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Journal Articles

AML Xenografts Undergo Extensive Clonal Competition and Unmask Rare Clones in Patient Samples

Carl Sandén, PhD, Henrik Lilljebjörn, PhD, Christina Orsmark-Pietras, PhD, Karim Saba, MSc, Carl Högberg, PhD, Marianne Rissler, MSc, Vladimir Lazarevic, MD PhD, Gunnar Juliusson, MD PhD, Helena Ågerstam, PhD, Thoas Fioretos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2621.
https://doi.org/10.1182/blood-2018-99-110497
Published: 2018
Journal Articles

Interleukin 4 Induces Macrophage-Mediated Phagocytosis of Leukemia Cells

Pablo Peña-Martínez, Mia Eriksson, PhD, Ramprasad Ramakrishnan, Marion Chapellier, PhD, Carl Högberg, PhD, Caroline Jansson, David Gisselsson Nord, MD PhD, Marcus Järås, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2730.
https://doi.org/10.1182/blood-2018-99-110606
Published: 2018
Journal Articles

CXCR4 Has a CXCL12-Independent Essential Role in MLL-AF9 Driven Acute Myeloid Leukemia

Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, PhD, Carl Högberg, PhD, Marion Chapellier, PhD, Mansi Shah, PhD, Björn Nilsson, MD PhD, Benjamin L. Ebert, MDPhD, Ravi Bhatia, MD, Marcus Järås, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 774.
https://doi.org/10.1182/blood-2018-99-116137
Published: 2018
Journal Articles

IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

Helena Ågerstam, Nils Hansen, Sofia von Palffy, Carl Sandén, Kristian Reckzeh, Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Maria Askmyr, Carl Högberg, Marianne Rissler, Kimmo Porkka, Hans Wadenvik, Satu Mustjoki, Johan Richter, Marcus Järås, Thoas Fioretos
Journal: Blood
Blood (2016) 128 (23): 2683–2693.
https://doi.org/10.1182/blood-2015-11-679985
Published: 2016
Includes: Supplemental data
Journal Articles

Mutational and Clonal Dynamics in Patient-Derived Xenografts of Acute Myeloid Leukemia

Carl Sandén, Karim Saba, Christina Orsmark-Pietras, Henrik Lilljebjörn, Carl Högberg, Marianne Rissler, Vladimir Lazarevic, Gunnar Juliusson, Helena Ågerstam, Thoas Fioretos
Journal: Blood
Blood (2016) 128 (22): 1154.
https://doi.org/10.1182/blood.V128.22.1154.1154
Published: 2016
Journal Articles

IL1RAP Antibodies Block IL1-Induced Expansion of Primitive CML Cells and Display Therapeutic Effects in Xenograft Models

Helena Ågerstam, Nils Hansen, Sofia Von Palffy, Carl Sandén, Kristian Reckzeh, Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Maria Askmyr, Carl Högberg, Marianne Rissler, Kimmo Porkka, Hans Wadenvik, Satu Mustjoki, Johan Richter, MD, Marcus Järås, Thoas Fioretos
Journal: Blood
Blood (2016) 128 (22): 1118.
https://doi.org/10.1182/blood.V128.22.1118.1118
Published: 2016
Journal Articles

Interleukin-4 Is a Negative Regulator of Acute Myeloid Leukemia Cells

Pablo Enrique Peña Martínez, MSc, Marion Chapellier, PhD, Mia Eriksson, Ramprasad Ramakrishnan, MSc, Carl Högberg, PhD, Marcus Järås, PhD
Journal: Blood
Blood (2014) 124 (21): 2146.
https://doi.org/10.1182/blood.V124.21.2146.2146
Published: 2014
Journal Articles

Modeling Chronic Myeloid Leukemia in Immunodeficient Mice Reveals an Inflammatory State with Expansion of Aberrant Mast Cells and Accumulation of Pre B Cells

Maria Askmyr, PhD, Helena Agerstam, PhD, Henrik Lilljebjörn, PhD, Nils Hansen, PhD, Christine Karlsson, PhD, Niklas Landberg, Carl Hogberg, PhD, Carin Lassen, Msc, Marianne Rissler, Johan Richter, MD PhD, Mats Ehinger, MD PhD, Marcus Jaras, PhD, Thoas Fioretos, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3132.
https://doi.org/10.1182/blood.V124.21.3132.3132
Published: 2014
Journal Articles

Toll-like Receptor 1 Is a Candidate Therapeutic Target in Acute Myeloid Leukemia

Mia Eriksson, Pablo Peña, Marion Chapellier, PhD, Carl Högberg, PhD, Thoas Fioretos, MD PhD, Benjamin L Ebert, MD PhD, Marcus Järås, PhD
Journal: Blood
Blood (2014) 124 (21): 5782.
https://doi.org/10.1182/blood.V124.21.5782.5782
Published: 2014
Journal Articles

Upregulation Of IL1RAP On Human Progenitor/Stem Cells Induces Features Of a Myeloproliferative Disorder In Mice

Nils Hansen, Kristian Reckzeh, PhD, Helena Agerstam, PhD, Maria Askmyr, PhD, Sandra Gordon, Marianne Rissler, Carl Högberg, PhD, Johan Richter, MD, PhD, Marcus Järås, PhD, Thoas Fioretos, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1650.
https://doi.org/10.1182/blood.V122.21.1650.1650
Published: 2013