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Journal Articles

A Dynamic Epigenetic Landscape in Genetic and Immunophenotypic Stable Pediatric AML

Diana Hanekamp, MSc, Jennifer R. Scheick, Yaseswini Neelamraju, Edwin Sonneveld, PhD, Valerie de Haas, MD PhD, Gert J. Ossenkoppele, MD PhD, Gerrit J. Schuurhuis, PhD, Gertjan J.L. Kaspers, MD PhD, Francine E. Garrett-Bakelman, MDPhD, Jacqueline Cloos, PhD

Blood (2017) 130 (Supplement 1): 2686.

https://doi.org/10.1182/blood.V130.Suppl_1.2686.2686

Published: 2017

Journal Articles

NUP98-KDM5A Fusion Gene Is Not Exclusive to Acute Megakaryoblastic Leukemia and Is an Independent Predictor of Poor Prognosis

Sanne Noort, MD MSc, Robert B Gerbing, Todd A Alonzo, PhD, Jenny L. Smith, MSc, MD, Edwin Sonneveld, PhD, Franco Locatelli, MD PhD, Dirk Reinhardt, MD, Andre Baruchel, MD, Jan Stary, Marry M. Van den Heuvel-Eibrink, MD, C. Michel Zwaan, Soheil Meshinchi, MD PhD

Blood (2017) 130 (Supplement 1): 3934.

https://doi.org/10.1182/blood.V130.Suppl_1.3934.3934

Published: 2017

Journal Articles

Distinct Outcome Based on Fusion Transcript in t(16;21) Rearranged Pediatric AML, a Collaborative Retrospective Analysis By the I-BFM SG

Blood (2017) 130 (Supplement 1): 184.

https://doi.org/10.1182/blood.V130.Suppl_1.184.184

Published: 2017

Journal Articles

Genomic Architecture and Clonal Dynamics of Early Relapsed BCP-ALL

Zeljko Antic, MD, Jiangyan Yu, MSc, Simon V. van Reijmersdal, Renske Kuiper, Edwin Sonneveld, PhD, Frank N. van Leeuwen, PhD, Peter M. Hoogerbrugge, MD PhD, Esmé Waanders, PhD, Roland P. Kuiper, PhD

Blood (2016) 128 (22): 4072.

https://doi.org/10.1182/blood.V128.22.4072.4072

Published: 2016

Journal Articles

Genetic Architecture of Relapsed Pediatric B Cell Precursor Acute Lymphoblastic Leukemia Are Related to the Intensity of Upfront Therapy

Jiangyan Yu, MSc, Esmé Waanders, PhD, Simon V. van Reijmersdal, Edwin Sonneveld, PhD, Frank N. van Leeuwen, PhD, Rob Pieters, MD PhD, Ad Geurts van Kessel, PhD, Peter M. Hoogerbrugge, MD PhD, Roland P. Kuiper, PhD

Blood (2015) 126 (23): 247.

https://doi.org/10.1182/blood.V126.23.247.247

Published: 2015

Journal Articles

Prognostic Relevance of Recurrent Genetic Aberrations in Pediatric Acute Megakaryoblastic Leukemia

Jasmijn de Rooij, MD, Riccardo Masetti, MD, Marry M. van den Heuvel-Eibrink, MD PhD, Jean-Michel Cayuela, Jan Trka, Dirk Reinhardt, MD, Edwin Sonneveld, PhD, Todd A. Alonzo, PhD, Maarten Fornerod, Martin Zimmermann, Martina Pigazzi, PhD, Rob Pieters, MD PhD, Soheil Meshinchi, MD PhD, C. Michel Zwaan, Franco Locatelli

Blood (2015) 126 (23): 2598.

https://doi.org/10.1182/blood.V126.23.2598.2598

Published: 2015

Journal Articles

Accurate Detection of Low Mosaic Mutations Associated with Therapy Resistance in Pediatric Acute Lymphoblastic Leukemia Using Single Molecule Tagging and Deep-Sequencing

Jiangyan Yu, MSc, Simon V. van Reijmersdal, Alexander Hoischen, PhD, Edwin Sonneveld, PhD, Peter M. Hoogerbrugge, MD PhD, Esmé Waanders, PhD, Roland P. Kuiper, PhD

Blood (2015) 126 (23): 2608.

https://doi.org/10.1182/blood.V126.23.2608.2608

Published: 2015

Journal Articles

Targeted Locus Amplification & Next Generation Sequencing for the Detection of Recurrent and Novel Gene Fusions for Improved Treatment Decisions in Pediatric Acute Lymphoblastic Leukemia

Roland P. Kuiper, PhD, Simon V. van Reijmersdal, Marieke Simonis, PhD, Jiangyan Yu, MSc, Edwin Sonneveld, PhD, Blanca Scheijen, PhD, Judith M. Boer, PhD, Aurélie Boeree, BSc, Petra Klous, MSc, Peter M Hoogerbrugge, MD PhD, Mehmet Yilmaz, MSc, Frank N. van Leeuwen, PhD, Monique L. Den Boer, PhD, Erik Splinter, PhD

Blood (2015) 126 (23): 696.

https://doi.org/10.1182/blood.V126.23.696.696

Published: 2015

Journal Articles

Spliceosome Inhibitor Meayamycin B As a Novel Potential Chemotherapeutic Agent in ALL and AML

Anna Wojtuszkiewicz, MSc, Yehuda G Assaraf, PhD, Gerrit Jansen, PhD, Kazunori Koide, PhD, Robert K. Bressin, Upamanyu Basu, Edwin Sonneveld, PhD, Elisa Giovannetti, PhD, Gertjan Kaspers, MD PhD, Jacqueline Cloos, PhD

Blood (2014) 124 (21): 924.

https://doi.org/10.1182/blood.V124.21.924.924

Published: 2014

Journal Articles

Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study

Blood (2014) 124 (21): 368.

https://doi.org/10.1182/blood.V124.21.368.368

Published: 2014

Journal Articles

Genetic Aberrations As Putative MRD Targets in Childhood Acute Myeloid Leukaemia

Edwin Sonneveld, PhD, Valerie De Haas, Gertjan Kaspers, MD PhD, C. Michel Zwaan, Eveline Bont, MD PhD, Vincent van der Velden, PhD

Blood (2014) 124 (21): 2331.

https://doi.org/10.1182/blood.V124.21.2331.2331

Published: 2014

Journal Articles

IKZF1 deletions in Pediatric Acute Myeloid Leukemia

Jasmijn de Rooij, MD, Eva Beuling, PhD, C. Michel Zwaan, Askar Obulkasim, André Baruchel, MD, Jan Trka, MD PhD, Dirk Reinhardt, MD PhD, Edwin Sonneveld, PhD, Brenda Gibson, Martin Zimmermann, Rob Pieters, MD PhD, Marry van den Heuvel-Eibrink, MD PhD, Maarten Fornerod, PhD

Blood (2014) 124 (21): 2346.

https://doi.org/10.1182/blood.V124.21.2346.2346

Published: 2014

Journal Articles

Paired Analyses of Diagnostic and Relapse Samples of MLL rearranged Infant Acute Lymphoblastic Leukemia Reveals Potential Therapy-Resistant Genomic Alterations

Arjan Buijs, PhD, Marian JPL Stevens-Kroef, PhD, Edwin Sonneveld, PhD, Lars T. van der Veken, PhD

Blood (2014) 124 (21): 5345.

https://doi.org/10.1182/blood.V124.21.5345.5345

Published: 2014

Journal Articles

ETV6 Aberrations Are a Recurrent Event in Pediatric Acute Myeloid Leukemia with Poor Clinical Outcome

Jasmijn de Rooij, MD, Eva Beuling, PhD, Maarten Fornerod, PhD, Askar Obulkasim, André Baruchel, MD, Jan Trka, MD, PhD, Prof., Dirk Reinhardt, MD PhD, Edwin Sonneveld, PhD, Martin Zimmermann, Rob Pieters, MD PhD, Marry van den Heuvel-Eibrink, MD PhD, C. Michel Zwaan, MD PhD

Blood (2014) 124 (21): 1012.

https://doi.org/10.1182/blood.V124.21.1012.1012

Published: 2014

Journal Articles

Microrna-106b~25 Cluster Is Involved in Relapsed MLL -Rearranged Pediatric AML

Lonneke Verboon, Maarten Fornerod, PhD, Askar Obulkasim, Edwin Sonneveld, PhD, André Baruchel, MD, Jan Trka, MD PhD, Dirk Reinhardt, MD PhD, Rob Pieters, MD PhD, Jacqueline Cloos, PhD, Gertjan JL Kaspers, MD PhD, Jan-Henning Klusmann, MD, C. Michel Zwaan, MD PhD, Marry van den Heuvel-Eibrink, MD PhD

Blood (2014) 124 (21): 1038.

https://doi.org/10.1182/blood.V124.21.1038.1038

Published: 2014

Journal Articles

The Majority of RAS Pathway Mutations Detected in Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Are Present in Major or Minor Subclones at Diagnosis

Jiangyan Yu, Esmé Waanders, PhD, Simon V. van Reijmersdal, Edwin Sonneveld, PhD, Peter M Hoogerbrugge, MD PhD, Frank N. van Leeuwen, PhD, Ad Geurts van Kessel, PhD, Roland P. Kuiper, PhD

Blood (2014) 124 (21): 2397.

https://doi.org/10.1182/blood.V124.21.2397.2397

Published: 2014

Journal Articles

Immunophenotyping Versus Morphological Evaluation Of Fresh and Stabilized Cerebrospinal Fluid As Diagnostic Tool For CNS Involvement In Childhood Acute Lymphoblastic Leukemia

Edwin Sonneveld, PhD, Christian M. Zwaan, MD, PhD, Alita J van der Sluijs-Gelling, Valerie de Haas, MD, PhD, Rob Pieters, Vincent H.J. van der Velden, PhD

Blood (2013) 122 (21): 4950.

https://doi.org/10.1182/blood.V122.21.4950.4950

Published: 2013

Journal Articles

B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Specific Copy Number Alterations Are Unique For Progressive Pediatric Chronic Myeloid Leukemia (CML): A Large Cohort Study

Naomi E van der Sligte, Manuela Krumbholz, PhD, Agata Pastorczak, MD, Blanca Scheijen, PhD, Josephine T. Tauer, Christina Nowasz, Edwin Sonneveld, PhD, Truuske H. de Bock, PhD, Tiny G. Meeuwsen - de Boer, BSc, Simon V. van Reijmersdal, BSc, Roland P. Kuiper, PhD, Jutta Bradtke, PhD, Markus Metzler, MD, Meinolf Suttorp, Evelina S. De Bont, Frank N. van Leeuwen, PhD

Blood (2013) 122 (21): 2715.

https://doi.org/10.1182/blood.V122.21.2715.2715

Published: 2013

Journal Articles

Leukemia Cells with a BCR-ABL1-Like signature and/or IKZF1 deletions, but Not High CRLF2 Expression, Are Predictive of an Unfavorable Prognosis in Childhood B Cell Precursor Acute Lymphoblastic Leukemia

Arian Van Der Veer, Esmee Waanders, PhD, Rob Pieters, MD, PhD, Marieke E. Willemse, Simon Reijmersdaal, Lisa J Russell, PhD, Christine J Harrison, PhD, FRCPath, William E. Evans, PharmD, Vincent H.J. van der Velden, PhD, Peter M. Hoogerbrugge, Frank N. van Leeuwen, PhD, G. Escherich, Martin Horstman, Leila mohammadi Khankahdani, Dimitris Rizopoulos, Hester A. de Groot-Kruseman, PhD, Edwin Sonneveld, PhD, Roland P. Kuiper, PhD, Monique L. Den Boer, PhD

Blood (2012) 120 (21): 880.

https://doi.org/10.1182/blood.V120.21.880.880

Published: 2012

Journal Articles

NUP98/JARID1A Is a New Recurrent Genetic Abnormality in Pediatric Acute Megakaryoblastic Leukemia with a Distinct HOX -Gene Expression Pattern

Jasmijn D.E. de Rooij, MD, Marry M. van den Heuvel-Eibrink, Iris H.I.M. Hollink, MD, PhD, Susan T.C.J.M. Arentsen-Peters, H. Berna Beverloo, PhD, Janneke F. van Galen, Andre Baruchel, MD, PhD, Jan Trka, MD, PhD, Dirk Reinhardt, MD, Edwin Sonneveld, PhD, Martin Zimmermann, Todd A. Alonzo, PhD, Rob Pieters, MD, PhD, Soheil Meshinchi, MD, PhD, C. Michel Zwaan, MD, PhD

Blood (2012) 120 (21): 537.

https://doi.org/10.1182/blood.V120.21.537.537

Published: 2012

NARROW

A Dynamic Epigenetic Landscape in Genetic and Immunophenotypic Stable Pediatric AML

NUP98-KDM5A Fusion Gene Is Not Exclusive to Acute Megakaryoblastic Leukemia and Is an Independent Predictor of Poor Prognosis

Distinct Outcome Based on Fusion Transcript in t(16;21) Rearranged Pediatric AML, a Collaborative Retrospective Analysis By the I-BFM SG

Genomic Architecture and Clonal Dynamics of Early Relapsed BCP-ALL

Genetic Architecture of Relapsed Pediatric B Cell Precursor Acute Lymphoblastic Leukemia Are Related to the Intensity of Upfront Therapy

Prognostic Relevance of Recurrent Genetic Aberrations in Pediatric Acute Megakaryoblastic Leukemia

Accurate Detection of Low Mosaic Mutations Associated with Therapy Resistance in Pediatric Acute Lymphoblastic Leukemia Using Single Molecule Tagging and Deep-Sequencing

Targeted Locus Amplification & Next Generation Sequencing for the Detection of Recurrent and Novel Gene Fusions for Improved Treatment Decisions in Pediatric Acute Lymphoblastic Leukemia

Spliceosome Inhibitor Meayamycin B As a Novel Potential Chemotherapeutic Agent in ALL and AML

Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study

Genetic Aberrations As Putative MRD Targets in Childhood Acute Myeloid Leukaemia

IKZF1 deletions in Pediatric Acute Myeloid Leukemia

Paired Analyses of Diagnostic and Relapse Samples of MLL rearranged Infant Acute Lymphoblastic Leukemia Reveals Potential Therapy-Resistant Genomic Alterations

ETV6 Aberrations Are a Recurrent Event in Pediatric Acute Myeloid Leukemia with Poor Clinical Outcome

Microrna-106b~25 Cluster Is Involved in Relapsed MLL -Rearranged Pediatric AML

The Majority of RAS Pathway Mutations Detected in Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Are Present in Major or Minor Subclones at Diagnosis

Immunophenotyping Versus Morphological Evaluation Of Fresh and Stabilized Cerebrospinal Fluid As Diagnostic Tool For CNS Involvement In Childhood Acute Lymphoblastic Leukemia

B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Specific Copy Number Alterations Are Unique For Progressive Pediatric Chronic Myeloid Leukemia (CML): A Large Cohort Study

Leukemia Cells with a BCR-ABL1-Like signature and/or IKZF1 deletions, but Not High CRLF2 Expression, Are Predictive of an Unfavorable Prognosis in Childhood B Cell Precursor Acute Lymphoblastic Leukemia

NUP98/JARID1A Is a New Recurrent Genetic Abnormality in Pediatric Acute Megakaryoblastic Leukemia with a Distinct HOX -Gene Expression Pattern

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American Society of Hematology

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ASH Publications

American Society of Hematology

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