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Journal Articles

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Swapna Thota, MD, Srinivasa Reddy Sanikommu, MD, Bhumika Patel, MD, Meena Sadaps, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Serena Marotta, MD, Antonio M Risitano, MD PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1505.

https://doi.org/10.1182/blood.V128.22.1505.1505

Published: 2016

Journal Articles

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1506.

https://doi.org/10.1182/blood.V128.22.1506.1506

Published: 2016

Journal Articles

Molecular and Immunophenotypic Characteristics of Adult Acute Leukemias of Ambiguous Lineage

Bhumika Patel, MD, Caner Saygin, MD, Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Betty K. Hamilton, MD, Anjali S. Advani, MD, Aziz Nazha, MD, Sarah Lynn Ondrejka, DO, Matt Kalaycio, MD, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1659.

https://doi.org/10.1182/blood.V128.22.1659.1659

Published: 2016

Journal Articles

UTX mutations in Myeloid Neoplasms

Yasunobu Nagata, MD,PhD, Tomas Radivoyevitch, PhD, Hideki Makishima, MD PhD FACP., Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Teodora Kuzmanovic, BSc, Eiju Negoro, MD, PhD, Michael J. Clemente, M.S., Sudipto Mukherjee, MD, PhD, M.P.H., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3148.

https://doi.org/10.1182/blood.V128.22.3148.3148

Published: 2016

Journal Articles

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

Bhumika Patel, MD, Bartlomiej P Przychodzen, MSc, Michael J. Clemente, M.S., Cassandra M. Hirsch, BSc, Caner Saygin, MD, Marissa Versalle, MD, Swapna Thota, MD, Aziz Nazha, MD, Roy Souaid, MD, Valeria Visconte, PhD, Taha Bat, MD, Suresh Kumar Balasubramanian, MD, Tomas Radivoyevitch, PhD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3892.

https://doi.org/10.1182/blood.V128.22.3892.3892

Published: 2016

Journal Articles

U2AF1 Mutations in S34 and Q157 Create Distinct Molecular and Clinical Contexts

Vera Adema, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Aziz Nazha, MD, Teodora Kuzmanovic, Eiju Negoro, MD, PhD, Dewen You, PhD, Hideki Makishima, MD PhD FACP., Michael J. Clemente, M.S., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 3155.

https://doi.org/10.1182/blood.V128.22.3155.3155

Published: 2016

Journal Articles

Clinical and Biological Implications of CUX1 Mutations in Myeloid Neoplasms

Mai Aly, Naoko Hosono, MD,PhD, Przychodzen Bartlomiej, Hideki Makishima, MD PhD FACP., Nagata Yasunobu, MDPhD, Cassandra M. Hirsch, BSc, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD

Blood (2016) 128 (22): 3156.

https://doi.org/10.1182/blood.V128.22.3156.3156

Published: 2016

Journal Articles

Using Machine Intelligence Algorithms to Develop a Geno-Clinical Model to Predict Responses to Hypomethylating Agents in Myelodysplastic Syndromes

Aziz Nazha, MD, Mikkael A. Sekeres, MD MS, Rafael Bejar, MD PhD, John Barnard, PhD, Karam Al-Issa, MD, Bartlomiej P Przychodzen, MSc, Matt Kalaycio, MD, Michael J. Clemente, M.S., Cassandra M. Hirsch, BSc, Benjamin L Ebert, MD PhD, Jaroslaw P. Maciejewski

Blood (2016) 128 (22): 3193.

https://doi.org/10.1182/blood.V128.22.3193.3193

Published: 2016

Journal Articles

Pathogenic Relevance of Germ Line TET2 Alterations

Cassandra M. Hirsch, BSc, Aziz Nazha, MD, Kassy E Kneen, Manja Meggendorfer, PhD, Bartlomiej P Przychodzen, MSc, Niroshan Nadarajah, M.Sc., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Torsten Haferlach, MD, Thomas LaFramboise, PhD, Tomas Radivoyevitch, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 3160.

https://doi.org/10.1182/blood.V128.22.3160.3160

Published: 2016

Journal Articles

Quantification of Erythroblast- and Myelocyte-Derived mRNAs in Plasma Exosomes As an Indicator of Bone Marrow Status in Patients with Various Types of Anemias and Myeloproliferative Disorders

Masato Mitsuhashi, MD PhD, Taku Murakami, PhD, Teodora Kuzmanovic, Cassandra M. Hirsch, BSc, Hideki Makishima, MD, PhD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 5070.

https://doi.org/10.1182/blood.V128.22.5070.5070

Published: 2016

Journal Articles

Incorporation of Molecular Data into the Current Prognostic Models in Treated Patients with Myelodysplastic Syndromes: Which Model Is the Best

Karam Al-Issa, MD, Ahmad Zarzour, MD, Tomas Radivoyevitch, PhD, Matt Kalaycio, MD, Betty K. Hamilton, MD, Aaron T. Gerds, MD MS, Sudipto Mukherjee, MD, PhD, M.P.H., Vera Adema, PhD, Michael J. Clemente, M.S., Bhumika Patel, MD, Cassandra M. Hirsch, BSc, Anjali S. Advani, MD, Bartlomiej P Przychodzen, MSc, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP, Mikkael A. Sekeres, MD MS, Aziz Nazha, MD

Blood (2016) 128 (22): 50.

https://doi.org/10.1182/blood.V128.22.50.50

Published: 2016

Journal Articles

Germline Variants of RUNX-1 in Myeloid Malignancy

Alek d Nielsen, B.S., Sayer Alharbi, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Mikkael A. Sekeres, MD MS, Yogen Saunthararajah, MD, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3926.

https://doi.org/10.1182/blood.V128.22.3926.3926

Published: 2016

Journal Articles

A Phase 1 Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib (MLN9708) for Relapsed/ Refractory Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 4065.

https://doi.org/10.1182/blood.V128.22.4065.4065

Published: 2016

Journal Articles

Phenotype/Genotype Associations in TET2-Driven Myeloid Neoplasms

Cassandra M. Hirsch, BSc, Aziz Nazha, MD, Kassy E Kneen, Bartlomiej P Przychodzen, MSc, Niroshan Nadarajah, M.Sc., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Torsten Haferlach, MD, Tomas Radivoyevitch, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Manja Meggendorfer, PhD

Blood (2016) 128 (22): 4313.

https://doi.org/10.1182/blood.V128.22.4313.4313

Published: 2016

Journal Articles

Distinct Clinical and Biological Implications of Various DNTMT3A Mutations in Myeloid Neoplasms

Suresh Kumar Balasubramanian, MD, Mai Ali, Taha Bat, MD, Bhumika Patel, MD, Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2872.

https://doi.org/10.1182/blood.V128.22.2872.2872

Published: 2016

Journal Articles

Impact of Erythropoietic Stimulating Agents on Mutational Composition in Patients with Low-Risk Myelodysplastic Syndromes

Bhumika Patel, MD, Caner Saygin, MD, Bartlomiej P Przychodzen, MSc, Teodora Kuzmanovic, BSc, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Swapna Thota, MD, Aziz Nazha, MD, Sekeres A Mikkael, MD, Jaroslaw P Maciejewski, MD PhD FACP, Hetty E. Carraway, MD MBA

Blood (2016) 128 (22): 2002.

https://doi.org/10.1182/blood.V128.22.2002.2002

Published: 2016

Journal Articles

Molecular and Clinical Characterization of Patients with Myeloid Neoplasms Carrying the 12p Deletion

Vera Adema, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Francesc Sole, PhD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 2007.

https://doi.org/10.1182/blood.V128.22.2007.2007

Published: 2016

Journal Articles

Next-Generation Sequencing Analysis of Clonal Hierarchy and Dynamics in T-Large Granular Lymphocyte Leukemia Suggests Emergence of STAT3 Clones within Pre-Existing Dominant T-Cell Repertoire Responses Otherwise Silenced in Normal Individuals

Peter W Chomczynski, Michael J. Clemente, M.S., Srinivasa Reddy Sanikommu, MD, Alek d Nielsen, B.S., Cassandra M. Hirsch, BSc, Hanna Rajala, MD, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Satu Mustjoki, MD PhD, Alan E. Lichtin, MD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2731.

https://doi.org/10.1182/blood.V128.22.2731.2731

Published: 2016

Journal Articles

PHF6 Somatic Mutations and Their Functional Role in the Pathophysiology of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Bartlomiej P Przychodzen, MSc, Xiaorong Gu, PhD, Dewen You, PhD, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Mikkael A. Sekeres, MD MS, Aziz Nazha, MD, Hideki Makishima, MD PhD FACP., Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2736.

https://doi.org/10.1182/blood.V128.22.2736.2736

Published: 2016

Journal Articles

the Impact of Clonal Dynamics on Prognosis and Outcome in Myelodysplastic Syndromes

Hideki Makishima, MD PhD FACP., Tetsuichi Yoshizato, MD PhD, Kenichi Yoshida, MD PhD, Mikkael A. Sekeres, MD MS, Tomas Radivoyevitch, PhD, Hiromichi Suzuki, MD PhD, Bartlomiej P Przychodzen, MSc, Yasunobu Nagata, MD, PhD, Manja Meggendorfer, PhD, Masashi Sanada, MD PhD, Yusuke Okuno, MD PhD, Cassandra M. Hirsch, BSc, Teodora Kuzmanovic, Yusuke Shiozawa, MD, Yusuke Sato, MD PhD, Aiko Sato-Otsubo, Thomas LaFramboise, PhD, Naoko Hosono, MD, PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Claudia Haferlach, MD, Wolfgang Kern, MD, Hiroko Tanaka, BA, Ines Gómez-Seguí, MD PhD, Holleh Husseinzadeh, MD, Swapna Thota, MD, Kathryn M. Guinta, Brittney Dienes, Tsuyoshi Nakamaki, MD, Shuichi Miyawaki, MD PhD, Yogen Saunthararajah, MD, Shigeru Chiba, MD, PhD, Satoru Miyano, PhD, Lee-Yung Shih, MD, Torsten Haferlach, MD, Seishi Ogawa, MD PhD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 4287.

https://doi.org/10.1182/blood.V128.22.4287.4287

Published: 2016

NARROW

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

Molecular and Immunophenotypic Characteristics of Adult Acute Leukemias of Ambiguous Lineage

UTX mutations in Myeloid Neoplasms

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

U2AF1 Mutations in S34 and Q157 Create Distinct Molecular and Clinical Contexts

Clinical and Biological Implications of CUX1 Mutations in Myeloid Neoplasms

Using Machine Intelligence Algorithms to Develop a Geno-Clinical Model to Predict Responses to Hypomethylating Agents in Myelodysplastic Syndromes

Pathogenic Relevance of Germ Line TET2 Alterations

Quantification of Erythroblast- and Myelocyte-Derived mRNAs in Plasma Exosomes As an Indicator of Bone Marrow Status in Patients with Various Types of Anemias and Myeloproliferative Disorders

Incorporation of Molecular Data into the Current Prognostic Models in Treated Patients with Myelodysplastic Syndromes: Which Model Is the Best

Germline Variants of RUNX-1 in Myeloid Malignancy

A Phase 1 Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib (MLN9708) for Relapsed/ Refractory Acute Myeloid Leukemia (AML)

Phenotype/Genotype Associations in TET2-Driven Myeloid Neoplasms

Distinct Clinical and Biological Implications of Various DNTMT3A Mutations in Myeloid Neoplasms

Impact of Erythropoietic Stimulating Agents on Mutational Composition in Patients with Low-Risk Myelodysplastic Syndromes

Molecular and Clinical Characterization of Patients with Myeloid Neoplasms Carrying the 12p Deletion

Next-Generation Sequencing Analysis of Clonal Hierarchy and Dynamics in T-Large Granular Lymphocyte Leukemia Suggests Emergence of STAT3 Clones within Pre-Existing Dominant T-Cell Repertoire Responses Otherwise Silenced in Normal Individuals

PHF6 Somatic Mutations and Their Functional Role in the Pathophysiology of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

the Impact of Clonal Dynamics on Prognosis and Outcome in Myelodysplastic Syndromes

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American Society of Hematology

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American Society of Hematology

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