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Afsar Ali Mian
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Journal Articles

Arsenic Trioxide Suppresses Growth of BCR-ABL1 Positive Cells with "Gatekeeper" or Compound Mutation

Free
Afsar Ali Mian, Hadiqa Raees, Sujjawal Ahmad, Oliver Ottmann, El-Nasir M A Lalani
Journal: Blood
Blood (2021) 138 (Supplement 1): 4346.
https://doi.org/10.1182/blood-2021-154511
Published: 2021
Journal Articles

Activation of AKT/mTOR Pathway in Ph+ Acute Lymphoblastic Leukemia (ALL) Leads to Non-Mutational Resistance

Free
Afsar Ali Mian, BSc, MPhil, PhD, Usva Zafar, BSc, Oliver Ottmann, Prof, MD, Martin Ruthardt, MD, El-Nasir M A Lalani, BSc MBChB FRCPath PhDFHEA
Journal: Blood
Blood (2019) 134 (Supplement_1): 2570.
https://doi.org/10.1182/blood-2019-130898
Published: 2019
Journal Articles

The ''Gatekeeper'' Mutation T315I in BCR/ABL Confers Additional Oncogenic Activities to Philadelphia Chromosome Positive Leukemia

Free
Usva Zafar, BSc, Mohammed Yusuf, PhD, Rikhia Chakraborty, PhD, El-Nasir M A Lalani, BSc MBChB FRCPath PhDFHEA, Afsar Ali Mian, BSc, MPhil, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5196.
https://doi.org/10.1182/blood-2019-131694
Published: 2019
Journal Articles

CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells

Free
Mateusz Legut, Garry Dolton, Afsar Ali Mian, Oliver G. Ottmann, Andrew K. Sewell
Journal: Blood
Blood (2018) 131 (3): 311–322.
https://doi.org/10.1182/blood-2017-05-787598
Published: 2018
Includes: Supplemental data
Journal Articles

T(15;17)-PML/RAR-Induced Leukemogenesis: Long-Term Repopulating Hematopoietic Stem Cells as the Initial Target and More Mature Progenitors as the Potential Targets for Final Leukemic Transformation.

Free
Claudia Oancea, Brigitte Rüster, PhD, Jessica Roos, Afsar Ali Mian, Tatjana Micheilis, Hannelore Held, Anjali Dubey, Hubert Serve, Reinhard Henschler, Martin Ruthardt
Journal: Blood
Blood (2009) 114 (22): 3980.
https://doi.org/10.1182/blood.V114.22.3980.3980
Published: 2009
Journal Articles

Oligomerization Inhibition Combined with Allosteric Inhibition Abrogates the Transformation Potential of T315I-Positive BCR/ABL.

Free
Afsar Ali Mian, Claudia Oancea, Zihan Zhao, Hubert Serve, MD, PhD, Ottmann Oliver, Martin Ruthardt, MD
Journal: Blood
Blood (2009) 114 (22): 2964.
https://doi.org/10.1182/blood.V114.22.2964.2964
Published: 2009