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Journal Articles

The GSK3β-Phosphorylation Sites in the DEK-Portion Are Indispensable for the Leukemogenic Potential of the DEK/CAN Fusion Protein in t(6;9)-Positive Acute Myeloid Leukemia

Claudia Oancea, PhD, Maria Heinßmann, Nathalie Guillen, Oliver G. Ottmann, MD, Martin Ruthardt, MD

Blood (2014) 124 (21): 3574.

https://doi.org/10.1182/blood.V124.21.3574.3574

Published: 2014

Journal Articles

The Functional Interplay Between the t(9;22)-Associated Fusion Proteins BCR/ABL and ABL/BCR in Philadelphia Chromosome Positive Acute Lymphatic Leukemia

Afsar Mian, PhD, Anahita Rafiei, Claudia Oancea, PhD, Oliver G. Ottmann, MD, Martin Ruthardt, MD

Blood (2014) 124 (21): 2402.

https://doi.org/10.1182/blood.V124.21.2402.2402

Published: 2014

Journal Articles

The Reciprocal t(9;22) p96 ABL/BCR fusion Protein Eenhances the Transformation Potential of BCR/ABL and Increases Therapy Resistance in Models of Ph+ Acute Lymphatic Leukemia

Anahita Rafiei, Afsar Mian, PhD, Anna Metodieva, Claudia Oancea, Hubert Serve, MD, Heike Pfeifer, MD, Oliver G. Ottmann, MD, Martin Ruthardt, MD

Blood (2012) 120 (21): 3539.

https://doi.org/10.1182/blood.V120.21.3539.3539

Published: 2012

Journal Articles

T(6;9)-DEK/CAN-Positive Leukemia: Role of FLT3-ITD for the Determination of the Leukemic Phenotype

Maria Heinssmann, Lena Drangmeister, Katharina Schmid, Maren Keller, Hubert Serve, Prof. Dr. med., Claudia Oancea, Martin Ruthardt, MD, Gesine Bug

Blood (2012) 120 (21): 1316.

https://doi.org/10.1182/blood.V120.21.1316.1316

Published: 2012

Journal Articles

Enzymatically Inactive 5-Lipoxygenase Inhibits Wnt-Signaling Activation Induced by Leukemia Inducing Oncogenes.

Jessica Roos, Maria Heinßmann, Claudia Oancea, Thorsten Maier, Dieter Steinhilber, Hubert Serve, MD, Martin Ruthardt, MD

Blood (2012) 120 (21): 2424.

https://doi.org/10.1182/blood.V120.21.2424.2424

Published: 2012

Journal Articles

The Activation of STAT3 and 5 in t(6;9)(DEK/CAN)-Positive Acute Myeloid Leukemia Models Is Inhibited by Exposure to Arsenic Trioxide

Claudia Oancea, Hannelore Held, Maria Heinssmann, Boris Brill, Hubert Serve, Prof. Dr. med., Martin Ruthardt, MD

Blood (2012) 120 (21): 1384.

https://doi.org/10.1182/blood.V120.21.1384.1384

Published: 2012

Journal Articles

“Hierarchical” Induction and “Stochastic” Maintenance of Leukemia in An In Vivo Model of t(6;9) Positive Acute Myeloid Leukemia.

Claudia Oancea, Brigitte Rüster, Jessica Roos, Anjali Dubey, Hannelore Held, Tatjana Micheilis, Hubert Serve, Reinhard Henschler, Martin Ruthardt

Blood (2009) 114 (22): 2953.

https://doi.org/10.1182/blood.V114.22.2953.2953

Published: 2009

Journal Articles

T(15;17)-PML/RAR-Induced Leukemogenesis: Long-Term Repopulating Hematopoietic Stem Cells as the Initial Target and More Mature Progenitors as the Potential Targets for Final Leukemic Transformation.

Claudia Oancea, Brigitte Rüster, PhD, Jessica Roos, Afsar Ali Mian, Tatjana Micheilis, Hannelore Held, Anjali Dubey, Hubert Serve, Reinhard Henschler, Martin Ruthardt

Blood (2009) 114 (22): 3980.

https://doi.org/10.1182/blood.V114.22.3980.3980

Published: 2009

Journal Articles

Oligomerization Inhibition Combined with Allosteric Inhibition Abrogates the Transformation Potential of T315I-Positive BCR/ABL.

Afsar Ali Mian, Claudia Oancea, Zihan Zhao, Hubert Serve, MD, PhD, Ottmann Oliver, Martin Ruthardt, MD

Blood (2009) 114 (22): 2964.

https://doi.org/10.1182/blood.V114.22.2964.2964

Published: 2009

Journal Articles

Overexpression of APC Reduces Stem Cell Capacity and Leukemogenic Potential of PLZF/RAR-Positive Leukemic Stem Cells.

Anita Seshire, PhD, Tim Beissert, PhD, Claudia Oancea, PhD, Dieter Hoelzer, PhD, MD, Martin Ruthardt, MD, Elena Puccetti, PhD

Blood (2007) 110 (11): 874.

https://doi.org/10.1182/blood.V110.11.874.874

Published: 2007

Journal Articles

The t(6;9) Associated DEK/CAN Fusion Protein Does Not Block Differentiation of Early Hematopoietic Stem Cells but Increases Their Stem Cell Capacity.

Claudia Oancea, PhD, Elena Puccetti, PhD, Reinhard Henschler, PhD, Martin Ruthardt, MD, Gesine Bug, MD

Blood (2007) 110 (11): 882.

https://doi.org/10.1182/blood.V110.11.882.882

Published: 2007

Journal Articles

The Acute Promyelocytic Leukemia (APL)-Associated Fusion Proteins PML/RAR and PLZF/RAR Directly Bind to and Inhibit GATA-1.

Anita Seshire, MSc, Claudia Oancea, PhD, Dieter Hoelzer, MD, Martin Ruthardt, MD, Elena Puccetti, PhD

Blood (2006) 108 (11): 1929.

https://doi.org/10.1182/blood.V108.11.1929.1929

Published: 2006

NARROW

The GSK3β-Phosphorylation Sites in the DEK-Portion Are Indispensable for the Leukemogenic Potential of the DEK/CAN Fusion Protein in t(6;9)-Positive Acute Myeloid Leukemia

The Functional Interplay Between the t(9;22)-Associated Fusion Proteins BCR/ABL and ABL/BCR in Philadelphia Chromosome Positive Acute Lymphatic Leukemia

The Reciprocal t(9;22) p96 ABL/BCR fusion Protein Eenhances the Transformation Potential of BCR/ABL and Increases Therapy Resistance in Models of Ph+ Acute Lymphatic Leukemia

T(6;9)-DEK/CAN-Positive Leukemia: Role of FLT3-ITD for the Determination of the Leukemic Phenotype

Enzymatically Inactive 5-Lipoxygenase Inhibits Wnt-Signaling Activation Induced by Leukemia Inducing Oncogenes.

The Activation of STAT3 and 5 in t(6;9)(DEK/CAN)-Positive Acute Myeloid Leukemia Models Is Inhibited by Exposure to Arsenic Trioxide

“Hierarchical” Induction and “Stochastic” Maintenance of Leukemia in An In Vivo Model of t(6;9) Positive Acute Myeloid Leukemia.

T(15;17)-PML/RAR-Induced Leukemogenesis: Long-Term Repopulating Hematopoietic Stem Cells as the Initial Target and More Mature Progenitors as the Potential Targets for Final Leukemic Transformation.

Oligomerization Inhibition Combined with Allosteric Inhibition Abrogates the Transformation Potential of T315I-Positive BCR/ABL.

Overexpression of APC Reduces Stem Cell Capacity and Leukemogenic Potential of PLZF/RAR-Positive Leukemic Stem Cells.

The t(6;9) Associated DEK/CAN Fusion Protein Does Not Block Differentiation of Early Hematopoietic Stem Cells but Increases Their Stem Cell Capacity.

The Acute Promyelocytic Leukemia (APL)-Associated Fusion Proteins PML/RAR and PLZF/RAR Directly Bind to and Inhibit GATA-1.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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