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Damian R. Handisides
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Journal Articles

A Phase 1 Study Of TH-302, An Investigational Hypoxia-Targeted Drug, In Patients With Advanced Leukemias

Marina Konopleva, MD, PhD, Damian R Handisides, Mary Ann Richie, RN, Juliana M Benito, PhD, Gautam Borthakur, MD, Elias J. Jabbour, MD, Stefan H. Faderl, MD, Jorge E. Cortes, MD, Stewart Kroll, Michael Andreeff, MD, PhD, Hagop M Kantarjian, MD, Deborah A. Thomas, MD
Journal: Blood
Blood (2013) 122 (21): 3920.
https://doi.org/10.1182/blood.V122.21.3920.3920
Published: 2013
Journal Articles

Phase 1 Study Of TH-302, An Investigational Hypoxia-Targeted Drug, and Dexamethasone In Patients With Relapsed/Refractory Multiple Myeloma

Irene M. Ghobrial, MD, Jacob P. Laubach, MD, Noopur Raje, MD, Philippe Armand, MD, PhD, Robert L. Schlossman, MD, Erica N Boswell, BS, Courtney Hanlon, Stacey Chuma, BSN, Damian R Handisides, Stewart Kroll, Kenneth C. Anderson, MD, Paul G. Richardson, MD
Journal: Blood
Blood (2013) 122 (21): 1948.
https://doi.org/10.1182/blood.V122.21.1948.1948
Published: 2013
Journal Articles

Leukemia Microenvironment and Pathologic Hypoxia: Sensitivity to Hypoxia-Activated Cytotoxin TH-302

Juliana M Benito, PhD, Volgin Y Andrei, Ye Chen, PhD, Lu Hongbo, Yuexi Shi, Teresa McQueen, Patrick A Zweidler-McKay, MD, PhD, Damian R Handisides, Charles Hart, Michael Andreeff, MD, PhD, Marina Konopleva, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 1523.
https://doi.org/10.1182/blood.V120.21.1523.1523
Published: 2012
Journal Articles

Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug

Brief Report
Jinsong Hu, Damian R. Handisides, Els Van Valckenborgh, Hendrik De Raeve, Eline Menu, Isabelle Vande Broek, Qian Liu, Jessica D. Sun, Ben Van Camp, Charles P. Hart, Karin Vanderkerken
Journal: Blood
Blood (2010) 116 (9): 1524–1527.
https://doi.org/10.1182/blood-2010-02-269126
Published: 2010
Includes: Supplemental data
Journal Articles

Hypoxia Activated Prodrug TH-302 for the Treatment of Multiple Myeloma.

Jinsong Hu, Damian R Handisides, Els Van Valckenborgh, Hendrik De Raeve, Eline Menu, Isabelle Vande Broek, Qian Liu, Jessica D Sun, Ben Van Camp, Charles Hart, Karin Vanderkerken
Journal: Blood
Blood (2009) 114 (22): 3838.
https://doi.org/10.1182/blood.V114.22.3838.3838
Published: 2009