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Constantine S. Mitsiades, M.D.
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Journal Articles

The Interaction of Bortezomib with P-Gp, MRP-1 and BCRP Drug Transporters: Implications for Therapeutic Applications of Bortezomib in Advanced Multiple Myeloma and Other Neoplasias.

Melissa G Ooi, M.D., Robert O'Connor, Ph.D, Jana Jakubikova, Ph.D, Justine Meiller, Diploma, in, Biochemistry, Degre, Steffen Klippel, Ph.D, Jake Delmore, Efstathios Kastritis, M.D, Douglas McMillin, Ph.D, Martin Clynes, Ph.D, Paul Richardson, M.D., Constantine S. Mitsiades, M.D., Ph.D, Peter O'Gorman, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2009) 114 (22): 1729.
https://doi.org/10.1182/blood.V114.22.1729.1729
Published: 2009
Journal Articles

The Transcriptional Signature of Kinases Inhibited by the Multi-Targeted Kinase Inhibitor AS703569 Is Associated with Clinical Outcome in Multiple Myeloma (MM): Anti-MM Activity of AS703569 in Preclinical Studies.

Jake Delmore, David N. Cervi, Douglas McMillin, Efstathios Kastritis, Jana Jakubikova, Melissa G. Ooi, Steffen Klippel, Joseph M. Negri, Leutz Buon, Jacob Laubach, Luca Rastelli, Ann Clark, Samantha M. Sarno, Paul G. Richardson, Kenneth C. Anderson, Constantine S. Mitsiades, M.D., Ph.D
Journal: Blood
Blood (2009) 114 (22): 730.
https://doi.org/10.1182/blood.V114.22.730.730
Published: 2009
Journal Articles

Targeting the Clonogenic Side Population of Multiple Myeloma by Immunomodulatory Drugs (IMiDs) in the Context of Stromal Cell Microenvironment: Pathophysiologic and Clinical Implications.

Jana Jakubikova, David N. Cervi, John F. Daley, Danka Cholujova, Melissa G. Ooi, Steffen Klippel, Simona Blotta, Merav Leiba, Jake Delmore, Douglas McMillin, Efstathios Kastritis, Jacob Laubach, Paul Richardson, Jan Sedlak, Kenneth C. Anderson, Constantine S. Mitsiades, M.D., Ph.D
Journal: Blood
Blood (2009) 114 (22): 954.
https://doi.org/10.1182/blood.V114.22.954.954
Published: 2009
Journal Articles

Proteomics as a Functional Tool in Evaluating Bortezomib Treatment and Drug Resistance Mechanism.

Melissa G Ooi, M.D., Paul Dowling, Ph.D, Paul Richardson, M.D., Constantine S. Mitsiades, M.D., Ph.D, Martin Clynes, Ph.D, Kenneth C. Anderson, Peter O'Gorman, M.D.
Journal: Blood
Blood (2009) 114 (22): 1805.
https://doi.org/10.1182/blood.V114.22.1805.1805
Published: 2009
Journal Articles

Anti-Tumor Activity of IPI-504, a Novel Hsp90 Inhibitor in Multiple Myeloma.

Vito J. Palombella, Ph.D., Emmanuel Normant, Ph.D., Janid Ali, Ph.D., John Barrett, Ph.D., Michael Foley, Ph.D., Yun Gao, Ph.D., Jennie Ge, Ph.D., Asimina T. Georges, Ph.D., David Grayzel, M.D., Louis Grenier, Jebecka Hudak, Roger Pak, Ph.D., Jon Patterson, Christine Pien, Melissa Pink, James Porter, Ph.D., Junbiao Sang, Kerry Spear, Ph.D., Jens Sydor, Ph.D., Jim Wright, Ph.D., Constantine S. Mitsiades, M.D., Kenneth C. Anderson, M.D., Julian Adams, Ph.D., Jeffrey Tong, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 4922.
https://doi.org/10.1182/blood.V104.11.4922.4922
Published: 2004
Journal Articles

PKC412 Effectively Inhibits Constitutively Activated FGFR3 Mutants in Murine Leukemia Models and t(4;14) Myeloma Cell Lines.

Jing Chen, Ph.D., Benjamin H. Lee, M.D., Ph.D., Ifor R. Williams, M.D., Ph.D., Jeffery L. Kutok, M.D., Ph.D., Nicole Duclos, Sarah Cohen, Jennifer Adelsperger, Rachel Okabe, Allison Coburn, Sandra Moore, Brian J.P. Huntly, M.D., Ph.D., Constantine S. Mitsiades, M.D., Kenneth C. Anderson, M.D., James D. Griffin, M.D., Doriano Fabbro, Ph.D., D. Gary Gilliland, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2448.
https://doi.org/10.1182/blood.V104.11.2448.2448
Published: 2004