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Dorothee Leroux
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Journal Articles

Increased risk of thrombosis in FcγRIIA 131RR patients with HIT due to defective control of platelet activation by plasma IgG2

Clinical Trials & Observations
Jérôme Rollin, Claire Pouplard, Hsueh Cheng Sung, Dorothée Leroux, Armand Saada, Valérie Gouilleux-Gruart, Gilles Thibault, Yves Gruel
Journal: Blood
Blood (2015) 125 (15): 2397–2404.
https://doi.org/10.1182/blood-2014-09-594515
Published: 2015
Includes: Supplemental data
Journal Articles

Influence of FcγRIIA H131R Polymorphism on the Risk of Thrombosis in HIT and Variable Effect of Normal IgG on Platelet Activation

Jerôme Rollin, PhD, Claire Pouplard, Dorothee Leroux, Armand Saada, Céline Behier, Valérie Gouilleux Gruart, Gilles Thibault, PharmD, Yves Gruel, MD PhD
Journal: Blood
Blood (2014) 124 (21): 234.
https://doi.org/10.1182/blood.V124.21.234.234
Published: 2014
Journal Articles

Prospective Evaluation of a Rapid Nanoparticle-Based Lateral Flow Immunoassay (Stic Expert HIT ® ) for the Diagnosis of Heparin-Induced Thrombocytopenia

Claire Pouplard, PharmD, PhD, Dorothee Leroux, PharmD, Nathalie Hezard, MD, PhD, Aurelien Lebreton, MD, Anne Bauters, MD, William Cohen, Emmanuel De Maistre, MD, Isabelle Diaz, Pharm D, Marie-Genevieve Huisse, Catherine Ternisien, MD, Sophie Voisin, MD, Yves Gruel, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1087.
https://doi.org/10.1182/blood.V120.21.1087.1087
Published: 2012
Journal Articles

Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia

Jérôme Rollin, Claire Pouplard, Marie-Pierre Gratacap, Dorothée Leroux, Marc-Antoine May, Michel Aupart, Valérie Gouilleux-Gruart, Bernard Payrastre, Yves Gruel
Journal: Blood
Blood (2012) 120 (6): 1309–1316.
https://doi.org/10.1182/blood-2012-04-424044
Published: 2012
Includes: Supplemental data
Journal Articles

Incidence of Antibodies to Protamine/Heparin Complexes in Cardiac Surgery Patients and Impact on Platelet Activation in Vitro and Clinical Outcome

Claire Pouplard, PharmD, PhD, Dorothee Leroux, PharmD, Jerôme Rollin, PhD, Amiral Jean, PhD, May Marc Antoine, MD, Aupart Michel, MD, Yves Gruel, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2217.
https://doi.org/10.1182/blood.V118.21.2217.2217
Published: 2011
Journal Articles

Interleukin-10 Promoter Microsatellite Polymorphisms Influence the Immune Response to Heparin and the risk of Heparin-Induced Thrombocytopenia.

Claire Pouplard, PharmD, PhD, Pascale Cornillet-Lefebvre, PharmD, PhD, Redha Attaoua, PharmD, PhD, Dorothee Leroux, PharmD, Florin Grigorescu, MD, PhD, Carinne Lecoq-Lafon, Jerôme Rollin, PhD, Philippe Nguyen, MD, PhD, Yves Gruel, MD
Journal: Blood
Blood (2010) 116 (21): 3682.
https://doi.org/10.1182/blood.V116.21.3682.3682
Published: 2010
Journal Articles

Influence of Protein Tyrosine Phosphatase Polymorphisms on the Development of Antibodies to Platelet Factor 4 and the Risk of Heparin-Induced Thrombocytopenia.

Jerôme Rollin, PhD, Claire Pouplard, PharmD, PhD, Dorothee Leroux, PharmD, Marc-Antoine May, MD, Yves Gruel, MD
Journal: Blood
Blood (2010) 116 (21): 3683.
https://doi.org/10.1182/blood.V116.21.3683.3683
Published: 2010
Journal Articles

Polymorphisms in TNFA and CTLA-4 Genes and the Risk of Heparin Induced Thrombocytopenia.

Dorothee Leroux, Claire Pouplard, PharmD, PhD, Benoit Guillet, MD, PhD, Beatrice Cosne, Marc Antoine May, MD, Yves Gruel, MD
Journal: Blood
Blood (2008) 112 (11): 3414.
https://doi.org/10.1182/blood.V112.11.3414.3414
Published: 2008