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Elisabetta Abruzzese, MD PhD
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Journal Articles

Arterial Occlusive Events (AOEs) in the Phase 2 Ponatinib PACE Trial: 5-Year Update in Heavily Treated Patients (Pts) with Chronic-Phase Chronic Myeloid Leukemia (CP-CML)

Jorge E. Cortes, MD, Franck Emmanuel Nicolini, MD PhD, Andreas Hochhaus, MD, Philipp D. le Coutre, MD, Dong-Wook Kim, MD PhD, Javier Pinilla-Ibarz, MD PhD, Ronald Paquette, MD, Charles Chuah, MD, Jane F. Apperley, FRCP, FRCPath, MD MBChB, Moshe Talpaz, MD, Daniel J. DeAngelo, MD, Elisabetta Abruzzese, MD PhD, Delphine Rea, MD PhD, Martin C. Mueller, MD, Carlo Gambacorti-Passerini, MD, Fausto Castagnetti, MD, Stephanie Lustgarten, PhD, Frank Neumann, MD PhD, Timothy P. Clackson, PhD, Francois Guilhot, MD, Michael W. Deininger, MD PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Neil P. Shah, MD PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2896.
https://doi.org/10.1182/blood.V130.Suppl_1.2896.2896
Published: 2017
Journal Articles

Association between 9p21 Chromosome Polymorphisms rs1333040 and rs7865618 and Chronic Myeloid Leukemia

Federica SORA, MD, Patrizia Chiusolo, Igor Giarretta, Elisabetta Abruzzese, MD PhD, Sara Marietti, Francesco Autore, Ilaria Gatto, Andrea Bacigalupo, MD, Roberto Pola, Simona Sica, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2866.
https://doi.org/10.1182/blood.V130.Suppl_1.2866.2866
Published: 2017
Journal Articles

What's Next in CML - a Prospective Study Evaluating Sanger Sequencing and Next Generation Sequencing (NGS) for BCR-ABL1 Kinase Domain (KD) Mutation Screening

Simona Soverini, PhD, Luana Bavaro, Caterina De Benedittis, PhD, Margherita Martelli, Stefania Stella, PhD, Paolo Vigneri, MD PhD, Alessandra Iurlo, MD PhD, Nicola Orofino, MD, Simona Sica, MD, Federica Sorà, MD, Sara Galimberti, PhD MD, Claudia Baratè, MD PhD, Francesco Albano, MD, Antonella Russo Rossi, MD, Fabio Ciceri, MD, Francesca Lunghi, MD, Fausto Castagnetti, MD, Gabriele Gugliotta, MD PhD, Gianantonio Rosti, MD, Elena Tenti, PhD, Fabio Stagno, MD PhD, Elisabetta Novella, PhD, Eros Di Bona, MD, Massimiliano Bonifacio, MD, Elisabetta Abruzzese, MD PhD, Marzia Salvucci, MD, Mariella D'Adda, MD, Rosaria Sancetta, MD, Elisabetta Calistri, MD, Monica Bocchia, Isabella Capodanno, MD, Giuseppina Spinosa, MD, Maria Antonella Laginestra, PhD, Santa Errichiello, PhD, Anna Serra, Dr, Francesca Carnuccio, Dr, Sabrina Coluzzi, PhD, Mario Annunziata, MD, Caterina Musolino, MD, Fabrizio Pane, MD, Giuseppe Saglio, MD PhD, Michele Baccarani, MD, Michele Cavo, MD, Giovanni Martinelli, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 248.
https://doi.org/10.1182/blood.V130.Suppl_1.248.248
Published: 2017
Journal Articles

Efficacy and Safety of Ponatinib in Chronic Phase-Chronic Myeloid Leukemia (CP-CML) According to the Extent of Treatment with Prior Tyrosine Kinase Inhibitors (TKIs): Final (5-Year) Results of the PACE Study

Andreas Hochhaus, MD, Jorge E. Cortes, MD, Dong-Wook Kim, MD PhD, Javier Pinilla-Ibarz, MD PhD, Philipp D. le Coutre, MD, Ronald Paquette, MD, Charles Chuah, MD, Franck Emmanuel Nicolini, MD PhD, Moshe Talpaz, MD, Daniel J. DeAngelo, MD, Elisabetta Abruzzese, MD PhD, Delphine Rea, MD, Martin C. Mueller, MD, Carlo Gambacorti-Passerini, MD, Fausto Castagnetti, MD PhD, Dragana Milojkovic, MBBS, PhD, Stephanie Lustgarten, PhD, Victor M. Rivera, PhD, Frank Neumann, MD PhD, Francois Guilhot, MD, Michael W. Deininger, MD PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Neil P. Shah, MD PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1617.
https://doi.org/10.1182/blood.V130.Suppl_1.1617.1617
Published: 2017
Journal Articles

Observational Study of CML Italian Patients Who Discontinued TKIs

Carmen Fava, MD PhD, Giovanna Rege-Carmbrin, Irene Dogliotti, Marco Cerrano, Paola Berchialla, Gianantonio Rosti, MD, Fausto Castagnetti, MD PhD, Gabriele Gugliotta, MD PhD, Bruno Martino, Carlo Gambacorti-Passerini, MD, Elisabetta Abruzzese, MD PhD, Ester Maria Orlandi, MD, Chiara Elena, Patrizia Pregno, Antonella Gozzini, MD, Paolo Avanzini, MD, Micaela Bergamaschi, MD, Monica Crugnola, MD, Monica Bocchia, Sara Galimberti, PhD MD, Davide Rapezzi, MD, Alessandra Iurlo, MD PhD, Daniele Cattaneo, MD, Roberto Latagliata, Massimo Breccia, MD, PhD, Michele Cedrone, MD, Marco Santoro, MD, Mario Annunziata, MD, Luciano Levato, MD, Fabio Stagno, MD PhD, Francesco Cavazzini, MD, Nicola Sgherza, Valentina Giai, Luigiana Luciano, Sabina Russo, Pellegrino Musto, MD, Giovanni Caocci, MD, Federica SORA, MD, Francesco Iuliano, Francesca Lunghi, MD, Giorgina Specchia, MD, Fabrizio Pane, MD, Michele Baccarani, MD, Dario Ferrero, Giuseppe Saglio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1616.
https://doi.org/10.1182/blood.V130.Suppl_1.1616.1616
Published: 2017
Journal Articles

Health-Related Quality of Life and Symptom Burden in Chronic Myeloid Leukemia Patients Treated with First Line with Imatinib Versus Those Treated with Dasatinib: First Results of the Leonidas Study

Fabio Efficace, PhD, Michele Baccarani, MD, Fabio Stagno, MD PhD, Alessandra Iurlo, MD PhD, Elisabetta Abruzzese, MD PhD, Luigi Scaffidi, Massimo Breccia, MD, PhD, Fausto Castagnetti, MD PhD, Emilio Usala, MD, Monica Crugnola, MD, Isabella Capodanno, Bruno Martino, Mario Tiribelli, MD, Gianluca Gaidano, MD PhD, Alberto Bosi, MD, Luigia Luciano, MD, Patrizia Pregno, Francesco Cottone, Patrizia Tosi, MD, Nicola Cascavilla, MD, Gianni Binotto, Susanne Saussele, MD, Claudio Fozza, Micaela Bergamaschi, MD, Rosaria Sancetta, MD, Giovanni Caocci, MD, Gianantonio Rosti, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3422.
https://doi.org/10.1182/blood.V130.Suppl_1.3422.3422
Published: 2017
Journal Articles

Clinical Impact Of Dose Modification On Response To Ponatinib In Patients With Chronic Phase Chronic Myeloid Leukemia (CP-CML)

Javier Pinilla-Ibarz, MD, PhD, Jorge E. Cortes, MD, Dong-Wook Kim, MD, PhD, Philipp D. Le Coutre, MD, Ronald Paquette, MD, Charles Chuah, MD, Franck E. Nicolini, MD, PhD, Jane F Apperley, MD, H. Jean Khoury, MD, John F. Dipersio, MD, PhD, Daniel J DeAngelo, MD, PhD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, MD, Martin C Muller, MD, Carlo Gambacorti-Passerini, MD, Stephanie Lustgarten, PhD, Victor M. Rivera, PhD, Tim Clackson, PhD, Christopher D Turner, MD, Frank G Haluska, MD, PhD, Francois Guilhot, MD, Michael W. Deininger, MD, PhD, Andreas Hochhaus, MD, Timothy P. Hughes, MD, MBBS, John M Goldman, DM, Neil P. Shah, MD, PhD, Hagop M. Kantarjian, MD, Moshe Talpaz, MD
Journal: Blood
Blood (2013) 122 (21): 4007.
https://doi.org/10.1182/blood.V122.21.4007.4007
Published: 2013
Journal Articles

Efficacy and Safety Of Ponatinib Following Failure Of Nilotinib In Patients With Chronic Phase Chronic Myeloid Leukemia (CP-CML) In The PACE Trial

Hagop M. Kantarjian, MD, Jorge E. Cortes, MD, Dong-Wook Kim, MD, PhD, Javier Pinilla-Ibarz, MD, PhD, Philipp D. le Coutre, MD, Ronald Paquette, MD, Charles Chuah, MD, Franck E. Nicolini, MD, PhD, Jane F. Apperley, MD, H Jean Khoury, MD, Moshe Talpaz, MD, John F. DiPersio, MD, PhD, Daniel J. DeAngelo, MD, PhD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, MD, Martin C. Müller, MD, Carlo Gambacorti-Passerini, MD, Stephanie Lustgarten, PhD, Victor M. Rivera, PhD, Tim Clackson, PhD, Christopher D. Turner, MD, Frank G. Haluska, MD, PhD, Francois Guilhot, MD, Michael W. Deininger, Andreas Hochhaus, MD, Timothy P. Hughes, MD, MBBS, John M. Goldman, MD, Neil P. Shah, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2738.
https://doi.org/10.1182/blood.V122.21.2738.2738
Published: 2013
Journal Articles

The e13a2 BCR-ABL1 Fusion Transcript Is a Candidate Adverse Prognostic Factor In Chronic Myeloid Leukemia Patients Treated Frontline With Imatinib Mesylate

Fausto Castagnetti, Gabriele Gugliotta, Massimo Breccia, Alessandra Iurlo, MD, Elisabetta Abruzzese, MD, PhD, Francesco Albano, Paolo G Vigneri, MD/PhD, Francesco Cavazzini, Ester Orlandi, MD, Patrizia Pregno, MD, Mario Annunziata, MD, Piero Galieni, MD, Enrico Montefusco, Carmen Fava, MD, Francesca Palandri, Claudia Venturi, Simona Soverini, Nicoletta Testoni, BS, Giuliana Alimena, Giuseppe Saglio, Fabrizio Pane, MD, Giovanni Martinelli, MD, Michele Cavo, MD, Michele Baccarani, MD, Gianantonio Rosti
Journal: Blood
Blood (2013) 122 (21): 1486.
https://doi.org/10.1182/blood.V122.21.1486.1486
Published: 2013
Journal Articles

Ponatinib In Heavily Pretreated Patients With Chronic Phase Chronic Myeloid Leukemia (CP-CML): Management Of Adverse Events (AEs)

Philipp D. Le Coutre, MD, Dong-Wook Kim, MD, PhD, Javier Pinilla-Ibarz, MD, PhD, Ronald Paquette, MD, Charles Chuah, MD, Franck E. Nicolini, MD, PhD, Jane F Apperley, MD, H. Jean Khoury, MD, Moshe Talpaz, MD, John F. Dipersio, MD, PhD, Daniel J DeAngelo, MD, PhD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, MD, Martin C Muller, MD, Carlo Gambacorti-Passerini, MD, Stephanie Lustgarten, PhD, Kumiko Yanase, MD, PhD, Christopher D Turner, MD, Frank G Haluska, MD, PhD, Francois Guilhot, MD, Michael W. Deininger, MD, PhD, Andreas Hochhaus, MD, Timothy P. Hughes, MD, MBBS, John M Goldman, DM, Neil P. Shah, MD, PhD, Hagop M. Kantarjian, MD, Jorge E. Cortes, MD
Journal: Blood
Blood (2013) 122 (21): 1496.
https://doi.org/10.1182/blood.V122.21.1496.1496
Published: 2013
Journal Articles

Efficacy and Safety Of Ponatinib Following Failure Of Dasatinib In Patients (pts) With Chronic Phase Chronic Myeloid Leukemia (CP-CML) In The PACE Trial

Andreas Hochhaus, MD, Jorge E. Cortes, MD, Dong-Wook Kim, MD, PhD, Javier Pinilla-Ibarz, MD, PhD, Philipp D le Coutre, MD, Ronald Paquette, MD, Charles Chuah, MD, Franck E. Nicolini, MD, PhD, Jane F Apperley, MD, H. Jean Khoury, MD, Moshe Talpaz, MD, John F. DiPersio, MD, PhD, Daniel J DeAngelo, MD, PhD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, MD, Martin C. Müller, MD, Carlo Gambacorti-Passerini, MD, Stephanie Lustgarten, PhD, Victor M. Rivera, PhD, Tim Clackson, PhD, Christopher D Turner, MD, Frank G Haluska, MD, PhD, Michael W. Deininger, MD, PhD, Timothy P. Hughes, MD, MBBS, John M Goldman, MD, Neil P. Shah, MD, PhD, Hagop M. Kantarjian, MD, François Guilhot, MD
Journal: Blood
Blood (2013) 122 (21): 1498.
https://doi.org/10.1182/blood.V122.21.1498.1498
Published: 2013
Journal Articles

Ponatinib In Patients (pts) With Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) Resistant Or Intolerant To Dasatinib Or Nilotinib, Or With The T315I BCR-ABL Mutation: 2-Year Follow-Up Of The PACE Trial

Jorge E. Cortes, MD, Dong-Wook Kim, MD, PhD, Javier Pinilla-Ibarz, MD, PhD, Philipp D le Coutre, MD, Ronald Paquette, MD, Charles Chuah, MD, Franck E. Nicolini, MD PhD, Jane F Apperley, MD, H. Jean Khoury, MD, Moshe Talpaz, MD, John F. DiPersio, MD, PhD, Daniel J DeAngelo, MD, PhD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, MD, Martin C. Müller, MD, Carlo Gambacorti-Passerini, MD, Stephanie Lustgarten, PhD, Victor M. Rivera, PhD, Tim Clackson, PhD, Christopher D Turner, MD, Frank G Haluska, MD, PhD, François Guilhot, MD, Michael W. Deininger, MD, PhD, Andreas Hochhaus, MD, Timothy P. Hughes, MD, MBBS, John M Goldman, MD, Neil P. Shah, MD, PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2013) 122 (21): 650.
https://doi.org/10.1182/blood.V122.21.650.650
Published: 2013
Journal Articles

Frontline Treatment With Imatinib Mesylate in Chronic Myeloid Leukemia Patients in Early Chronic Phase: a Very Long-Term Analysis by the GIMEMA CML Working Party

Fausto Castagnetti, Gabriele Gugliotta, Massimo Breccia, Giorgina Specchia, Tamara Intermesoli, Adele Capucci, Bruno Martino, MD, Mario Tiribelli, MD, Gianni Binotto, MD, Elisabetta Abruzzese, MD, PhD, Fabio Stagno, MD, Pietro Leoni, MD, Dario Ferrero, MD, Filippo Gherlinzoni, MD, Francesca Palandri, Claudia Venturi, Maria Teresa Bochicchio, Simona Soverini, Giuliana Alimena, MD, Giovanni Martinelli, Fabrizio Pane, MD, Giuseppe Saglio, MD, Michele Cavo, MD, Michele Baccarani, MD, Gianantonio Rosti
Journal: Blood
Blood (2013) 122 (21): 258.
https://doi.org/10.1182/blood.V122.21.258.258
Published: 2013
Journal Articles

Efficacy and Safety of Ponatinib According to Prior Approved Tyrosine Kinase Inhibitor (TKI) Therapy in Patients with Chronic Myeloid Leukemia in Chronic Phase (CP-CML): Results From the PACE Trial

Dong-Wook Kim, Jorge E. Cortes, MD, Javier Pinilla-Ibarz, MD, PhD, Philipp le Coutre, MD, Ronald Paquette, MD, PhD, Charles Chuah, MD, Franck E. Nicolini, MD, PhD, Jane Apperley, H. Jean Khoury, Moshe Talpaz, MD, John F. DiPersio, MD, PhD, Daniel DeAngelo, MD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, MD, Martin C Muller, MD, Carlo Gambacorti-Passerini, MD, Stephane Wong, PhD, Stephanie Lustgarten, Victor M. Rivera, PhD, Tim Clackson, PhD, Christopher D. Turner, MD, FAAP, Frank G Haluska, MD, PhD, Francois Guilhot, Michael W. Deininger, MD, PhD, Andreas Hochhaus, MD, Timothy P. Hughes, MD, MBBS, John M Goldman, MD, Neil Shah, MD, PhD, Hagop M. Kantarjian, MD, The PACE Study Group
Journal: Blood
Blood (2012) 120 (21): 3749.
https://doi.org/10.1182/blood.V120.21.3749.3749
Published: 2012
Journal Articles

Molecular Responses with Ponatinib in Patients with Philadelphia Chromosome Positive (Ph+) Leukemia: Results From the PACE Trial

Andreas Hochhaus, MD, Dong-Wook Kim, Javier Pinilla-Ibarz, MD, PhD, Philipp le Coutre, MD, Ronald Paquette, MD, PhD, Charles Chuah, MD, Franck E. Nicolini, MD, PhD, Jane Apperley, H. Jean Khoury, MD, Moshe Talpaz, MD, John F. DiPersio, MD, PhD, Daniel DeAngelo, MD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, Martin C Muller, MD, Carlo Gambacorti-Passerini, Stephane Wong, PhD, Stephanie Lustgarten, Victor M. Rivera, PhD, Tim Clackson, PhD, Christopher D. Turner, MD, FAAP, Frank G Haluska, MD, PhD, Francois Guilhot, Michael W. Deininger, MD, PhD, Timothy P. Hughes, MD, MBBS, John M Goldman, MD, Neil Shah, MD, PhD, Hagop M. Kantarjian, MD, Jorge E. Cortes, MD, The PACE Study Group
Journal: Blood
Blood (2012) 120 (21): 3763.
https://doi.org/10.1182/blood.V120.21.3763.3763
Published: 2012
Journal Articles

Efficacy and Safety of Ponatinib in Patients with Accelerated Phase or Blast Phase Chronic Myeloid Leukemia (AP-CML or BP-CML) or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL): 12-Month Follow-up of the PACE Trial

Hagop M. Kantarjian, MD, Dong-Wook Kim, Javier Pinilla-Ibarz, MD, PhD, Philipp le Coutre, MD, Ronald Paquette, MD, PhD, Charles Chuah, MD, Franck E. Nicolini, MD, PhD, Jane Apperley, H. Jean Khoury, MD, Moshe Talpaz, MD, John F. DiPersio, MD, PhD, Daniel DeAngelo, MD, Elisabetta Abruzzese, MD, PhD, Delphine Rea, MD, PhD, Michele Baccarani, MD, Martin C Muller, MD, Carlo Gambacorti-Passerini, MD, Stephane Wong, PhD, Stephanie Lustgarten, Victor M. Rivera, PhD, Tim Clackson, PhD, Christopher D. Turner, MD, FAAP, Frank G Haluska, MD, PhD, Francois Guilhot, Michael W. Deininger, MD, PhD, Andreas Hochhaus, MD, Timothy P. Hughes, MD, MBBS, John Goldman, DM, FRCP, FRCPath, FMedSci, Neil Shah, MD, PhD, Jorge E. Cortes, MD, The PACE Study Group
Journal: Blood
Blood (2012) 120 (21): 915.
https://doi.org/10.1182/blood.V120.21.915.915
Published: 2012