analysis of Acquired Resistance to TRAIL/APO2l Mediated Apoptosis of Leukemia Cell Lines.

PU.1 Activity Determines Fate of Myeloid Progenitor Cells during Lineage Commitment.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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