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Journal Articles

Hydroxyurea Decreases Transfusion Utilization in Ugandan Children with Sickle Cell Anemia: Main Results from the Alternative Dosing and Prevention of Transfusions (ADAPT) Trial

Alexandra Power-Hays, Ruth Namazzi, Charles Kato, Andrea Conroy, Heather Ann Hume, Chandy C. John, Robert Opoka, Susan E. Stuber, Adam C. Lane, Teresa S. Latham, Russell E. Ware
Journal: Blood
Blood (2024) 144 (Supplement 1): 546.
https://doi.org/10.1182/blood-2024-211666
Published: 2024
Journal Articles

Hydroxyurea Pharmacokinetics in Children with Sickle Cell Anemia: Comparison of Global Cohorts

Alexandra Power-Hays, Kathryn E. McElhinney, Teresa S. Latham, Tom N. Williams, George Mochamah, Peter Olupot-Olupot, George Paasi, Marvin Ellsworth Reid, Angela Rankine-Mullings, Robert Opoka, Chandy C. John, Patrick T. McGann, Charles T. Quinn, Susan E. Stuber, Russell E. Ware
Journal: Blood
Blood (2024) 144 (Supplement 1): 542.
https://doi.org/10.1182/blood-2024-201577
Published: 2024
Journal Articles

Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

Clinical Trials & Observations
Ruth Namazzi, Caitlin Bond, Andrea L. Conroy, Dibyadyuti Datta, Abner Tagoola, Michael J. Goings, Jeong Hoon Jang, Russell E. Ware, Robert Opoka, Chandy C. John
Journal: Blood
Blood (2024) 143 (14): 1425–1428.
https://doi.org/10.1182/blood.2023021575
Published: 2024
Includes: Supplemental data
Journal Articles

Pharmacokinetic-Guided Hydroxyurea to Reduce Transfusion Requirements in Ugandan Children with Sickle Cell Anemia: Baseline Data from the Alternative Dosing and Prevention of Transfusions (ADAPT) Trial

Alexandra Power-Hays, Ruth Namazzi, Charles Kato, Andrea Conroy, Heather Ann Hume, Chandy C. John, Susan E. Stuber, Adam C. Lane, Teresa S. Latham, Robert Opoka, Russell E. Ware
Journal: Blood
Blood (2023) 142 (Supplement 1): 1156.
https://doi.org/10.1182/blood-2023-181058
Published: 2023
Journal Articles

Malaria in Children with Sickle Cell Anaemia in Areas with Low, Moderate and High Transmission in Uganda

Ruth Namazzi, Richard Idro, Dennis Kalibala, John Ssenkusu, Pamela Akun, Vincent Mboizi, Thandile Nkosi Gondwe, Deogratias Munube, Philip Kasirye, Catherine Nabaggala, Chandy C. John, Nancy S. Green, Bjarne Robberstat, Boele van Hensbroek, Feiko ter Kuile, Kamija S. Phiri, Robert Opoka
Journal: Blood
Blood (2023) 142 (Supplement 1): 5327.
https://doi.org/10.1182/blood-2023-189066
Published: 2023
Journal Articles

Effect of Hydroxyurea Therapy on the Incidence of Infections in Ugandan Children with Sickle Cell Anaemia

Ruth Namazzi, Andrea L. Conroy, Caitlin Bond, Micheal J. Goings, Dibyadyuti Datta, Russell E. Ware, Jeong Hoon Jang, Chandy C. John, Robert O. Opoka
Journal: Blood
Blood (2021) 138 (Supplement 1): 765.
https://doi.org/10.1182/blood-2021-153559
Published: 2021
Journal Articles

Novel Genetic Loci That Influence Fetal Hemoglobin Expression in Children with Sickle Cell Anemia

Anu Marahatta, PhD, Thad A. Howard, MS, Susan E. Stuber, MA, Kathryn L McElhinney, BS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Chandy C. John, MD MS, Robert Opoka, MMED, Rosa M. Nieves, MD, Rafael Mena, MD, Jasmine Baker, PhD, Teresa Latham, MA, Jonathan M. Flanagan, PhD, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-143025
Published: 2020
Journal Articles

Genetic Variants That Influence Fetal Hemoglobin Expression from Hydroxyurea Treatment

Anu Marahatta, PhD, Jonathan M. Flanagan, PhD, Thad A. Howard, MS, Nicole Mortier, MHS, PA-C, William Schultz, MHS, PA, Kathryn L McElhinney, BS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Chandy C. John, MD MS, Robert Opoka, MMED, Rosa M. Nieves, MD, Rafael Mena, MD, Marvin E Reid, MB, BS, PhD, Angela Rankine-Mullings, MBBS, Jasmine Baker, PhD, Patrick T. McGann, MD MS, Banu Aygun, MD, Adam Lane, PhD, George A. Tomlinson, PhD BSc, MSc, Teresa Latham, MA, Susan E. Stuber, MA, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-143139
Published: 2020
Journal Articles

Impact of a National Lockdown for COVID-19 on Morbidity and Mortality Among Children with Sickle Cell Anaemia at a Tertiary Care Hospital in Uganda

Ruth Namazzi, MD, Robert Opoka, MMED, Andrea L Conroy, PhD, Dibyadyuti Datta, PhD, Micheal Goings, MPH, Chandy C. John, MD MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-142417
Published: 2020
Journal Articles

Optimizing Hydroxyurea Dosing in Sickle Cell Anemia: The Uganda MTD Study

Chandy C. John, MDMS, Robert Opoka, MMED, Teresa Latham, MA, Heather Hume, MDFRCPC, Maria Nakafeero, Phillip Kasirye, Christopher Ndugwa, Adam Lane, PhD, Russell E. Ware, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 520.
https://doi.org/10.1182/blood-2019-125128
Published: 2019
Journal Articles

Profound Alteration of Host Response in Severe Malarial Anemia By Sickle Cell Disease: Reduction of Parasite Sequestration and Inflammation, Upregulation of Angiopoietin-2

Ryan C Henrici, PhD BS, Casey Sautter, MDMS, Robert Opoka, MMED, Ruth Namazzi, MD, Gregory S Park, Dibyadyuti John, PhD, Andrea L Conroy, PhD, Russell E. Ware, MD PhD, Chandy C. John, MDMS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2283.
https://doi.org/10.1182/blood-2019-129566
Published: 2019
Journal Articles

Long Term Haematological Recovery of Children with Severe Malaria Anaemia in Uganda

Ruth Namazzi, MD, Andrea L Conroy, PhD, Dibyadyuti Datta, PhD, Chandy C. John, MDMS, Robert Opoka, MMED
Journal: Blood
Blood (2019) 134 (Supplement_1): 4698.
https://doi.org/10.1182/blood-2019-132170
Published: 2019
Journal Articles

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia

Clinical Trials & Observations
Robert O. Opoka, Christopher M. Ndugwa, Teresa S. Latham, Adam Lane, Heather A. Hume, Phillip Kasirye, James S. Hodges, Russell E. Ware, Chandy C. John
Journal: Blood
Blood (2017) 130 (24): 2585–2593.
https://doi.org/10.1182/blood-2017-06-788935
Published: 2017
Journal Articles

Novel Use of Hydroxyurea in an African Region with Malaria (NOHARM): A Randomized Controlled Trial

Robert Opoka, Christopher Ndugwa, MMED, Teresa S. Latham, Adam Lane, Heather Ann Hume, MDFRCPC, Philip Kasirye, MD, James L Hodges, PhD, Russell E. Ware, MD PhD, Chandy C John, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 759.
https://doi.org/10.1182/blood.V130.Suppl_1.759.759
Published: 2017
Journal Articles

Pharmacokinetics of Hydroxyurea Therapy in African Children with Sickle Cell Anemia:Â Noharm Ancillary PK Study

Anu Marahatta, PhD, Min Dong, PhD, Robert Opoka, Kathryn E. McElhinney, Teresa S. Latham, Chandy C. John, MDMS, Alexander A. Vinks, Russell E. Ware, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2252.
https://doi.org/10.1182/blood.V130.Suppl_1.2252.2252
Published: 2017