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Dixie-Lee Esseltine, MD,FRCPC
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Journal Articles

Quantifying The Risk Of Heart Failure Associated With Proteasome Inhibition: A Retrospective Analysis Of Heart Failure Reported In Phase 2 and Phase 3 Studies Of Bortezomib (Btz) In Multiple Myeloma (MM)

Jacob P. Laubach, MD, Jesús F San Miguel, MD, Pieter Sonneveld, MD, Ph.D, Robert Z. Orlowski, M.D., Ph.D., Philippe Moreau, MD, Laura Rosiñol, MD, Javid J Moslehi, MD, Edward A Faber, Jr., DO, MS, Peter M Voorhees, Loreta Marquez, MD, Avinash Desai, MD, Helgi van de Velde, Jennifer Elliott, Ph.D, Hongliang Shi, Ph.D, Edward Dow, MD, Nishith Jobanputra, DO, Dixie-Lee Esseltine, MD, FRCPC, Liviu Niculescu, MD, Kenneth C. Anderson, MD, Sagar Lonial, M.D., Paul G. Richardson, MD
Journal: Blood
Blood (2013) 122 (21): 3187.
https://doi.org/10.1182/blood.V122.21.3187.3187
Published: 2013
Journal Articles

Identification of Patient Subgroups Demonstrating Longer Progression-Free Survival (PFS) Benefit with Bortezomib-Rituximab Versus Rituximab in Patients with Relapsed or Refractory Follicular Lymphoma (FL): Biomarker Analyses of the Phase 3 LYM3001 Study

Bertrand Coiffier, MD, Weimin Li, Erin D Henitz, BS, J. D. Karkera, PhD, Reyna Favis, PhD, Dana Gaffney, MS, Alice Shapiro, MS, Panteli Theocharous, BSc (hons), MSc, PhD, Yusri A Elsayed, MD, PhD, Helgi van de Velde, MD, PhD, Evgenii A Osmanov, MD, PhD, Xiaonan Hong, MD, Adriana Scheliga, MD, Fritz C. Offner, MD, PhD, Simon Rule, Adriana C Teixeira, MD, Jan Walewski, MD, PhD, Sven de Vos, MD, PhD, Michael Crump, MD, FRCPC, Ofer Shpilberg, MD, MPH, Pier Luigi Zinzani, MD, PhD, Andrew Z Cakana, MD, FRCPath, Dixie-Lee Esseltine, MD, FRCPC, George Mulligan, PhD, Deborah S Ricci, PhD
Journal: Blood
Blood (2011) 118 (21): 265.
https://doi.org/10.1182/blood.V118.21.265.265
Published: 2011
Journal Articles

Mutational Analysis of Tumor Samples From Patients with Relapsed or Refractory Multiple Myeloma (MM) Highlights the Prevalence of RAS/RAF Pathway Activation and Demonstrates Previously Unreported Mutations in Known Cancer Genes

George Mulligan, PhD, David I Lichter, MS, Alessandra Di Bacco, PhD, Stephen J Blakemore, PhD, Allison Berger, PhD, Erik Koenig, Hugues Bernard, William L. Trepicchio, PhD, Bin Li, PhD, Sagar Lonial, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Pieter Sonneveld, MD, PhD, Jesús F San Miguel, MD PhD, Dixie-Lee Esseltine, MD, FRCPC, Matthew Schu, MS
Journal: Blood
Blood (2011) 118 (21): 1377.
https://doi.org/10.1182/blood.V118.21.1377.1377
Published: 2011
Journal Articles

Risk of Second Primary Malignancies (SPMs) Following Bortezomib (Btz)-Based Therapy: Analysis of Four Phase 3 Randomized Controlled Trials in Previously Untreated or Relapsed Multiple Myeloma (MM)

Jesús F San Miguel, MD PhD, Paul G. Richardson, MD, Robert Z. Orlowski, MD, PhD, Hartmut Goldschmidt, Deyanira Corzo, MD, Carol Satler, Dixie-Lee Esseltine, MD, FRCPC, Rachel Neuwirth, MS, Maria Ponsillo, MD, Andrew Z Cakana, MD, FRCPath, Jay King, MD, William M Deraedt, PhD, Avinash Desai, Yana Lutska, Dina Gifkins, PhD, Kevin Liu, PhD, Pieter Sonneveld, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2933.
https://doi.org/10.1182/blood.V118.21.2933.2933
Published: 2011
Journal Articles

Pharmacokinetics (PK) and Pharmacodynamics (PD) of Subcutaneous Versus Intravenous Administration of Bortezomib in Patients with Relapsed Multiple Myeloma: Effects of Subcutaneous Injection Site and Concentration, and Patient Characteristics

Philippe Moreau, MD, Ievgenii I Karamanesht, MD, Natalia Domnikova, Maryna Y Kyselyova, MD, Kateryna Vilchevska, Vadim A Doronin, MD, PhD, Alexander Schmidt, MD, Cyrille Hulin, MD, Xavier Leleu, MD, PhD, Dixie-Lee Esseltine, MD, FRCPC, Karthik Venkatakrishnan, Donna M Skee, BS, Huaibao Feng, PhD, Suzette Girgis, Andrew Z Cakana, MD, FRCPath, William M Deraedt, PhD, Thierry Facon, MD
Journal: Blood
Blood (2011) 118 (21): 1863.
https://doi.org/10.1182/blood.V118.21.1863.1863
Published: 2011
Journal Articles

Continued Overall Survival Benefit After 5 Years' Follow-up with Bortezomib-Melphalan-Prednisone (VMP) Versus Melphalan-Prednisone (MP) in Patients with Previously Untreated Multiple Myeloma, and No Increased Risk of Second Primary Malignancies: Final Results of the Phase 3 VISTA Trial

Jesús F San Miguel, MD PhD, Rudolf Schlag, MD, Nuriet K Khuageva, MD, Meletios Athanasios Dimopoulos, MD, Ofer Shpilberg, MD, MPH, Martin Kropff, MD, Ivan Spicka, MD, PhD, Maria T Petrucci, Antonio Palumbo, MD, Olga S Samoilova, MD, Anna Dmoszynska, Kudrat M Abdulkadyrov, Prof, Michel Delforge, MD, PhF, Bin Jiang, María-Victoria Mateos, MD, PhD, Kenneth C. Anderson, MD, Dixie-Lee Esseltine, MD, FRCPC, Kevin Liu, PhD, William M Deraedt, PhD, Andrew Z Cakana, MD, FRCPath, Helgi van de Velde, MD, PhD, Paul G. Richardson, MD
Journal: Blood
Blood (2011) 118 (21): 476.
https://doi.org/10.1182/blood.V118.21.476.476
Published: 2011
Journal Articles

Phase II Trial of Lenalidomide, Bortezomib, and Dexamethasone In Patients (pts) with Relapsed and Relapsed/Refractory Multiple Myeloma (MM): Updated Efficacy and Safety Data After >2 Years of Follow-up

Paul G Richardson, MD, Sundar Jagannath, MD, Andrzej J Jakubowiak, MD, PhD, Sagar Lonial, MD, Noopur Raje, MD, Melissa Alsina, MD, Irene Ghobrial, MD, Robert L. Schlossman, MD, Amitabha Mazumder, MD, Nikhil C. Munshi, MD, David H. Vesole, MD, PhD, Kathleen Colson, RN, BSN, BS, Mary L McKenney, MSN, Laura E Lunde, BA, John Feather, Teru Hideshima, MD, PhD, Robert D Knight, MD, Dixie-Lee Esseltine, MD, FRCPC, Constantine S. Mitsiades, MD, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2010) 116 (21): 3049.
https://doi.org/10.1182/blood.V116.21.3049.3049
Published: 2010
Journal Articles

Hematological Testing Is Not Required with Every Dose of Bortezomib In Patients with Adequate Blood Counts at the Start of Each Cycle

Pooja S. Raibagkar, MD, Paul G Richardson, Pieter Sonneveld, Michael W. Schuster, MD, David Irwin, MD, Edward A. Stadtmauer, MD, Thierry Facon, MD, Jean-Luc Harousseau, MD, Dina Ben-Yehuda, Sagar Lonial, MD, Hartmut Goldschmidt, Donna E. Reece, MD, Jesus F San Miguel, Joan Blade, Mario Boccadoro, Rachel Neuwirth, MS, Dixie-Lee Esseltine, MD, FRCPC, Kenneth C. Anderson, Nikhil C. Munshi, MD
Journal: Blood
Blood (2010) 116 (21): 1963.
https://doi.org/10.1182/blood.V116.21.1963.1963
Published: 2010
Journal Articles

Proteasome Inhibitor Bortezomib Has Antitumour Activity Against Both CD34 Negative and CD34 Positive Acute Myeloid Leukemia Cells.

Enrique Colado, MD, Jesus Martin, MD, Maria-Belen Vidriales, MD,PhD, Atanasio Pandiella, MD,PhD, Dixie-Lee Esseltine, MD,FRCPC, Jose J. Perez, Enrique M. Ocio, MD,PhD, J.F. San Miguel, MD,PhD
Journal: Blood
Blood (2006) 108 (11): 1989.
https://doi.org/10.1182/blood.V108.11.1989.1989
Published: 2006