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David A. Wilcox, PhD
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Journal Articles

Tissue-Specific Transgene Expression in Induced Pluripotent Stem (iPS) Cell-Derived Megakaryocytes: Correction of Glanzmann Thrombasthenia (GT)

Spencer K. Sullivan, MD, Jason A. Mills, PhD, Li Zhai, MD, Prasuna Paluru, MS, Karen Vo, Michele Lambert, MD, Sevasti B. Koukouritaki, PhD, Juan Fang, MD, David A. Wilcox, PhD, Deborah L. French, PhD, Mortimer Poncz, MD, Paul Gadue, PhD
Journal: Blood
Blood (2012) 120 (21): 387.
https://doi.org/10.1182/blood.V120.21.387.387
Published: 2012
Journal Articles

Disaggregation Signals Initiated by Ligand Binding and Platelet Aggregation

Cunji Gao, MD, PhD, Juan Fang, MD, Huiying Zhi, PhD, David A. Wilcox, PhD, Peter J. Newman, PhD
Journal: Blood
Blood (2011) 118 (21): 2196.
https://doi.org/10.1182/blood.V118.21.2196.2196
Published: 2011
Journal Articles

De Novo Synthesis & Storage of Human Factor VIII In Platelets Reduces Bleeding In Canine Hemophilia A

Lily M. Du, MD, Helen W.G. Franck, BS, Elizabeth P. Merricks, PhD, Paquita Nurden, MD, Eric S. Jensen, DVM, Sandra L. Haberichter, PhD, Troy B. Hawkins, PhD, Paula M. Jacobi, BS, Juan Fang, MD, Timothy C. Nichols, MD, Sevasti B. Koukouritaki, PhD, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD, Kenneth Cornetta, MD, Alan T. Nurden, PhD, David A. Wilcox, PhD
Journal: Blood
Blood (2010) 116 (21): 2198.
https://doi.org/10.1182/blood.V116.21.2198.2198
Published: 2010
Journal Articles

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Scot A. Fahs, David A. Wilcox, PhD, Robert R. Montgomery, MD
Journal: Blood
Blood (2010) 116 (21): 2201.
https://doi.org/10.1182/blood.V116.21.2201.2201
Published: 2010
Journal Articles

Platelet-Targeted Expression of Human BDD-FVIII Reduces Bleeding in Canine Hemophilia A.

Lily M. Du, MS, MD, Timothy C. Nichols, MD, Sandra L. Haberichter, PhD, Paula M. Jacobi, Eric S. Jensen, DVM, Juan Fang, MD, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD, David A. Wilcox, PhD
Journal: Blood
Blood (2009) 114 (22): 691.
https://doi.org/10.1182/blood.V114.22.691.691
Published: 2009
Journal Articles

Sustained Phenotypic Correction of Murine Hemophilia A with Pre-Existing Anti-FVIII Immunity Using Lentivirus-Mediated Platelet-Specific FVIII Gene Transfer.

Qizhen Shi, MD, PhD, Erin L. Kuether, Brian C. Cooley, Ph.D., Scot A. Fahs, Jocelyn A. Schroeder, David A. Wilcox, PhD, Robert R. Montgomery, MD
Journal: Blood
Blood (2009) 114 (22): 29.
https://doi.org/10.1182/blood.V114.22.29.29
Published: 2009
Journal Articles

High Mortality in Mice with Platelets Expressing Integrin αIIbβ3 Lockedin Its High Affinity State.

David A. Wilcox, PhD, Juan Fang, MD, Paula North, MD, PhD, Paquita Nurden, MD, Alan T. Nurden, PhD, Nathalie Valentin, PhD
Journal: Blood
Blood (2008) 112 (11): 1832.
https://doi.org/10.1182/blood.V112.11.1832.1832
Published: 2008
Journal Articles

Recombinant Human HPA-1A Antibodies for Treatment of Fetomaternal Alloimmune Thrombocytopenia (FMAIT): Proof of Principle in An in Vivo Murine Model and Human Volunteer Studies

Cedric Ghevaert, David A. Wilcox, PhD, Juan Fang, Kathryn Armour, Mike R Clark, Willem H. Ouwehand, Lorna M Williamson
Journal: Blood
Blood (2008) 112 (11): 85.
https://doi.org/10.1182/blood.V112.11.85.85
Published: 2008
Journal Articles

Platelet-Targeted Expression of Coagulation Factor VIII (FVIII) Shows Efficacy for Using the Dog as a Large Animal Model for Gene Therapy of Hemophilia a

David A. Wilcox, PhD, Lily M. Du, MS, MD, Sandra L. Haberichter, PhD, Paula M. Jacobi, Juan Fang, MD, Eric S. Jensen, DVM, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD
Journal: Blood
Blood (2008) 112 (11): 3525.
https://doi.org/10.1182/blood.V112.11.3525.3525
Published: 2008
Journal Articles

Blockade of Chemotherapy-Induced Thrombocytopenia by Bax Inhibiting Peptides (BIPs) in Mouse Model.

Jose A. Gomez, MSc, Vivian Gama, MSc, Tomoyuki Yoshida, PhD, Michelle Stapleton, PhD, Cathy Paddock, MSc, David A. Wilcox, PhD, Peter J. Newman, PhD, Eimei Sato, PhD, Shigemi Matsuyama, PhD
Journal: Blood
Blood (2007) 110 (11): 281.
https://doi.org/10.1182/blood.V110.11.281.281
Published: 2007
Journal Articles

Intravenous Immunoglobulin (IVIG) Diminishes Immune-Mediated Clearance of Platelets Expressing an Integrin αIIbβ3 Transgene Product That Restores Hemostasis in a Canine Model for Glanzmann Thrombasthenia.

Juan Fang, MD, Eric S. Jensen, DVM, Lily M. Du, MD,Ms, Mary K. Boudreaux, DVM,PhD, David A. Wilcox, PhD
Journal: Blood
Blood (2006) 108 (11): 3263.
https://doi.org/10.1182/blood.V108.11.3263.3263
Published: 2006
Journal Articles

Phenotypic Correction of a Canine Model for Glanzmann Thrombasthenia Demonstrates Efficacy for Using Platelets To Deliver Therapeutics at the Site of Vascular Injury.

David A. Wilcox, PhD, Juan Fang, Lily M. Du, Mary K. Boudreaux, PhD, DVM
Journal: Blood
Blood (2005) 106 (11): 3045.
https://doi.org/10.1182/blood.V106.11.3045.3045
Published: 2005
Journal Articles

Murine Platelets Expressing a Polymorphism of Integrin β3 Associated with Acute Coronary Thrombosis in Humans.

David A. Wilcox, PhD, Juan Fang, MD, Bryon D. Johnson, PhD
Journal: Blood
Blood (2004) 104 (11): 3896.
https://doi.org/10.1182/blood.V104.11.3896.3896
Published: 2004